187 results on '"Morton, David P."'
Search Results
2. Green analytical profiling of Teucrium chamaedrysL. using natural deep eutectic solvents and planar chromatography: a greenness assessment by the National Environmental Methods Index and analytical eco-scale
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Lazović, Mila, Cvijetić, Ilija, Trifković, Jelena, Agatonović-Kuštrin, Snežana, Morton, David, and Ristivojević, Petar
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Owing to the use of large volumes of toxic solvents and reagents, green analytical methods have gained increasing importance in natural product research. Herein, a green approach is proposed using the natural deep eutectic solvents (NADES) for the extraction and separation of phenols from Teucrium chamaedrysby use of an ecofriendly high-performance thin-layer chromatography (HPTLC) method. Principal component analysis was used to classify NADES extracts based on HPTLC data. The method’s greenness was assessed using two different tools: the National Environmental Methods Index (NEMI) and the analytical eco-scale. This method can also find application in routine quality control analysis of the investigated medicinal herb with minimal harm to the environment or human health.
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- 2023
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3. Tracked tissue sensing for tumor bed inspection
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Linte, Cristian A., Siewerdsen, Jeffrey H., Morton, David, Connolly, Laura, Groves, Leah, Sunderland, Kyle, Jamzad, Amoon, Rudan, John F., Fichtinger, Gabor, Ungi, Tamas, and Mousavi, Parvin
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- 2023
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4. Real-time integration between Microsoft HoloLens 2 and 3D Slicer with demonstration in pedicle screw placement planning
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Pose-Díez-de-la-Lastra, Alicia, Ungi, Tamas, Morton, David, Fichtinger, Gabor, and Pascau, Javier
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Purpose: Up to date, there has been a lack of software infrastructure to connect 3D Slicer to any augmented reality (AR) device. This work describes a novel connection approach using Microsoft HoloLens 2 and OpenIGTLink, with a demonstration in pedicle screw placement planning. Methods: We developed an AR application in Unity that is wirelessly rendered onto Microsoft HoloLens 2 using Holographic Remoting. Simultaneously, Unity connects to 3D Slicer using the OpenIGTLink communication protocol. Geometrical transform and image messages are transferred between both platforms in real time. Through the AR glasses, a user visualizes a patient’s computed tomography overlaid onto virtual 3D models showing anatomical structures. We technically evaluated the system by measuring message transference latency between the platforms. Its functionality was assessed in pedicle screw placement planning. Six volunteers planned pedicle screws' position and orientation with the AR system and on a 2D desktop planner. We compared the placement accuracy of each screw with both methods. Finally, we administered a questionnaire to all participants to assess their experience with the AR system. Results: The latency in message exchange is sufficiently low to enable real-time communication between the platforms. The AR method was non-inferior to the 2D desktop planner, with a mean error of 2.1 ± 1.4 mm. Moreover, 98% of the screw placements performed with the AR system were successful, according to the Gertzbein–Robbins scale. The average questionnaire outcomes were 4.5/5. Conclusions: Real-time communication between Microsoft HoloLens 2 and 3D Slicer is feasible and supports accurate planning for pedicle screw placement.
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- 2023
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5. Supporting the needs of midwives caring for women with perinatal loss in South Africa
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Kave, Yekiswa V, Sonti, Balandeli SI, Morton, David G, and James, Sindiwe
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Background/AimMidwives play an important role in assisting women to cope with the initial trauma of perinatal loss, but their own coping and support needs can be overlooked. The purpose of the study was to explore the coping behaviours and support needs of midwives caring for women with perinatal loss.MethodsA qualitative, exploratory, descriptive design was used. Data were collected using semi-structured one-on-one interviews with 13 purposively sampled participants from the Nelson Mandela Bay Health District.ResultsThree themes emerged concerning midwives' coping mechanisms in relation to perinatal loss, their views on support from management and the need for psychological and emotional support.ConclusionsThe participants felt the need for unit-based psychological and emotional support. They called for the development of a protocol for midwives to manage perinatal loss events. They felt that the layout of the labour wards needed to be redesigned and that the problem of staff shortages needed to be urgently addressed.
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- 2023
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6. Facilitators and challenges experienced by nursing homes enrolling in the CDC national health care safety network.
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Braun, Barbara I., Longo, Beth Ann, Thomas, Rene, Bell, Jeneita M., Anttila, Angela, Shen, Yanhong, Morton, David, Rowe, Theresa A., and Stone, Nimalie D.
