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Un récent évènement indésirable grave (arrêt cardiorespiratoire) chez une patiente ayant eu une anesthésie locale par bloc paracervical lors d’une ponction ovocytaire (PO), nous a fait modifier nos pratiques pour n’utiliser plus que des gels de lidocaïne pour les anesthésies locales avant recueil ovocytaire.

Les fausses couches répétées précoces sont un motif fréquent de consultation. Un bilan étiologique est classiquement proposé aux couples et une prise en charge préventive doit être discutée. Nous avons voulu étudier les issues de grossesses suite à 3 fausses couches consécutives ainsi que les prises en charge proposées dans notre service de gynécologie-obstétrique en hôpital universitaire.

One of the main problems concerning IVF units is the need to decrease the occurrence of multiple pregnancies in their practice without affecting the overall success rate. Different embryological parameters concerning every step of the early embryo development are known to have some predictive value for implantation potential. In this prospective study, a pronuclear scoring system was used to classify zygotes into six patterns from 0 to 5. Cleaved, day 3 embryos developed from pattern 0 zygotes, which was described as the normal pattern, were transferred when available. For each zygote pattern, the subsequent embryological development was analysed. Pattern 0 zygotes led to significantly more 'good quality' embryos with higher implantation potential than embryos developing from the other zygote patterns (P < 0.01). Embryo transfers including at least one pattern 0 resulted in significantly more pregnancies than transfers without any pattern 0 zygotes (39.3 versus 19.7%, P < 0. 01). No relationship between clinical parameters (age of female partner, infertility cause) and zygote pattern distribution was demonstrated.

One of the main problems concerning IVF units is the need to decrease the occurrence of multiple pregnancies in their practice without affecting the overall success rate. Different embryological parameters concerning every step of the early embryo development are known to have some predictive value for implantation potential. In this prospective study, a pronuclear scoring system was used to classify zygotes into six patterns from 0 to 5. Cleaved, day 3 embryos developed from pattern 0 zygotes, which was described as the normal pattern, were transferred when available. For each zygote pattern, the subsequent embryological development was analysed. Pattern 0 zygotes led to significantly more `good quality' embryos with higher implantation potential than embryos developing from the other zygote patterns (P < 0.01). Embryo transfers including at least one pattern 0 resulted in significantly more pregnancies than transfers without any pattern 0 zygotes (39.3 versus 19.7%, P < 0.01). No relationship between clinical parameters (age of female partner, infertility cause) and zygote pattern distribution was demonstrated.