231 results on '"Shen, Fei"'
Search Results
2. Realizing Ultrathin LiSn Alloy Anode by Tuning the Wettability of Molten Li for High-Energy-Density Batteries.
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Chen, Yifei, Zhang, Qihang, Wang, Kaiming, Shen, Mengyuan, Zhang, Liang, Li, Yunpeng, Yuan, Jiamin, Wang, AnLi, Shen, Fei, and Han, Xiaogang
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- 2024
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3. ECOG-ACRIN EAZ171: Prospective validation trial of germline variants and taxane type in association with taxane-induced peripheral neuropathy (TIPN) in Black women with early-stage breast cancer.
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Ballinger, Tarah Jean, Zhao, Fengmin, Sparano, Joseph A., Garcia, Sofia F., Shen, Fei, Virani, Shamsuddin, Srinivasiah, Jayanthi, Stringer-Reasor, Erica Michelle, Chitalia, Ami, Davis, Andrew A., Makower, Della F., Incorvati, Jason, Simon, Melissa A., Mitchell, Edith P., DeMichele, Angela, Miller, Kathy, Wagner, Lynne I., Wolff, Antonio C., and Schneider, Bryan P.
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- 2024
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4. Realizing Ultrathin LiSn Alloy Anode by Tuning the Wettability of Molten Li for High-Energy-Density Batteries
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Chen, Yifei, Zhang, Qihang, Wang, Kaiming, Shen, Mengyuan, Zhang, Liang, Li, Yunpeng, Yuan, Jiamin, Wang, AnLi, Shen, Fei, and Han, Xiaogang
- Abstract
Despite being heralded as the “holy grail” of anodes for their high theoretical specific capacity, lithium (Li) metal anodes still face practical challenges due to difficulties in fabricating ultrathin Li with controllable thickness and suppressing Li dendrites growth. Herein, we introduce a simple and cost-effective dip-coating method to fabricate ultrathin lithium–tin (LiSn) anode with adjustable thicknesses ranging from 4.5 to 45 μm. The in situ formation of Li22Sn5alloy improves the wettability of the molten Li, enabling the casting of ultrathin Li metal layers on different substrates. More importantly, the abundant Li22Sn5lithiophilic sites significantly lower the nucleation overpotential, inducing uniform Li deposition and accelerating the electrochemical reaction at the interface. As a result, the symmetric cell assembled with LiSn–Cu electrodes can cycle stably for more than 120 h with a charge/discharge depth of 50%, which is 1.5 times longer than the lifespan of the pure Li anode. In the full cells paired with NCM cathode, the discharge specific capacity is improved from 13.84 to 70.31 mA h g–1with the LiSn–Cu anode at 8 C. The LiSn–Cu||NCM full cell realized a high energy density of 724.9 Wh kg–1at the active material level with an N/Pratio of 1.4.
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- 2024
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5. Preclinical characterization of human Kallikrein 2 (hK2) as a novel target for the treatment of prostate cancer.
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Shen, Fei, Kelly, William Kevin, Pandit-Taskar, Neeta, McDevitt, Theresa, Smith, Ryan, Menard, Krista, Packman, Kathryn, Chaudhary, Ruchi, Rupnow, Brent, Yu, Margaret K., Guckert, Mary E., Tian, Shaozhou Ken, Chu, Gerald, Xie, Hong, Patricia, Daniel, Max, Steven I, and Morris, Michael J.
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- 2024
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6. Measurement and Analysis of Impulse Source Produced by Ballistic Shock Wave Therapy Device in Different Medium Using PVDF Sensor
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Fan, Fan, Xu, Liansheng, Wu, Qiong, Shen, Fei, Wang, Li, Li, Fengji, Fan, Yubo, and Niu, Haijun
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Purpose: Radial extracorporeal shock wave therapy (rESWT) has been used in clinical and rehabilitation fields. However, the formulation of related clinical treatment protocols and the full potential of its therapeutic efficacy are constrained due to limited understanding of shock wave sources. This study aimed to further clarify the characteristics of shock wave sources generated at different medium interfaces. Methods: Shock wave generated by rESWT device at the interface of different media (soft tissue-mimicking-phantom, water and air) was measured based on flexible polyvinylidene fluoride (PVDF) sensors. The temporal and spectral characteristics of the shock wave source were analyzed. Results: The wave generated at the phantom interface was similar to that at the water interface under the same impact pressure, both being largely different from that at the air interface, where the absolute value of the peak pressure was significantly reduced. The spectral properties of the shock wave generated in different media were similar, with distinct peak frequencies, varying modulation frequencies in phantom (12.2 kHz), water (8.5 kHz), and air (7.2 kHz), and a relatively constant carrier frequency (between 82 and 83 kHz). Under the different impact pressures, there were no variations in the peak frequency at the same medium interface, indicating that the impact pressure mainly impacts the shock wave amplitude, but not the peak frequency. Conclusion: The shock waves generated at different medium interfaces exhibited temporal and spectral differences. Therefore, measurement results in biological soft tissues cannot be simply replaced by the measurement results in air or water. The results of this study are expected to provide important information for evaluating rESWT devices and optimizing clinical shock wave treatment protocols.