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• Few studies examine nursing home readiness for standardized infection reporting. • This study examined facilitators and challenges that influence NHSN enrollment. • Self-perceived capabilities were associated with shorter time to NHSN enrollment. • Most implementation challenges related to insufficient staff time and resources. • Nursing homes valued externally-facilitated implementation during NHSN enrollment. Standardized measurement of health care-associated infections is essential to improving nursing home (NH) resident safety, however voluntary enrollment of NHs in Centers for Disease Control and Prevention's National Healthcare Safety Network (NHSN) requires several steps. We sought to prospectively identify NH structural, process or staff characteristics that affect enrollment and data submission among a cohort of NHs receiving facilitated implementation. The evaluation employed a mixed methods approach. The meta-theoretical Consolidated Framework for Implementation Research was used to analyze reported facilitators and challenges. Primary and secondary outcomes were time to NHSN enrollment and data submission, respectively. Of 36 participating NHs, 27 (75%) completed NHSN enrollment and 21 (58%) submitted 1 or more months of infection data during the 8-month study period. Mean days to complete enrollment was 82 (standard deviation [SD] = 24, range = 51-139) and days to first data submission was 112 (SD = 45, range = 71-245). Characteristics of NH staff liaisons associated with shorter time to enrollment included infection prevention and control knowledge, personal confidence, and responsibility for infection prevention and control activities. Facility characteristics were not associated with outcomes. Time to NHSN enrollment and submission related more to characteristics of the person leading the process than to characteristics of the NH. External partnerships that provide real-time support and resources are important assets in promoting successful NH participation in NHSN. [ABSTRACT FROM AUTHOR]
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- 2021
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7. The Critical Temperatures of a Number of (i) (Chloroalkane (C3–C4) + Hydrocarbon (C6–C7)) Binary Mixtures and (ii) (Aromatic Halocarbon (Chlorobenzene, Fluorobenzene, 1,2-Dichlorobenzene, or 1,3-Dichlorobenzene) + Alkane (C8)) Binary Mixtures
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Young, Colin L., Tran, Cam A., and Morton, David W.
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In the last 30 years, little experimental work has been reported on the critical properties of (halogenated hydrocarbon + hydrocarbon) mixtures. Furthermore, the overall amount of reported critical property data for these types of mixtures is quite small. This work aims to extended the existing data set and presents data on the critical temperatures of (i) 14 different chloroalkane (C3–C4) + hydrocarbon mixtures (C6–C7) as a function of mole fraction and (ii) 10 different aromatic halocarbons (chlorobenzene, fluorobenzene, 1,2-dichlorbenzene, or 1,3-dichlorobenzene) + alkanes (C8) as a function of mole fraction. All of the (gas + liquid) critical lines were continuous. Therefore, all mixtures displayed either Type I or Type II behavior.
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- 2024
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8. Job satisfaction of registered nurses in a private critical care unit in the Eastern Cape: A pilot study.
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Morton, David, Bowers, Candice, Wessels, Lauren, Koen, Angelique, and Tobias, Juanita
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Background: Job satisfaction is influenced by factors that are interpersonal (between nurse and colleagues), intrapersonal (within the nurse) and extra-personal (external to the nurse). Aim: The primary objective of this study was to explore and describe factors influencing the job satisfaction of registered nurses in a particular private critical care unit. The second objective was to make recommendations to enhance the job satisfaction of registered nurses in this private critical care unit. Setting: The population consisted of registered nurses in a private critical care unit in the Eastern Cape. Methods: This study utilised a quantitative descriptive design. Self-administered questionnaires were distributed amongst registered nurses in the critical care unit. Data were analysed and illustrated through tables. Results: Altogether, 39 registered nurses took part in the study. The majority of the participants (82%; n = 32) indicated that they enjoyed working with their team members. In addition, it was apparent that the majority (79%; n = 30) felt that they were sufficiently trained. Staff members felt that they had management support and felt satisfied at their workplace. Areas of concern included salaries, leave, debriefing and recognition. Conclusion: The majority of the registered nurses in this private critical care unit were extremely satisfied with their job. However, there were areas where this could be improved. The high levels of satisfaction at this single critical care unit lead to the question whether this situation is common throughout the Eastern Cape, which opens the path for further research in this regard. [ABSTRACT FROM AUTHOR]
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- 2020
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9. Advocating for animal rights
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Morton, David
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- 2023
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10. Job satisfaction of nurses working in public hospitals: perceptions of nurse unit managers in South Africa
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Morton, David, Topper, Kegan, Bowers, Candice, Jardien-Baboo, Sihaam, Nyangeni, Thando, and Mabitja, Moeta
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Background:Job satisfaction among nurses often determines whether they choose to remain in the profession or in the facility where they work.Aim:The study sought to explore and describe the job satisfaction of registered nurses in South Africa through the lens of their nurse unit managers.Methods:A qualitative, exploratory, descriptive design was undertaken. Fourteen unit managers were interviewed and Tesch's method of data analysis was used.Findings:Four themes emerged: ‘staff shortages lead to nurses feeling overwhelmed and frustrated’, ‘nurses’ work performance is undermined by limited resources and poor infrastructure', ‘discontent among nurses with regard to poor top level and human resource management’ and ‘despite challenges, nurses experience rare moments of job satisfaction’.Conclusion:Unit managers need to find ways to enhance existing elements of job satisfaction by emphasising the nurse–patient relationship and teamwork among their staff in order to improve the overall job satisfaction of staff.
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- 2020
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11. Models for skin and brain penetration of major components from essential oils used in aromatherapy for dementia patients
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Agatonovic-Kustrin, Snezana, Chan, Chloe Ke Yi, Gegechkori, Vladimir, and Morton, David W.
