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ABSTRACTThe use of exclusionary discipline (ExD) was compared for U.S. public pre-kindergarten (Pre-K) and K-12 grades within the same school. ExD rates were 10 times higher in K-12 than in Pre-K when calculated for all schools but ExD rates were comparable for schools that reported at least one case of ExD in Pre-K. Additionally, disparities in the use of ExD were observed for both Pre-K and K-12 schools: higher rates were found for boys relative to girls, for Black children relative to White children, and for charter schools relative to non-charter schools. While most schools did not use ExD, when they did, they did so at high rates. The use of ExD appears to be associated with school-level factors including a culture of use.

Residential income segregation is a spatial manifestation of social inequality and is an important factor that influences access to resources, services, and amenities. In general, past research analyzing income segregation has applied index-based methods to describe the separation of low-income households at one spatial scale; however, existing studies have not yet considered how income segregation varies across multiple income classes, spatial scales, and local contexts. This study applies a multilevel multigroup modeling approach to explore the global and local patterns of income segregation between dissemination areas (micro-scale), census tracts (meso-scale), and neighborhoods (macro-scale) in Toronto, Canada. A global model that estimates the overall multiscale segregation of five income classes finds that the most affluent families had the highest levels of segregation and that the segregation of all income classes was strongest at the macro- and micro-scales. A local model that allows the micro-scale segregation measures to vary geographically shows that higher-income families were less segregated in the city center than in the inner suburbs, that middle-income families were highly segregated in areas serviced by public transit, and that almost all income classes had high levels of segregation in disadvantaged neighborhoods prioritized for investment by local policymakers. The methodological and substantive contributions of this study for understanding the complex patterns of income segregation are discussed.

Neighborhood land use composition influences the geographical patterns of property crime. Few studies, however, have investigated if, and how, the relationships between land use and crime change over time. This research applies a Bayesian spatio-temporal regression model to analyze 12 seasons of property crime at the small-area scale. Time-varying regression coefficients estimate the seasonally varying relationships between land use and crime and distinguish both time-constant and season-specific effects. Seasonal property crime trends are commonly hypothesized to be associated with fluctuating routine activity patterns around specific land uses, but past studies do not quantify the time-varying effects of neighborhood characteristics on small-area crime risk. Results show that, accounting for sociodemographic contexts, parks are more positively associated with property crime during spring and summer seasons, and eating and drinking establishments are more positively associated during autumn and winter seasons. Land use is found to have a more substantial impact on spatial, rather than spatio-temporal, crime patterns. Proposed explanations for results focus on seasonal activity patterns and corresponding spatio-temporal interactions with the built environment. The theoretical and analytical implications of this modeling approach are discussed. This research advances past cross-sectional spatial analyses of crime by identifying built environment characteristics that simultaneously shape both where and when crime occurs.

Human papilloma virus (HPV) infection causes cancers and their precursors (high-grade squamous intraepithelial lesions) near cervical and anal squamocolumnar junctions. Recently described cervical squamocolumnar junction cells are putative residual embryonic cells near the cervical transformation zone. These cells appear multipotential and share an identical immunophenotype (strongly CK7-positive) with over 90% of high-grade squamous intraepithelial lesions and cervical carcinomas. However, because the number of new cervical cancers discovered yearly world wide is 17-fold that of anal cancer, we posed the hypothesis that this difference in cancer risk reflects differences in the transition zones at the two sites. The microanatomy of the normal anal transformation zone (n=37) and topography and immunophenotype of anal squamous neoplasms (n=97) were studied. A discrete anal transition zone was composed of multilayered CK7-positive/p63-negative superficial columnar cells and an uninterrupted layer of CK7-negative/p63-positive basal cells. The CK7-negative/p63-positive basal cells were continuous with—and identical in appearance to—the basal cells of the mature squamous epithelium. This was in contrast to the cervical squamocolumnar junction, which harbored a single-layered CK7-positive/p63-negative squamocolumnar junction cell population. Of the 97 anal intraepithelial neoplasia/squamous cell carcinomas evaluated, only 27% (26/97) appeared to originate near the anal transition zone and only 23% (22/97) were CK7-positive. This study thus reveals two fundamental differences between the anus and the cervix: (1) the anal transition zone does not harbor a single monolayer of residual undifferentiated embryonic cells and (2) the dominant tumor immunophenotype is in keeping with an origin in metaplastic (CK7-negative) squamous rather than squamocolumnar junction (CK7-positive) epithelium. The implication is that, at birth, the embryonic cells in the anal transition zone have already begun to differentiate, presenting a metaplasia that—similar to vaginal and vulvar epithelium—is less prone to HPV-directed carcinogenesis. This in turn underscores the link between cancer risk and a very small and discrete population of vulnerable squamocolumnar junction cells in the cervix.