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- 2024
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7. An Overview of Contour Detection Approaches
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Gong, Xin-Yi, Su, Hu, Xu, De, Zhang, Zheng-Tao, Shen, Fei, and Yang, Hua-Bin
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Object contour plays an important role in fields such as semantic segmentation and image classification. However, the extraction of contour is a difficult task, especially when the contour is incomplete or unclosed. In this paper, the existing contour detection approaches are reviewed and roughly divided into three categories: pixel-based, edge-based, and region-based. In addition, since the traditional contour detection approaches have achieved a high degree of sophistication, the deep convolutional neural networks (DCNNs) have good performance in image recognition, therefore, the DCNNs based contour detection approaches are also covered in this paper. Moreover, the future development of contour detection is analyzed and predicted.
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- 2024
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8. Information-Aware Driven Dynamic LEO-RAN Slicing Algorithm Joint With Communication, Computing, and Caching
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Chen, Geng, Qi, Shuhu, Shen, Fei, Zeng, Qingtian, and Zhang, Yu-Dong
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With the rapid development of applications with different use cases and service demands for edge network, network slicing is an emerging solution for satisfying service-oriented requirements, while the low earth orbit (LEO) satellite caching-assisted communication has been considered as one of the key elements for effective services. With limited resources at the edge of the radio access network (RAN), it is challenging to take advantage of the LEO content cache to joint allocation of communication, computing and caching space (3C) resources. To this end, we investigate the problem of resource slicing and scheduling of joint 3C resources in RAN edge scenario assisted by LEO content caching. A hierarchical resource slicing framework is proposed for dynamic allocation of multidimensional resources. The optimization variables are relaxed and the constraints are adjusted. The sequential quadratic programming (SQP) iteration algorithm is proposed as theoretical offline baseline. Due to its complex solving process and limited real-time performance, we incorporate Long Short-Term Memory (LSTM) into the Soft Actor-Critic (SAC) algorithm to aware extract the distribution characteristics of historical information and propose the deep reinforcement learning algorithm of LSTM-SAC. Meanwhile, the proportional priority based scheduling algorithm is employed in the intra-slice. Compared to SAC, TD3 and DDPG algorithms, the proposed algorithm is the closest to the theoretical value, improves the objective function by 6.95%, 9.52% and 11.52% respectively, which can significantly improve the system rate while satisfying the service level agreements.
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- 2024
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9. BDS-3/BDS-2 Combined Precise Clock Estimation and Time Transfer Using Ultrarapid Products
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Ge, Yulong, Cao, Xinyun, Jiang, Chenhui, and Shen, Fei
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To provide high-precision timing services of the BeiDou Navigation Satellite System (BDS), this work performs a detailed investigation of integrated BDS-3 and BDS-2 real-time precise point positioning (PPP) time transfer with the ultrarapid products. Compared with the final precise clock products, the average standard deviation (STD) of estimated BDS-3 MEO/IGSO satellites is 0.1 ns, while the corresponding value of BDS-2 is 0.2 ns. The precision of real-time BDS-3/2 PPP time transfer can achieve better than 0.5 ns. The phenomenon of reconvergence and abnormal jumps in receiver clock series can be effectively reduced because of the evenly distributed MEO satellites.
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- 2024
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10. Synthetic Multimode Orbital Angular Momentum Generation and Its Object Detection Application
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Yang, Yang, Chen, Zijun, Wang, Yu, Fu, Jiangnan, Gao, Yuan, Wang, Shaomeng, Shen, Fei, Jiang, Haibo, and Gong, Yubin
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This study proposes a novel method for generating virtual orbital angular momentum (OAM) using a synthetic uniform circular array (SUCA). In the proposed method, the base array is rotated to various spatial locations, with the feeding phases modified accordingly, and the generated fields at various spatial locations are superimposed. The proposed method exchanges the cost of the time domain for more spatial degrees of freedom, which can overcome the limit of space and configure more virtual array elements to generate vortex electromagnetic (EM) waves carrying virtual multimode OAMs. To validate the effectiveness of the proposed method, a radially placed SUCA is designed with four actual elements of a circularly polarized (CP) horn antenna and sixteen virtual elements. The SUCA is then simulated and measured, and it successfully generates fifteen virtual OAMs in the frequency range of 5–6.5 GHz. Furthermore, 2-D object detection experiments of three metal targets with different scales at different positions based on the SUCA were conducted. The experimental results show that the three targets can be distinguished clearly, indicating that our work has the potential to generate more virtual OAMs and improve object detection resolution in practical applications.