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AbstractAromatherapy with essential oils (EOs) has been linked to improvement of cognitive function in patients with dementia. In order to act systemically, active EO components must be absorbed through the skin, enter the systemic circulation, and cross the blood brain barrier (BBB). Thus, the aim of this work was to develop quantitative structure activity relationships (QSARs), to predict skin and blood barrier penetrative abilities of 119 terpenoids from EOs used in aromatherapy. The first model was based on experimentally measured skin permeability for 162 molecules, and the second model on BBB permeability for 138 molecules. Each molecule was encoded with 63 calculated molecular descriptors and an artificial neural network was used to correlate molecular descriptors to permeabilities. Developed QSAR models confirm that EOs components penetrate through the skin and across the BBB. Some well-known descriptors, such as log P (lipophilicity), molecular size and shape, dominated the QSAR model for BBB permeability. Compounds with the highest predicted BBB penetration were hydrocarbon terpenes with the smallest molecular size and highest lipophilicity. Thus, molecular size is a limiting factor for penetration. Compounds with the highest skin permeability have slightly higher molecular size, high lipophilicity and low polarity. Our work shows that a major disadvantage of novel multitarget compounds developed for the treatment of Alzheimer’s disease is the size of molecules, which cause problems in their delivery to the brain. Therefore, there is a need for smaller compounds, which possess more desirable physicochemical properties and pharmacokinetics, in addition to targeted biological effects.Communicated by Ramaswamy H. Sarma
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- 2020
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12. Analyzing client behavior in a syringe exchange program
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Yang, Haoxiang, Hu, Yue, and Morton, David
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AbstractMultiple syringe exchange programs serve the Chicago metropolitan area, providing support for drug users to help prevent infectious diseases. Using data from one program over a ten-year period, we study the behavior of its clients, focusing on the temporal process governing their visits to service locations and on their demographics. We construct a phase-type distribution with an affine relationship between model parameters and features of an individual client. The phase-type distribution governs inter-arrival times between reoccurring visits of each client and is informed by characteristics of a client including age, gender, ethnicity, and more. The inter-arrival time model is a sub-model in a simulation that we construct for the larger system, which allows us to provide a personalized prediction regarding the client’s time-to-return to a service location so that better intervention decisions can be made with the help of simulation.
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- 2020
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13. A Year-Round Playground Twenty-Seven Hours from Broadway: Re-Assessing Jacksonville's Legacy as an "Almost Hollywood".
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Morton, David
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A Year-Round Playground Twenty-Seven Hours from Broadway: Re-Assessing Jacksonville's Legacy as an 6'Almost Hollywood" by David Morton Attention Producers who contemplate sending companies South this winter... Wefurnish the need of the visiting producer. Essentially Jacksonville in the 19105 "was this close to becoming the country 's premiere destination for movie production" and could have wrested control of the American motion picture industry away from " that other film town."' Blair Miller's Almost Hollywood, follows up on Bean's perspective by stating if he could "venture a guess, it would be that most people have never thought aboutJacksonville's part in the history of moviemaking, much less that it once was a rival of Hollywood." The MPPC also connected film producers with George Kleine, the country's leading film distributor and largest supplier of Eastman Kodak film stock.29 The incorporation of the MPPC, also known as the "Edison Trust", effectively ended the domination of foreign (primarily French) films on American screens, and also standardized the manner in which films were distributed and exhibited. 54 The article goes on to state that the movie people in Jacksonville have made "hundreds of friends, personally and on the screen" and that the "establishment of the studios here has been a vast benefit to the city in many ways.'~55 This effort to attract additional motion picture productions to Jacksonville culminated in October 1914 when with the slogan "anything which helps Florida helps Jacksonville.". [Extracted from the article]
- Published
- 2020
14. Metal ion and contaminant sorption onto aluminium oxide-based materials: A review and future research.
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Islam, Md. Aminul, Morton, David W., Johnson, Bruce B., Pramanik, Biplob Kumar, Mainali, Bandita, and Angove, Michael J.
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METAL ions ,ALUMINUM oxide ,SORPTION - Abstract
Graphical abstract Number of papers used nanosized aluminium oxides (NAOs) as adsorbents to remove pollutants. Sources: Google Scholar, Web of Science and Scopus; Period: 1997–2018. Highlights • Recent application of nanosized aluminium oxides (NAOs) in treating industrial wastewater. • NAOs can remove metal ions, metalloids/anions, dyes, humic substances and phenolic pollutants efficiently. • NAOs, in particular, alumina and boehmite are mostly used for pollutants removal. • Most previous investigations are laboratory scale, limited guidance for process scale-up. Abstract Nanosized aluminium oxides (NAOs) are an important class of minerals widely found in soil, sediment, aquifer, and aquatic environments. Over the decades, these minerals have been explored as sorbents for the removal of wastewater contaminated with metal ions, anions, organic dyes, humic substances, phenolic compounds, pesticides, and pharmaceuticals from contaminated wastewater. This review summarizes the reported research of NAOs as sorbents and provides details on their sorption capacities including maximum removal capacity under various experimental conditions. Information on the composition, synthesis, characterization and experimental parameters together with sorption mechanisms is provided. A compilation of such information is not currently available and so this review should enable workers in the area to make more informed choices on suitable sorbents for large-scale environmental samples and be able to develop more efficient processes for environmental pollutant clean-up. [ABSTRACT FROM AUTHOR]
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- 2018
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15. Game-Theoretic Allocation of Security Investments at Nuclear Reactors.
