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Daily sedative interruption (DSI) may reduce excessive sedation and shorten the duration of mechanical ventilation. It is not clear, however, how DSI affects sleep characteristics. For patients receiving mechanical ventilation, we compared the effect on sleep quality of DSI and continuous sedation (CS).Twenty-two mechanically ventilated patients who were receiving midazolam by infusion were randomly assigned to two groups, DSI (n=11) or CS (n=11). In the DSI group, sedatives were interrupted until the patients awoke and expressed discomfort, after which midazolam or opioids were administered intermittently as needed during the daytime (0600 to 2100 hours); during the night (2100 to 0600) midazolam was administered intravenously to maintain Ramsay sedation scale 4 to 5. In the CS group, the sedatives were titrated to obtain Ramsay sedation scale 4 to 5 throughout the day. The polysomnography of each patient was recorded continuously over a 24 hour period. Sleep stages were analysed using Rechtschaffen and Kales criteria.In the DSI group, the amount of stage 3 and 4 non-rapid eye movement sleep (slow wave sleep) was longer (6 vs 0 minutes, P=0.04) and rapid eye movement sleep was longer than in CS (54 vs 0 minutes, P=0.02). In the CS group, total sleep time during night-time was longer (8.7 vs 7.3 hours, P=0.047) and frequency of arousal was lower (2.2 vs 4.4 event/hour, P=0.03) than those in the DSI group. All mechanically ventilated patients demonstrated abnormal sleep architecture, but, compared with CS, DSI increased the amount of slow wave sleep and rapid eye movement sleep.

AbstractAn evaluation is essential in an attempt to assess the relative effectiveness of one approach against the other. Many communication channels have been used in agricultural extension services and it is through evaluation that appropriateness and effectiveness of such channels can be determined. To facilitate the task of evaluation among researchers, it is necessary to put in place a model such as the one being proposed by this paper. In the model, a professionally designed and packaged extension messages in form of improved agricultural technologies emanate from an extension agency which constitutes the communication source. The next stage in the model is the use of communication channels. This entails decision by the target audience to use a particular channel, amount of content, and in a particular manner, which can be determined by many socio-economic variables. Effect of an extension programme on the target audience through a particular channel can be operationalized through observable changes in their attitude, knowledge and practice of the innovations leading to enhanced technical competence and increased farm output.

AbstractOne of the most pressing issues in minds of people in Nigeria as far as education is concerned today is that pertaining to the quality or standard of education. Qualitative education should lead to detectable gains in knowledge, skills and values. There are, however, several students’ vices that seem to be militating against realization of the desired qualitative education in Nigerian tertiary institutions. Some of these vices are cultism, drug abuse, examination malpractice, obscene dressing and sexual promiscuity/harassment. Each of these vices and the possible social and academic implications are explained. Major employers of Nigerian graduates have widely agreed on quality decline in higher education in the country, particularly in the areas of communication in oral and written English and technical proficiency. It is recommended that the responsibility of preventing or curbing general students’ vices in Nigerian tertiary institutions be a collective one resting on parents, teachers, religious leaders, authorities of the institutions as well as government. This can be done through appropriate upbringing, counseling and necessary sanctions.