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- 2023
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11. Task offloading under deterministic demand for vehicular edge computing.
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Li, Haotian, Li, Xujie, and Shen, Fei
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EDGE computing ,INTERIOR-point methods ,UPLOADING of data - Abstract
In vehicular edge computing (VEC) networks, the rapid expansion of intelligent transportation and the corresponding enormous numbers of tasks bring stringent requirements on timely task offloading. However, many tasks typically appear within a short period rather than arriving simultaneously, which makes it difficult to realize effective and efficient resource scheduling. In addition, some key information about tasks could be learned due to the regular data collection and uploading processes of sensors, which may contribute to developing effective offloading strategies. Thus, in this paper, we propose a model that considers the deterministic demand of multiple tasks. It is possible to generate effective resource reservations or early preparation decisions in offloading strategies if some feature information of the deterministic demand can be obtained in advance. We formulate our scenario as a 0‐1 programming problem to minimize the average delay of tasks and transform it into a convex form. Finally, we proposed an efficient optimal offloading algorithm that uses the interior point method. Simulation results demonstrate that the proposed algorithm has great advantages in optimizing offloading utility. [ABSTRACT FROM AUTHOR]
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- 2023
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12. Electronic Structure Optimization and Proton-Transfer Enhancement on Titanium Oxide-Supported Copper Nanoparticles for Enhanced Nitrogen Recycling from Nitrate-Contaminated Water.
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Liu, Zixun, Shen, Fei, Shi, Li, Tong, Qiuwen, Tang, Mu'e, Li, Yiming, Peng, Min, Jiao, Zhaojie, Jiang, Yan, Ao, Liang, Fu, Wenyang, Lv, Xiaoshu, Jiang, Guangming, and Hou, Li'an
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- 2023
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13. Development of General Practice in Communities From the Perspective of Supply and Demand.
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LI Ruran, ZHANG Yang, SHEN Fei, and GE Xuhua
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- 2023
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14. In Situ Formed Surface Layer to Improve the Air Stability of LLZTO and Its Contact with the Li Metal
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Zhang, Liang, Guo, Hong, Zhang, Qihang, Wang, Anli, Su, Yining, Chen, Yifei, Li, Yunpeng, Shen, Fei, and Han, Xiaogang
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Garnet-type Li7La3Zr2O12(LLZO) is regarded as one of the most promising solid-state electrolytes due to its good thermal stability, high mechanical strength, wide electrochemical window, and good stability against Li metal. However, Li and LLZO have poor physical contact, leading to a large interfacial resistance and poor electrochemical performance. It is recognized that LLZO is intrinsic lithiophilic. But LLZO easily reacts with H2O and CO2in air and generates Li2CO3and other inevitable surface contaminants. The contaminated surface results in poor interfacial wettability against Li metal. Herein, an air-stable surface layer is introduced to Li6.4La3Zr1.4Ta0.6O12(LLZTO) by simply reacting LLZTO with a LiPF6-based liquid electrolyte. During the reacting process, Li2CO3is removed and a lithiophilic and ion-conductive modified layer is formed. The layer helps to build a uniform and intimate contact between Li and LLZTO. The interfacial resistance is reduced to 15.675 Ω cm2, less than one fifth of that between bare LLZTO and Li. Benefiting from the favorable interface, stable Li plating and stripping can be conducted for over 1000 h at a current density of 0.22 mA cm–2. Even after being exposed to air for 3 days, the interfacial resistance of surface-modified LLZTO against Li remains as low as 36.29 Ω cm2and performs stable Li plating and stripping for 1000 h. Moreover, the quasi-solid-state Li metal batteries of Li/LLZTO/LiCoO2, Li/LLZTO/LiNi0.8Co0.1Mn0.1O2,and Li/LLZTO/LiNi0.5Mn1.5O4exhibit excellent cycling performances, which confirms the feasibility of the strategy in the practical manufacture.
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- 2023
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15. In Situ Formed Surface Layer to Improve the Air Stability of LLZTO and Its Contact with the Li Metal.
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Zhang, Liang, Guo, Hong, Zhang, Qihang, Wang, Anli, Su, Yining, Chen, Yifei, Li, Yunpeng, Shen, Fei, and Han, Xiaogang
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- 2023
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16. Task offloading under deterministic demand for vehicular edge computing
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Li, Haotian, Li, Xujie, and Shen, Fei
- Abstract
In vehicular edge computing (VEC) networks, the rapid expansion of intelligent transportation and the corresponding enormous numbers of tasks bring stringent requirements on timely task offloading. However, many tasks typically appear within a short period rather than arriving simultaneously, which makes it difficult to realize effective and efficient resource scheduling. In addition, some key information about tasks could be learned due to the regular data collection and uploading processes of sensors, which may contribute to developing effective offloading strategies. Thus, in this paper, we propose a model that considers the deterministic demand of multiple tasks. It is possible to generate effective resource reservations or early preparation decisions in offloading strategies if some feature information of the deterministic demand can be obtained in advance. We formulate our scenario as a 0‐1 programming problem to minimize the average delay of tasks and transform it into a convex form. Finally, we proposed an efficient optimal offloading algorithm that uses the interior point method. Simulation results demonstrate that the proposed algorithm has great advantages in optimizing offloading utility.