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Morton, David
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NUCLEAR reactors ,NUCLEAR energy ,BUDGET ,GAME theory ,PROBABILITY theory - Abstract
This paper presents a game-theoretic model to guide defensive strategies for securing a nuclear facility against an attack by a highly rational and knowledgeable adversary. In our sequential play formulation, the defender chooses and implements security upgrades from a given portfolio subject to a budget constraint and in expectation of a fully informed and rational adversary. Then the adversary observes which upgrades are implemented and chooses an attack that maximizes the expected consequence. Hence, we model the situation as a two-person zero-sum game with fully symmetric information. We represent the facility as a directed graph of nodes and arcs, within which adversary capabilities are reflected via nondetection probabilities and travel times across each arc. By correlating the security force response time and probability it will defeat the adversary with the arc where the adversary is detected, we correlate the force-on-force defeat probability with the time the defender has available to prepare for the engagement. We analyze results of the model when defending against an adversary who is targeting the heat sink or offsite power supply components of a reactor. Finally, we evaluate the impact of changes in cost or effectiveness of different solutions on both the defender's optimal set of solutions and the adversary's chosen path. [ABSTRACT FROM AUTHOR]
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- 2018
16. Promoting good ethical practice
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Morton, David, Allen, Kate, Jinks, Beth, Herrtage, Mike, Clark, Michael, Lea, Richard, Clutton, Eddie, Faller, Kiterie, Greenhalgh, Stephen, Fordyce, Peter, Wolfensohn, Sarah, Stevens, Chris, Gillick, Pamela, Menzies‐Gow, Nicola, Killick, David, Morris, Joanna, Martin, David, De Risio, Luisa, and Murrell, Jo
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- 2023
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17. Midwives' perceptions of their role in mode of birth decisions
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Muthige, Noluthando, James, Sindiwe, and Morton, David
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BackgroundMidwives play an important role as advocates and guides for women in labour regarding their choice of mode of birth. However, there is a paucity of research exploring midwives' perceptions of their role in how women make this choice.AimTo explore and describe how midwives perceive their role in facilitating the choice of mode of birth of women in labour at public sector birthing units.MethodA quantitative, exploratory-descriptive design was used. A questionnaire was used to collect data from 288 midwives in public birthing units in the Eastern Cape, South Africa.FindingsThe majority of the participants agreed that women in labour should be allowed to choose their preferred mode of birth. However, nearly half felt that care providers could overrule that decision depending on the health of the mother and the baby.ConclusionMidwives perceived themselves as the main role players in assisting women in labour to make an informed decision regarding the mode of birth that would best suit their circumstances.
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- 2019
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18. Metal ion and contaminant sorption onto aluminium oxide-based materials: A review and future research
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Islam, Md. Aminul, Morton, David W., Johnson, Bruce B., Pramanik, Biplob Kumar, Mainali, Bandita, and Angove, Michael J.
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Number of papers used nanosized aluminium oxides (NAOs) as adsorbents to remove pollutants. Sources: Google Scholar, Web of Science and Scopus; Period: 1997–2018.
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- 2018
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19. Opportunities and constraints of using the innovative adsorbents for the removal of cobalt(II) from wastewater: A review
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Islam, Md. Aminul, Morton, David W., Johnson, Bruce B., Pramanik, Biplob Kumar, Mainali, Bandita, and Angove, Michael J.
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- 2018
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20. The Critical Temperatures of a Number of (i) (Chloroalkane (C3-C4) + Hydrocarbon (C6-C7)) Binary Mixtures and (ii) (Aromatic Halocarbon (Chlorobenzene, Fluorobenzene, 1,2-Dichlorobenzene, or 1...
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Young, Colin L., Tran, Cam A., and Morton, David W.
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- 2017
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21. Efficient portfolios computed with moment-based bounds.
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Morton, David P., Dokov, Steftcho, and Popova, Ivilina
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Using Bernstein polynomials, we derive moment-based bounding approximations on the expected value of a utility function. We show that optimizing these bounds yields a solution, which is mean–variance (MV) or MV-skewness–kurtosis (MVSK) efficient depending on how many moments are included in the approximation. Practitioners actively managing portfolios may find the approximations useful in their pursuit of designing new trading strategies via asset allocation models based on different utility functions. • Provide two-moment and four-moment Bernstein approximations of expected utility. • Define notion of efficient portfolios using four moments of portfolio return. • Give conditions on utilities so proxy optimization models yield efficient portfolios. [ABSTRACT FROM AUTHOR]
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- 2023
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22. Effect of Long Range Order on the Stress Corrosion Susceptibility of a Nickel-33 at% Chromium Alloy.
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Young, George A., Morton, David S., Lewis, Nathan, Morris, Robert, Pyle, Joseph, Barnard, Leland, and Najafabadi, Reza
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Fracture mechanics based stress corrosion testing in high-temperature, high purity water was conducted on a Ni-33 at% Cr (30.7 wt%) binary alloy heat treated to produce different degrees of strength via long range order. The as-fabricated and 475°C/200 h aged samples did not exhibit stress corrosion cracking (SCC) at the test conditions (338°C, K
I ?=?33 MPavm, and 12 SCC H2 /kg H2 O), but the 475°C/2,000 h aged sample was susceptible. Similar to the effect of "cold work," the increased hardness, higher strength, and decreased ductility associated with the development of the long range ordered Ni2 Cr phase is detrimental to SCC resistance. [ABSTRACT FROM AUTHOR]- Published
- 2016
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23. The Two-Stage Examination: A Method to Assess Individual Competence and Collaborative Problem Solving in Medical Students.
