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1. Fatty acid transporter MFSD2A is a multifunctional gatekeeper in brain and placenta

Author

Walter, Justin D., Remm, Sille, and Seeger, Markus A.

Abstract

MFSD2A mediates uptake of the essential fatty acid DHA across the blood–brain barrier. Separately, via interactions with syncytin-2, MFSD2A contributes to the formation of the mother–fetus placental boundary. Cryo-EM analysis of a human MFSD2A–syncytin-2 complex provides new insights into how MFSD2A performs these dual roles.

Published
2022
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