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- 2023
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17. One step hot-pressing method for hybrid Li metal anode of solid-state lithium metal batteries.
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Wang, Kaiming, Chen, Yifei, Zhang, Liang, Zhang, Qihang, Cheng, Zhi, Su, Yining, Shen, Fei, and Han, Xiaogang
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SUPERIONIC conductors ,LITHIUM cells ,POLYELECTROLYTES ,ANODES ,POLYETHYLENE oxide ,SCANNING electron microscopes ,CARBON paper - Abstract
• A 3D lithophilic carbon paper/current collector integrated Li metal anode (Li@LCP-Cu) is prepared by hot-pressing method, which can precisely control the Li content and thickness. • The in-situ formed lithiophilic layer on the surface of CP can exist stably and reduce the nucleation overpotential, inducing uniform and dense Li deposition. • 3D CP skeleton can reduce local current density to suppress dendrite growth and limit anode volume change. • The solid-state battery assembled with Li@LCP-Cu, PVDF-based polymer electrolyte and PEO functional layer exhibits the best electrochemical and safety performance. Safety issues induced by infinite anode volume change and uncontrolled lithium (Li) dendrite growth have become the biggest obstacle to the practical application of Li metal batteries. In addition, the traditional rolling method makes it difficult to manufacture thin Li foil with high mechanical strength and low Li content. Herein, a three-dimensional (3D) lithophilic carbon paper/copper (Cu) current collector hybrid anode with ultra-low Li metal content is prepared by a hot-pressing method. The highly reversible and stable lithiophilic layer LiC x formed in situ by heating/pressing treatment provides abundant nucleation sites and reduces the Li nucleation overpotential, thereby effectively suppressing Li dendrite growth. Moreover, the volume change and pulverization problems of Li metal anode during deposition/stripping also can be accommodated by the 3D skeleton. The optimization effect has been directly confirmed by in-situ optical and ex-situ scanning electron microscope observation. Therefore, highly stable performance (158.4 mA h g
−1 at 2 C after 200 cycles with a capacity retention of 95.24%) in Li@LCP-Cu||NCM811 coin cell can be achieved. Furthermore, the solid-state battery assembled with the hybrid anode, poly(vinylidene fluoride) (PVDF)-based polymer electrolyte and polyethylene oxide (PEO) interface functional layer also exhibits the best electrochemical and safety performance, which also proves that the Li@LCP-Cu anode has great potential for application in solid-state batteries. [Display omitted] [ABSTRACT FROM AUTHOR]- Published
- 2023
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18. Electronic Structure Optimization and Proton-Transfer Enhancement on Titanium Oxide-Supported Copper Nanoparticles for Enhanced Nitrogen Recycling from Nitrate-Contaminated Water
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Liu, Zixun, Shen, Fei, Shi, Li, Tong, Qiuwen, Tang, Mu’e, Li, Yiming, Peng, Min, Jiao, Zhaojie, Jiang, Yan, Ao, Liang, Fu, Wenyang, Lv, Xiaoshu, Jiang, Guangming, and Hou, Li’an
- Abstract
Electrocatalytic reduction of nitrate to NH3(NO3RR) on Cu offers sustainable NH3production and nitrogen recycling from nitrate-contaminated water. However, Cu affords limited NO3RR activity owing to its unfavorable electronic state and the slow proton transfer on its surface, especially in neutral/alkaline media. Furthermore, although a synchronous “NO3RR and NH3collection” system has been developed for nitrogen recycling from nitrate-laden water, no system is designed for natural water that generally contains low-concentration nitrate. Herein, we demonstrate that depositing Cu nanoparticles on a TiO2support enables the formation of electron-deficient Cuδ+species (0 < δ ≤ 2), which are more active than Cu0in NO3RR. Furthermore, TiO2–Cu coupling induces local electric-field enhancement that intensifies water adsorption/dissociation at the interface, accelerating proton transfer for NO3RR on Cu. With the dual enhancements, TiO2–Cu delivers an NH3-N selectivity of 90.5%, mass activity of 41.4 mg-N h gCu–1, specific activity of 377.8 mg-N h–1m–2, and minimal Cu leaching (<25.4 μg L–1) when treating 22.5 mg L–1of NO3–-N at −0.40 V, outperforming most of the reported Cu-based catalysts. A sequential NO3RR and NH3collection system based on TiO2–Cu was then proposed, which could recycle nitrogen from nitrate-contaminated water under a wide concentration window of 22.5–112.5 mg L–1at a rate of 209–630 mgNm–2h–1. We also demonstrated this system could collect 83.9% of nitrogen from NO3–-N (19.3 mg L–1) in natural lake water.