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Lindsley, Janet E., Morton, David A., Pippitt, Karly, Lamb, Sara, and Colbert-Getz, Jorie M.
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- 2016
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24. Evaluators and the enhanced Commonwealth performance framework
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Morton, David and Cook, Brad
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The enhanced Commonwealth performance framework was introduced on 1 July 2015 under the Public Governance, Performance and Accountability Act 2013.It should allow the Australian Parliament and public to understand the proper use of public resources, whether the accountable authorities of Commonwealth entities and companies are achieving their purposes and who is benefitting from Commonwealth activity. Demonstrating the achievement of purposes amounts to demonstrating outcomes and impacts. It requires Commonwealth entities and companies to move past an over-reliance on input- and output-focused performance measures. There is a clear role for evaluators in helping entities make this important adjustment. The opportunities lie in helping a larger cross-section of the Commonwealth public service understand and use the evaluators’ toolbox – for example, program theory and qualitative analysis – to improve the quality of published performance information available to the Commonwealth’s stakeholders. The evaluation community has the opportunity to become a centre of key expertise, and to make a critical contribution to building the capability of ‘performance professionals’ across the public sector.
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- 2018
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25. Challenges facing the veterinary profession in Ireland: 2. On-farm use of veterinary antimicrobials
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Magalhães-Sant’Ana, Manuel, More, Simon, Morton, David, and Hanlon, Alison
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Antimicrobial resistance has emerged in recent years as a significant public health threat, which requires both an ethical and a scientific approach. In a recent Policy Delphi study, on-farm use of antimicrobials was a key concern identified by veterinary professionals in Ireland. In this case study (the second in a series of three resulting from a research workshop exploring the challenges facing the veterinary profession in Ireland; the other two case studies investigate clinical veterinary services and emergency/casualty slaughter certification) we aim to provide a value-based reflection on the constraints and possible opportunities for responsible use of veterinary antimicrobials in Ireland. Using a qualitative focus group approach, this study gathered evidence from relevant stakeholders, namely veterinarians working in public and private organisations, a representative from the veterinary regulatory body, a dairy farmer and a general medical practitioner. Three overarching constraints to prudent on-farm use of veterinary antimicrobials emerged from the thematic analysis: ‘Defective regulations’, ‘Lack of knowledge and values’ regarding farmers and vets and ‘Farm-centred concerns’, including economic and husbandry concerns. Conversely, three main themes which reflect possible opportunities to the barriers were identified: ‘Improved regulations’, ‘Education’ and ‘Herd health management’. Five main recommendations arose from this study based on the perspectives of the study participants including: a) the potential for regulatory change to facilitate an increase in the number of yearly visits of veterinarians to farms and to implement electronic prescribing and shorter validity of prescriptions; b) a ‘One Health’ education plan; c) improved professional guidance on responsible use of veterinary antimicrobials; d) improved on-farm herd health management practices; and e) the promotion of a ‘One Farm-One Vet’ policy. These findings may assist Veterinary Council of Ireland and other competent authorities when revising recommendations concerning the prudent use of veterinary antimicrobials in farmed animals.
- Published
- 2017
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26. Challenges facing the veterinary profession in Ireland: 3. emergency and casualty slaughter certification
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Magalhães-Sant’Ana, Manuel, More, Simon, Morton, David, and Hanlon, Alison
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Veterinarians are faced with significant conflicts of interest when issuing certificates for the transport and slaughter of acutely injured and casualty livestock. In a recent Policy Delphi study, emergency and casualty slaughter certification was a key concern identified by veterinary professionals in Ireland. In this case study (the third in a series of three resulting from a research workshop exploring challenges facing the veterinary profession in Ireland; the other two case studies investigate clinical veterinary services and the on-farm use of veterinary antimicrobials), we aim to provide a value-based reflection on the constraints and opportunities for best practice in emergency and casualty slaughter certification in Ireland. Using a qualitative focus group approach, this study gathered evidence from relevant stakeholders, namely a representative from the regulatory body, local authority veterinarians with research experience in emergency slaughter, an animal welfare research scientist, official veterinarians from the competent authority, a private veterinary practitioner, and a member of a farming organisation. Results revealed a conflict between the responsibility of private veterinary practitioners (PVPs) to safeguard the welfare of acutely injured bovines on-farm and the client’s commercial concerns. As a consequence, some PVPs may feel under pressure to certify, for example, an acutely injured animal for casualty slaughter instead of recommending either on-farm emergency slaughter or disposal by the knackery service. Among Official Veterinarians, there are concerns about the pressure within processing plants to accept acutely injured livestock as casualty animals. Confusion pertaining to legislation and definition of fitness to travel also contribute to these dilemmas. Conflicts of interest arise due to the gap between governance and provision to facilitate on-farm emergency slaughter of livestock. Increased availability and acceptance of on-farm emergency slaughter by Food Business Operators (FBOs) would mitigate the need to certify acutely injured animals fit for transport and slaughter and thereby safeguard animal welfare. In the absence of nationwide availability and acceptance of on-farm emergency slaughter by FBOs, consideration should be given to methods to encourage all those involved in the food chain to prioritise animal welfare when in conflict with the commercial value of the animal. Training and guidelines for PVPs on the regulatory landscape and ethical decision-making should become available. The reintroduction of the fallen animal scheme should be considered to support farm animal welfare.
