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1. Armillaria mellea component armillarikin induces apoptosis in human leukemia cells.

Author

Chen, Yu-Jen, Wu, Szu-Yuan, Chen, Chien-Chih, Tsao, Yu-Lin, Hsu, Nai-Chi, Chou, Yu-Chi, and Huang, Huey-Lan

Abstract

Highlights: [•] Armillarikin is a compound isolated from medicinal mushroom Armillaria mellea. [•] Armillarikin induces apoptosis in human K562, U937 and HL-60 leukemia cells. [•] Armillarikin increases production of intracellular ROS in human leukemia cells. [•] ROS scavengers attenuate armillarikin-induced apoptosis. [•] Armillarikin-induced apoptosis is mediated by ROS production. [Copyright &y& Elsevier]

Published
2014
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