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- 2023
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19. Thermoelastic rotating contact of an FGM coating with temperature-dependent and arbitrary varying properties
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Zhou, JiaLin, Shen, Fei, Liu, Jing, El-Borgi, Sami, and Ke, LiaoLiang
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This paper investigates the frictional thermoelastic contact of a rigid spherical punch and functionally graded material (FGM) coated half-space with arbitrarily varying material properties. These material parameters include the elastic modulus, Poisson’s ratio, heat conduction parameter, and thermal expansion coefficient. The material parameters of the FGM coating and half-space are assumed to be temperature dependent. The spherical punch is rotated in the FGM-coated half-space at a constant angular speed. The generated frictional heat is related to the friction coefficient, contact radius, angular velocity, and contact pressure. A theoretical formula for the thermoelastic rotating contact problem is established and solved using the finite element method. The main objective of this paper is to investigate the effects of temperature dependence, gradient index, friction coefficient, angular velocity, and gradient form on the surface temperature and stresses.
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- 2023
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20. Electrode structure enabling dendrite inhibition for high cycle stability quasi-solid-state lithium metal batteries
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Wang, Kaiming, Yu, Ao, Zhou, Zhiyi, Shen, Fei, Li, Manni, Zhang, Liang, Guo, Weichang, Chen, Yifei, Shi, Le, and Han, Xiaogang
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Novel structured lithium metal anodes with vertically arrayed holes and insulating layer are fabricated by in-situ blade coating and mechanical punching to modulate the electric field/Li+gradient for the excellent electrochemical performance of quasi-solid-state batteries.
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- 2023
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21. A bulked segregant analysis tool for out-crossing species (BSATOS) and QTL-based genomics-assisted prediction of complex traits in apple.
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Shen, Fei, Bianco, Luca, Wu, Bei, Tian, Zhendong, Wang, Yi, Wu, Ting, Xu, Xuefeng, Han, Zhenhai, Velasco, Riccardo, Fontana, Paolo, and Zhang, Xinzhong
- Abstract
[Display omitted] • The BSATOS takes advantage of using haplotypes and markers with different segregation patterns to identify QTLs. • A novel integrated strategy was developed to conduct genomics-assisted prediction (GAP) in out-crossing species. • GAP models were successfully developed for apple fruit weight, ripening date, and soluble solid content. Genomic heterozygosity, self-incompatibility, and rich-in somatic mutations hinder the molecular breeding efficiency of outcrossing plants. We attempted to develop an efficient integrated strategy to identify quantitative trait loci (QTLs) and trait-associated genes, to develop gene markers, and to construct genomics-assisted prediction (GAP) modes. A novel protocol, bulked segregant analysis tool for out-crossing species (BSATOS), is presented here, which is characterized by taking full advantage of all segregation patterns (including AB × AB markers) and haplotype information. To verify the effectiveness of the protocol in dealing with the complex traits of outbreeding species, three apple cross populations with 9,654 individuals were adopted. By using BSATOS, 90, 60, and 77 significant QTLs were identified successfully and candidate genes were predicted for apple fruit weight (FW), fruit ripening date (FRD), and fruit soluble solid content (SSC), respectively. The gene-based markers were developed and genotyped for 1,396 individuals in a training population, including 145 Malus accessions and 1,251 F1 plants of the three full-sib families. GAP models were trained using marker genotype effect estimates of the training population. The prediction accuracy was 0.7658, 0.6455, and 0.3758 for FW, FRD, and SSC, respectively. The BSATOS and GAP models provided a convenient and efficient methodology for candidate gene mining and molecular breeding in out-crossing plant species. The BSATOS pipeline can be freely downloaded from: https://github.com/maypoleflyn/BSATOS. [ABSTRACT FROM AUTHOR]
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- 2022
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22. Sea cucumber (Acaudina leucoprocta) peptides exhibit anti-aging effect in Drosophila melanogaster via regulation of microbiota dysbiosis and metabolic disorder.