- Published
- 2017
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27. Challenges facing the veterinary profession in Ireland: 1. clinical veterinary services
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Magalhães-Sant’Ana, Manuel, More, Simon, Morton, David, and Hanlon, Alison
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The provision of veterinary clinical services is known to elicit a range of challenges which require an ethical appraisal. In a recent Policy Delphi study, referrals/second opinions and 24 h emergency care were identified as matters of key concern by veterinary professionals in Ireland. In this case study (the first in a series of three resulting from a research workshop exploring challenges facing the veterinary profession in Ireland; the other two case studies investigate the on-farm use of veterinary antimicrobials and emergency/casualty slaughter certification) we aim to provide a value-based reflection on the constraints and possible opportunities for two prominent veterinary clinical services in Ireland: referrals/second opinions and 24 h emergency care. Using a qualitative focus group approach, this study gathered evidence from relevant stakeholders, namely referral and referring veterinarians, clients, animal charities, and the regulatory body. Six overarching, interrelated constraints emerged from the thematic analysis: the need to improve current guidance, managing clients’ expectations, concerns with veterinarian well-being, financial issues, timeliness of referral, and conflicts between veterinary practices. Possible solutions to improve veterinary referral and out-of-hours clinical services included clarifying the terms used in current norms and regulations (namely ‘referral’, ‘second opinion’, ‘24 h emergency care’ and ‘24 h cover’), improved communication (making the client aware of the different levels of veterinary care that are being offered, and transparent and full disclosure of clinical records), and the promotion of Continuing Veterinary Education in communication, business management and ethical decision-making. These findings may help inform the Veterinary Council of Ireland about future recommendations and regulatory measures.
- Published
- 2017
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28. Probing into the Molecular Requirements for Antioxidant Activity in Plant Phenolic Compounds Utilizing a Combined Strategy of PCA and ANN
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Agatonovic-Kustrin, Snezana, W. Morton, David, and Ristivojevic, Petar
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Aim and Objective: This study investigates molecular structural requirements that are responsible for the antioxidant activity in phenolic compounds. Method: Antioxidant activity of compounds was determined with a 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical assay. Principal component analysis (PCA) was used to classify phenolic antioxidants according to the key molecular features that contribute to their antioxidant activity. Artificial neutral networks (ANNs) was used to develop a predictive QSAR model. Results: Both models agreed that structural characteristics of phenolic compounds responsible for the antioxidant activity include: (1) number and position of alcohol groups on the aromatic ring; (2) molecular size; (3) flexibility/bulkiness; and (4) water solubility. PCA has classified data into phenolic acids and flavonoids, suggesting two distinct mechanisms of action. ANN has confirmed different mechanisms of action for flavonoids and polyphenolic acids, i.e. breaking of free radical chain reactions by donation of a hydrogen atom to neutralise a free radical and the chelating ability of polyphenolic acids. Conclusion: Although two phenolic acids may have the same relative polarity, their different functional groups may drastically change the nature of their interactions with free radicals, and their antioxidant activity.
- Published
- 2017
29. The Two-Stage Examination: A Method to Assess Individual Competence and Collaborative Problem Solving in Medical Students
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Lindsley, Janet E., Morton, David A., Pippitt, Karly, Lamb, Sara, and Colbert-Getz, Jorie M.
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- 2016
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30. Predicting Tablet Strength from the Wet Granulation Conditions via the Unified Compaction Curve.
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Nguyen, Thanh H., Morton, David A.V., and Hapgood, Karen P.
- Subjects
STRENGTH of materials ,COMPACTING ,DRUG dosage ,MICROCRYSTALLINE polymers ,TENSILE strength - Abstract
Tablets make up approximately one third of all drug dosage forms which makes tablet manufacture a common process in the pharmaceutical industry. The unified compaction curve [1] is a model developed initially to look at the impact of the roller compaction conditions on the tablet strength. The tensile strength of the tablets made from formulations containing at least 50% microcrystalline cellulose produced at roller compaction pressures were measured and the profiles were collapsed into a single master “unified compaction curve” (UCC). This allowed for the tablet strength to be predicted from the roller compaction condition and formulations and target the required tablet strength criterion set by standards or specifications [1] . The unified compaction curve was applied to investigate the effects of the wet granulation conditions in a 5L Key granulator on the tablet tensile strength. The study was based on a placebo formulation comprising of 50wt% microcrystalline cellulose, 50wt% lactose and a 5w/v% PVP (K90) binder solution. The effects of the liquid level (20-50wt%), wet massing time (0-10 minutes), binder flow rate (130 g/min and 280 g/min) and impeller speed (150, 285 and 600 rpm) on the tablet strength were explored. Scale-down experiments to a 1L mixer bowl were also conducted. Tablets were produced on a single station carver press with controlled force. A series of compaction profiles were created to represent the relationship between the tablet tensile strength, compaction pressure and the granulation condition. By fitting the unified compaction curve model to the data using a shifting intercept approach, the profiles exploring each granulation condition collapsed onto a single master curve which predicts the tablet strength as a function of the liquid level, wet massing time or the binder flow rate. Increasing the liquid level and/or wet massing time caused a reduction in the tablet hardness when compressed at the same compaction force, and the reduction is postulated to be proportional to the effective compaction forces experienced during granulation, P WGC . The P WGC data further collapses onto a single master curve which is solely a function of the total number of impeller revolutions. Further characterization of the granules produced at these conditions showed that the UCC intercept parameter, P WGC was inversely proportional to the granule porosity, linking the granule microstructure directly and quantitatively to the tablet strength during compaction. This is a significant finding that will allow formulators to optimize tablet hardness via a simple adjustment to the granulation conditions. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
31. APPENDIX D: Protection and Advocacy Organizations.
- Author
-
Morton, David
- Subjects
DISABILITIES ,SOCIAL security - Abstract
Several protection and advocacy organizations that appeared in issue of "Nolo's Guide to Social Security Disability," are presented.
