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OBJECTIVE To examine whether patients with no insurance or Medicaid are more likely to present with advanced-stage laryngeal cancer. DESIGN Retrospective cohort study from the National Cancer Database, 1996-2003. SETTING Hospital-based practice. PARTICIPANTS Patients with known insurance status diagnosed as having invasive laryngeal cancer at Commission on Cancer facilities (N = 61 131) were included. Adjusted and unadjusted logistic regression models analyzed the likelihood of presenting at a more advanced stage. MAIN OUTCOME MEASURES Overall stage of laryngeal cancer (early vs advanced) and tumor size (T stage) at diagnosis. RESULTS Patients with advanced-stage laryngeal cancer at diagnosis were more likely to be uninsured (odds ratio [OR], 1.97; 95% confidence interval [CI], 1.79-2.15) or covered by Medicaid (OR, 2.40; 95% CI, 2.21-2.61) compared with those with private insurance. Similarly, patients were most likely to present with the largest tumors (T4 disease) if they were uninsured (OR, 2.92; 95% CI, 2.60-3.28) or covered by Medicaid (OR, 3.97; 95% CI, 3.56-4.34). Patients who were black, between ages 18 and 56 years, and who resided in zip codes with low proportions of high school graduates or low median household incomes were also more likely to be diagnosed as having advanced disease and/or larger tumors. CONCLUSIONS Individuals lacking insurance or having Medicaid are at greatest risk for presenting with advanced laryngeal cancer. Results for the Medicaid group may be influenced by the postdiagnosis enrollment of uninsured patients. It is important to consider the impact of insurance coverage on stage at diagnosis and associated morbidity, mortality, quality of life, and costs.Arch Otolaryngol Head Neck Surg. 2007;133(8):784-790--

Persons living in the United States who lack private medical insurance are less likely to have access to medical care and to take part in cancer screening programs. Regional studies suggest that uninsured and Medicaid-insured individuals are likelier than those who are privately insured to present with advanced-stage cancer, but this has not been confirmed using contemporary national-level information. Complicating the problem is the observation that cancer patients from ethnic minorities are likelier than non-Hispanic whites to be uninsured or Medicaid insured. This study sought relationships between insurance status and disease stage at the time of diagnosis for twelve cancer sites (breast, colorectal, kidney, lung, melanoma, non-Hodgkin lymphoma, ovary, pancreas, prostate, urinary bladder, uterus, thyroid). The study population included 3,742,407 patients whose characteristics resembled those of the U.S. population not included in the analysis. The patients, diagnosed in the years 1998–2004, were enrolled in the U.S. National Cancer Database, a hospital-based registry with patient information from approximately 1430 facilities.