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Wang, Qianqian, Zhang, Junhui, Shen, Fei, Du, Juan, and Feng, Fengqin
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DROSOPHILA melanogaster ,INTESTINAL barrier function ,AGING prevention ,METABOLIC disorders ,PEPTIDES ,SEA cucumbers ,CAENORHABDITIS - Abstract
As the population ages, the pursuit of extended lifespan and improved healthspan has gained significance. This study assessed the anti-aging properties of sea cucumber peptides derived from Acaudina leucoprocta (SCP) through microbiome and metabolome analyses in Drosophila melanogaster. Supplementation with 0.2%, 0.4%, 0.6%, and 0.8% of SCP significantly boosted the survival rate and extended the mean and median lifespans in both male and female flies. Among them, 0.6% SCP treatment extended the mean and median lifespans of male flies by 21.01% and 25.48 %, which showed the most prominent lifespan-prolonging effect. Moreover, SCP enhanced the healthspan of male flies by improving their climbing ability, intestinal barrier function, and memory performance. Additionally, SCP boosted the survival rate of flies subjected to oxidative, starvation, and heat stress, with no significant effect observed under cold stress conditions. The lifespan-extension effect of SCP remained unaffected by dietary restriction, but was partially inhibited when provided with antibiotic-supplemented food. SCP modulated microbiota with increased the abundance of Lactobacillus , Rhodococcus , and Propioniciclava and decreased Acetobacter , Achromobacter , Pedobacter , and norank_f_ Saprospiraceae, which closely related with lifespan-extension effect. Furthermore, SCP induced a metabolic profile in 30-day-old flies more akin to that of 3-day-old flies, impacted 13 significantly regulated metabolites associated with amino acid, nucleotide, and carbohydrate metabolisms. These findings highlight SCP intervention as a promising anti-aging strategy. [Display omitted] [ABSTRACT FROM AUTHOR]
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- 2024
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23. A TOF spectrometer for neutron spectral measurements in a wide energy range base on a fast ionization chamber containing 6Li-235U
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Zhou, Bin, Wang, Songlin, Hu, Zhiliang, Shen, Fei, Yi, Tiancheng, Zeng, Zhirong, Yu, Quanzhi, Yin, Wen, Ruan, Xichao, and Liang, Tianjiao
- Abstract
ABSTRACTTo measure the neutron spectra in a wide energy range at the China Spallation Neutron Source (CSNS), a time of flight (TOF) neutron spectrometer based on a fast ionization chamber (FIC) containing 6Li and 235U has been developed. Verification experiments have been performed at the BL09 test beam line at the CSNS, which demonstrated that the measured neutron spectra, analyzed with a spectrum-splicing technique, ranging from sub-meV to 10 keV with a limited flight path. Comparisons demonstrated that the integral thermal neutron fluence obtained by the TOF spectrometer and the cadmium difference activation measurements used were in good agreement. Moreover, the measured neutron spectra agreed well with the Monte Carlo simulations. This shows that the developed equipment and the measurement methods are reliable.
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- 2023
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24. Irisin ameliorates age‐associated sarcopenia and metabolic dysfunction
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Guo, Mingwei, Yao, Jing, Li, Jin, Zhang, Jun, Wang, Dongmei, Zuo, Hui, Zhang, Yi, Xu, Bo, Zhong, Yinzhao, Shen, Fei, Lu, Jian, Ding, Shuzhe, Hu, Cheng, Xu, Lingyan, Xiao, Junjie, and Ma, Xinran
- Abstract
Age‐associated sarcopenia is characterized of progressed loss of skeletal muscle power, mass, and function, which affects human physical activity and life quality. Besides, accompanied with sarcopenia, aged population also faces a series of metabolic dysfunctions. Irisin, the cleaved form of fibronectin type III domain‐containing protein 5 (FNDC5), is a myokine induced by exercise and has been shown to exert multiple beneficial effects on health. The goal of the study is to investigate the alterations of Fndc5/irisin in skeletal muscles during ageing and whether irisin administration could ameliorate age‐associated sarcopenia and metabolic dysfunction. The mRNA and protein levels of FNDC5/irisin in skeletal muscle and serum from 2‐ and 24‐month‐old mice or human subjects were analysed using qRT‐PCR and western blot. FNDC5/irisin knockout mice were generated to investigate the consequences of FNDC5/irisin deletion on skeletal muscle mass, as well as morphological and molecular changes in muscle during ageing via histological and molecular analysis. To identify the therapeutic effects of chronic irisin treatment in mice during ageing, in vivointraperitoneal administration of 2 mg/kg recombinant irisin was performed three times per week in ageing mice (14‐month‐old) for 4 months or in aged mice (22‐month‐old) for 1 month to systematically investigate irisin's effects on age‐associated sarcopenia and metabolic performances, including grip strength, body weights, body composition, insulin sensitivity, energy expenditure, serum parameters and phenotypical and molecular changes in fat and liver. We showed that the expression levels of irisin, as well as its precursor Fndc5, were reduced at mRNA and protein expression levels in muscle during ageing. In addition, via phenotypic analysis of FNDC5/irisin knockout mice, we found that FNDC5/irisin deficiency in aged mice exhibited aggravated muscle atrophy including smaller grip strength (−3.23%, P< 0.05), muscle weights (quadriceps femoris [QU]: −20.05%; gastrocnemius [GAS]: −17.91%; tibialis anterior [TA]: −19.51%, all P< 0.05), fibre size (QU: P< 0.01) and worse molecular phenotypes compared with wild‐type mice. We then delivered recombinant irisin protein intraperitoneally into ageing or aged mice and found that it could improve sarcopenia with grip strength (+18.42%, P< 0.01 or +13.88%, P< 0.01), muscle weights (QU: +9.02%, P< 0.01 or +16.39%, P< 0.05), fibre size (QU: both P< 0.05) and molecular phenotypes and alleviated age‐associated fat tissues expansion, insulin resistance and hepatic steatosis (all P< 0.05), accompanied with altered gene signatures. Together, this study revealed the importance of irisin in the maintenance of muscle physiology and systematic energy homeostasis during ageing and suggested a potent therapeutic strategy against age‐associated metabolic diseases via irisin administration.