- Published
- 2010
32. APPENDIX C: Medical-Vocational Rules.
- Author
-
Morton, David
- Subjects
INFLUENCE of age on ability ,EDUCATION - Abstract
A variety of medical-vocational rules including age, education and work experience that appeared in the issue of "Nolo's Guide to Social Security Disability," is presented.
- Published
- 2010
33. APPENDIX B: Examples of Technical Rationales for Denials.
- Author
-
Morton, David
- Subjects
DISABILITIES ,INTELLECTUAL disabilities - Abstract
A variety of examples related to technical rationales for denials that appeared in the issue of "Nolo's Guide to Social Security Disability," is presented.
- Published
- 2010
34. APPENDIX A: Glossary of Bureaucratic Terms.
- Author
-
Morton, David
- Subjects
GLOSSES & glossaries ,EXAMINERS (Administrative procedure) - Abstract
A glossary of bureaucratic terms related to the U.S. Social Security Administration (SSA).
- Published
- 2010
35. CHAPTER 15: Your Right to Representation.
- Author
-
Morton, David
- Subjects
DISABILITY insurance ,SOCIAL security - Abstract
Chapter 15 of the book "Nolo's Guide to Social Security Disability," is presented. It mentions about an authorized representative of an individual who receives disability benefits from the U.S. Social Security Administration (SSA). It mentions that in such cases the SSA works with the authorized representative instead of the claimant. It further mentions that an authorized representative could be either an attorney representative or a nonattorney representative.
- Published
- 2010
36. CHAPTER 14: Continuing Disability Review.
- Author
-
Morton, David
- Subjects
DISABILITY insurance ,PHYSICIANS - Abstract
Chapter 14 of the book "Nolo's Guide to Social Security Disability," is presented. It offers information about the continuing disability review (CDR). It mentions that the U.S. Social Security Administration (SSA) reviews all the individuals who receive disability benefits, at regular intervals. CDR is a complex process and is conducted by the officials of the Disability Determination Services (DDS) along with a disability examiner and a doctor.
- Published
- 2010
37. CHAPTER 13: Once You Are Approved.
- Author
-
Morton, David
- Subjects
DISABILITY insurance ,SOCIAL security - Abstract
Chapter 13 of the book "Nolo's Guide to Social Security Disability," is presented. It discusses the situation after an individual has been granted disability benefits from the U.S. Social Security Administration (SSA). It mentions that a Certificate of Award is given to the person who has been granted disability benefits. This certificate contains, answers to the questions concerning SSA. It further mentions on how a payment is decided for a person.
- Published
- 2010
38. CHAPTER 12: Appealing If You Claim Is Denied.
- Author
-
Morton, David
- Subjects
EXAMINERS (Administrative procedure) ,DISABILITY insurance claims - Abstract
Chapter of the book "Nolo's Guide to Social Security Disability," is presented. It offers information about the request for reconsideration of the application by the claimant applying for disability benefits to the U.S. Social Security Administration (SSA). If the SSA has rejected a claim even after reconsideration then the claimant can appeal to an administrative law judge, SSA Appeals Council and federal courts.
- Published
- 2010
39. CHAPTER 11: Reasons You May Be Denied Benefits.
- Author
-
Morton, David
- Subjects
DISABILITY insurance ,MEDICAL records - Abstract
Chapter 11 of the book "Nolo's Guide to Social Security Disability," is presented. It discusses the reasons for which an individual may be denied disability benefits offered by the U.S. Social Security Administration (SSA). The various factors contributing to the denial of services include, an individual having enough income and possessions, lack of communication between the claimant and SSA and absence of proper medical records from the claimant.
- Published
- 2010
40. CHAPTER 10: When Benefits Begin.
- Author
-
Morton, David
- Subjects
DISABILITY insurance ,SOCIAL security - Abstract
Chapter 10 of the book "Nolo's Guide to Social Security Disability," is presented. It offers information on the onset date used by the U.S. Social Security Administration (SSA) which represents the date on which the person became disabled. The several onset dates used by the SSA include Alleged onset date, Medical onset date and Established onset date. It mentions that the onset dates are important because the SSA may pay disability benefits prior to application.
- Published
- 2010
41. CHAPTER 9: How Age, Education, and Work Experience Matter.
- Author
-
Morton, David
- Subjects
INFLUENCE of age on ability ,DISABILITY insurance - Abstract
Chapter 9 of the book "Nolo's Guide to Social Security Disability," is presented. It focuses on the medical-vocational factors considered by the U.S. Social Security Administration (SSA), while deciding the level of disability of an individual. The various vocational factors include, age, education and work experience. It further mentions that age, ability and work experience are important vocational factors as these determines an individual's capability and ability to adopt to work situation.