Human papilloma virus (HPV) infection causes cancers and their precursors (high-grade squamous intraepithelial lesions) near cervical and anal squamocolumnar junctions. Recently described cervical squamocolumnar junction cells are putative residual embryonic cells near the cervical transformation zone. These cells appear multipotential and share an identical immunophenotype (strongly CK7-positive) with over 90% of high-grade squamous intraepithelial lesions and cervical carcinomas. However, because the number of new cervical cancers discovered yearly world wide is 17-fold that of anal cancer, we posed the hypothesis that this difference in cancer risk reflects differences in the transition zones at the two sites. The microanatomy of the normal anal transformation zone (n=37) and topography and immunophenotype of anal squamous neoplasms (n=97) were studied. A discrete anal transition zone was composed of multilayered CK7-positive/p63-negative superficial columnar cells and an uninterrupted layer of CK7-negative/p63-positive basal cells. The CK7-negative/p63-positive basal cells were continuous with—and identical in appearance to—the basal cells of the mature squamous epithelium. This was in contrast to the cervical squamocolumnar junction, which harbored a single-layered CK7-positive/p63-negative squamocolumnar junction cell population. Of the 97 anal intraepithelial neoplasia/squamous cell carcinomas evaluated, only 27% (26/97) appeared to originate near the anal transition zone and only 23% (22/97) were CK7-positive. This study thus reveals two fundamental differences between the anus and the cervix: (1) the anal transition zone does not harbor a single monolayer of residual undifferentiated embryonic cells and (2) the dominant tumor immunophenotype is in keeping with an origin in metaplastic (CK7-negative) squamous rather than squamocolumnar junction (CK7-positive) epithelium. The implication is that, at birth, the embryonic cells in the anal transition zone have already begun to differentiate, presenting a metaplasia that—similar to vaginal and vulvar epithelium—is less prone to HPV-directed carcinogenesis. This in turn underscores the link between cancer risk and a very small and discrete population of vulnerable squamocolumnar junction cells in the cervix.

The article features two Catholic university graduates, Dr. Sarah Hicks and David Wallisch. Dr. Hicks was a baptized Lutheran while she was attending Catholic schools in Marshall and Missouri and according to her, the experience she gathered during her time at Rockhurst University enabled her to fell safe as the values were similar to what she used to know. Wallisch is another Rockhurst alumnus who continuously work with the university in its charity works.

Presents the short story "The Tag," by Matthew M. Quick.

Presents a short story "Friends Don't Let Friends Procreate (or WWJD?)," by Matthew M. Quick.

The article presents the short story "The Whiskey Robe," by Matthew M. Quick.

The article shares the author's decision to quit smoking. The author notes that his wife taught him the three-part yogic breath to appreciate the miracle that he has visions. He shares his wish that his grandfather was able to share what he learned through the years of smoke. He also relates how he thinks first about his grandfather whenever he smells cigarette smoke, then about how many inhalations he has left.

Presents the poem "Guidebook, In Which We Live (Where?)," by Matthew M. Quick. First Line: Mr. Chester—who is our surviving elder—is our West. Last Line: of old.