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- 2023
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25. Inverse-GMM: A Latency Distribution Shaping Method for Industrial Cooperative Deep Learning Systems
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Qin, Fei, Xiao, Yucong, Sun, Xian, Dai, Xuewu, Zhang, Wuxiong, and Shen, Fei
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The front deployed deep learning is a promising technology of the next generation industrial applications, which can extract essential information from high dimension sensors. However, part of these heavy computation tasks at resource constrained front devices have to be offloaded to the edge or cloud devices, which forms the cooperative deep learning system through the exchange of intermediate data. The inference efficiency of cooperative deep learning system will then be highly correlated with the communication latency caused by the non-stationary industrial multipath-rich fading channel. This paper proposes a novel method to control the distribution of communications latency, which is able to support efficient cooperative deep learning architecture in the harsh industrial environment. The proposed method is essentially an inverse process of Gaussian Mixture Model (GMM), which adjusts latency samples to approach the given arbitrary shape function. To achieve this objective, a new variation of Expectation-Maximization (EM) algorithm in analytical domain is derived to decompose arbitrary distribution shape with multiple Gaussian kernels and an optimized stochastic resource allocation algorithm is proposed to approximate each Gaussian kernels. The performance of proposed method is verified by both classical Rician channel model and field measured industrial fading channel responses.
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- 2023
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26. Investigating Shift Equivalence of Convolutional Neural Networks in Industrial Defect Segmentation
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Qu, Zhen, Tao, Xian, Shen, Fei, Zhang, Zhengtao, and Li, Tao
- Abstract
In industrial defect segmentation tasks, while pixel accuracy and Intersection over Union (IoU) are commonly employed metrics to assess segmentation performance, the output consistency (also referred to as equivalence) of the model is often overlooked. Even a small shift in the input image can yield significant fluctuations in the segmentation results. Existing methodologies primarily focus on data augmentation or antialiasing to enhance the network’s robustness against translational transformations, but their shift equivalence performs poorly on the test set or is susceptible to nonlinear activation functions. In addition, the variations in boundaries resulting from the translation of input images are consistently disregarded, thus imposing further limitations on the shift equivalence. In response to this particular challenge, a novel pair of downsampling/upsampling layers called component attention polyphase sampling (CAPS) is proposed as a replacement for the conventional sampling layers in CNNs. To mitigate the effect of image boundary variations on the equivalence, an adaptive windowing module is designed in CAPS to adaptively filter out the border pixels of the image. Furthermore, a component attention module is proposed to fuse all downsampled features to improve the segmentation performance. The experimental results on the micro surface defect (MSD) dataset and four real-world industrial defect datasets demonstrate that the proposed method exhibits higher equivalence and segmentation performance compared to other state-of-the-art methods. Our code will be available at
https://github.com/xiaozhen228/CAPS .- Published
- 2023
- Full Text
- View/download PDF
27. Fractionation of poplar through solid acid pretreatment assisted by mild alkali-1-butanol immersion to effectively produce xylose, glucose, and solid lignin
- Author
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Chen, Yang, Qi, Wei, Shakeel, Usama, Liang, Cuiyi, Wang, Wen, Hu, Yunzi, Wang, Zhongming, Yuan, Zhenhong, Shen, Fei, and Wang, Qiong
- Abstract
The efficient fractionation and recovery of lignocellulosic biomass (LCB) constituents, hemicellulose, cellulose, and lignin, are ideal for LCB utilization. In this study, we prepared a solid acid catalyst (SPS120-40) with high acid density using polystyrene resin (PS) as precursor. The synthesized catalyst was characterized by XPS, 13C NMR, TG-FTIR-MS, and so on to investigate its structural properties and thermal stability. During process optimization using FeCl3-assisted SPS120-40, a total of 78.9% xylose yield with 96.6% monosaccharide selectivity was achieved. Moreover, the catalyst showed extraordinary catalytic activity until five runs without significant loss in xylose yield. The pretreated residue was further treated with NaOH-1-butanol to effectively remove the lignin deposited on the residue surface and eventually 89.5% hydrolysis rate was obtained. At the same time, 64.4% lignin was obtained in the residue of enzymatic hydrolysis. This work provides important guidance for utilizing the whole components of lignocellulose.