- Published
- 2010
42. CHAPTER 8: If You Can Do Some Work.
- Author
-
Morton, David
- Subjects
DISABILITY insurance ,DISABILITIES - Abstract
Chapter 8 of the book "Nolo's Guide to Social Security Disability," is presented. It offers information about the Residual Functional Capacity (RFC) of the U.S. Social Security Administration (SSA). It mentions that RFC is an assessment from the SSA under which an individual is considered to be capable of doing some work despite of his physical disabilities, impairments and related symptoms. The RFC assessment is a medical decision that determines an individual's degree or level of disability.
- Published
- 2010
43. CHAPTER 7: How Claims Are Decided.
- Author
-
Morton, David
- Subjects
DISABILITY insurance ,EXAMINERS (Administrative procedure) - Abstract
Chapter 7 of the book "Nolo's Guide to Social Security Disability," is presented. It discusses the process of scrutinizing the applications for disability benefits. It mentions that whether an application is processed at the Disability Determination Service (DDS), in the federal court and an administrative law judge (ALJ), the U.S. Social Security Administration (SSA) require that issues must be evaluated in a particular order. It further discusses the various steps which are followed.
- Published
- 2010
44. CHAPTER 6: Who Decides Your Claim?
- Author
-
Morton, David
- Subjects
FEDERAL regulation ,DISABILITY insurance - Abstract
Chapter 6 of the book "Nolo's Guide to Social Security Disability," is presented. It offers information on the Disability Determination Services (DDS) of the U.S. Social Security Administration (SSA). It mentions that the DDS makes a final decision on the applications claiming for disability benefits. The DDS offices receive, funds from the federal government and follows federal laws and regulations.
- Published
- 2010
45. CHAPTER 5: Proving You Are Disabled.
- Author
-
Morton, David
- Subjects
MEDICAL records ,DISABILITY insurance - Abstract
Chapter 5 of the book "Nolo's Guide to Social Security Disability," is presented. It discusses the documents required while applying for the disability benefits offered by the U.S. Social Security Administration (SSA). It mentions that any individual applying for the disability benefits must provide the SSA authentic, thorough and sufficient medical records. It further mentions that after receiving the documents the SSA reviews the genuineness of the records and the source hospital or clinic.
- Published
- 2010
46. CHAPTER 4: Getting Benefits During the Application Process.
- Author
-
Morton, David
- Subjects
SUPPLEMENTAL security income program ,DISABILITY insurance ,SOCIAL security - Abstract
Chapter 4 of the book "Nolo's Guide to Social Security Disability," is presented. It offers information on the presumptive disability (PD) payments offered by the U.S. Social Security Administration (SSA). It mentions that PD are offered to those individuals who while applying for Supplemental Security Income (SSI) program are found eligible for the disabled payments. An individual may receive PD from SSA up to 6 months while the application for disability benefits is still under process.
- Published
- 2010
47. CHAPTER 3: Disability Benefits for Children.
- Author
-
Morton, David
- Subjects
SERVICES for children with disabilities ,SUPPLEMENTAL security income program - Abstract
Chapter 3 of the book "Nolo's Guide to Social Security Disability," is presented. It focuses on the disability benefits offered to children by the U.S. Social Security Administration (SSA). It mentions that children under the age of 18 years are considered for Social Security Disability Insurance (SSDI) and Supplemental Security Income (SSI), if the child depends on a person receiving disability benefits or death of the person receiving disability benefits on whom, the child was dependent.
- Published
- 2010
48. CHAPTER 2: Applying for Disability Benefits.
- Author
-
Morton, David
- Subjects
PEOPLE with disabilities ,DISABILITY insurance ,INTERNET - Abstract
Chapter 2 of the book "Nolo's Guide to Social Security Disability," is presented. It offers suggestions to apply for a disability claim at the U.S. Social Security Administration (SSA). The basic information required by the SSA include proper documentation of the symptoms, medical record from the doctor and record related to the impact of illness on the job. It also offers information on applying disability benefits at the local office, over phone and Internet and lists the documents required.
- Published
- 2010
49. CHAPTER 1: What Is Social Security Disability?
- Author
-
Morton, David
- Subjects
SUPPLEMENTAL security income program ,DISABILITY insurance - Abstract
Chapter 1 of the book "Nolo's Guide to Social Security Disability," is presented. It focuses on the programs under which the U.S. Social Security Administration (SSA) grant disability payments. These program are Social Security Disability Insurance (SSDI), for workers who have contributed to Social Security trust fund and Supplemental Security Income (SSI), for disabled individuals with limited income. It also discusses the various eligibility criteria to qualify for SSDA and SSI.
- Published
- 2010
50. Your Social Security Disability Companion.
- Author
-
Morton, David
- Subjects
SUPPLEMENTAL security income program ,PUBLIC health ,DISABILITIES ,INTELLECTUAL disabilities - Abstract
The article focuses on the Social Security disability benefits provided by the U.S. government. It mentions that the social security disability benefits are supervised by the U.S. Social Security Administration (SSA) of the U.S. The benefits offered by the SSA include financial support to the individuals with mental or physical disorders. It further mentions that the SSA grant disability payments under Social Security Disability Insurance (SSDI) and Supplemental Security Income (SSI).
- Published
- 2010
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