- Published
- 2023
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28. A trusted multi-task distribution mechanism for Internet of vehicles based on smart contract
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Li, Xujie, Xu, Yuan, Tang, Jing, Sun, Ying, Fan, Shaoshuai, and Shen, Fei
- Abstract
In this paper, a trusted multi-task distribution mechanism for Internet of Vehicles based on smart contract is proposed to improve the security and efficiency for the task distribution in Internet of Vehicles. Firstly, a three-tier trusted multi-task distribution framework is presented based on smart contract. The smart contract will be triggered by the task request. As the important part of the smart contract, the task distribution algorithm is stored on the blockchain and run automatically. In the process of the task distribution, the cost of the task distribution and the system stability play a critical role. Therefore, the task distribution problem is formulated to minimize the cost of the task distribution whilst maintaining the stability of the system based on Lyapunov theorem. Unfortunately, this problem is a mixed integer nonlinear programming problem with NP-hard characteristics. To tackle this, the optimization problem is decomposed into two sub problems of computing resource allocation and task distribution decision, and an effective task distribution algorithm is proposed. Simulation results show that the proposed algorithm can effectively improves system performance.
- Published
- 2023
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29. A UV cross-linked gel polymer electrolyte enabling high-rate and high voltage window for quasi-solid-state supercapacitors
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Bai, Yuge, Yang, Chao, Yuan, Boheng, Li, Hongjie, Chen, Weimeng, Yin, Haosen, Zhao, Bin, Shen, Fei, and Han, Xiaogang
- Abstract
The composite membrane with porous structure applied in gel polymer electrolytes is fabricated by UV cross-linking PVDF-HFP with PAN assisted by N-CQDs and TiO2, enabling supercapacitors with superb electrochemical performance.
- Published
- 2023
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30. Bandage contact lens soaked in 0.1% diclofenac to relieve early postoperative pain and foreign body sensation after transepithelial photorefractive keratectomy
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Wang, Yuan, Shen, Fei, Sun, Weiyang, Wang, Qinmei, and Zhao, Xiangyang
- Abstract
Purpose To study the effects of a bandage contact lens immersed in 0.1% diclofenac on pain management for patients undergoing transepithelial photorefractive keratectomy (TPRK).Methods In a prospective, comparative, contralateral, randomized, double-masked study, we assessed a total of 51 patients. The eyes of each patient were randomly divided into two groups. After TPRK, a normal soft bandage contact lens was placed on one eye as the control group, and a bandage contact lens soaked in diclofenac was placed on the other eye as the experimental group. When the bandage contact lens was not removed, postoperative pain and other ocular discomforts were compared at 2, 18, and 24 h and 2, 3, 4, and 5 postoperative days. Patients were then examined after 1 month. Visual acuity and subepithelial haze were also evaluated.Results The mean pain score was 2.69 ± 1.96 in the control group, which was significantly higher than that in the experimental group, which received the diclofenac-soaked bandage contact lens at 2 postoperative hours. The statistical difference between the two groups’ mean foreign body sensation at 2 postoperative hours was detected (p = 0.035). No differences were detected between the two groups’ subepithelial haze scores or visual acuity.Conclusion A bandage contact lens soaked in 0.1% diclofenac solution can be used as a potential drug-delivery system to relieve early postoperative pain and foreign body sensation after TPRK.
- Published
- 2022
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31. Sea cucumber (Acaudina leucoprocta) peptides exhibit anti-aging effect in Drosophila melanogastervia regulation of microbiota dysbiosis and metabolic disorder
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Wang, Qianqian, Zhang, Junhui, Shen, Fei, Du, Juan, and Feng, Fengqin
- Abstract
As the population ages, the pursuit of extended lifespan and improved healthspan has gained significance. This study assessed the anti-aging properties of sea cucumber peptides derived from Acaudina leucoprocta(SCP) through microbiome and metabolome analyses in Drosophila melanogaster. Supplementation with 0.2%, 0.4%, 0.6%, and 0.8% of SCP significantly boosted the survival rate and extended the mean and median lifespans in both male and female flies. Among them, 0.6% SCP treatment extended the mean and median lifespans of male flies by 21.01% and 25.48 %, which showed the most prominent lifespan-prolonging effect. Moreover, SCP enhanced the healthspan of male flies by improving their climbing ability, intestinal barrier function, and memory performance. Additionally, SCP boosted the survival rate of flies subjected to oxidative, starvation, and heat stress, with no significant effect observed under cold stress conditions. The lifespan-extension effect of SCP remained unaffected by dietary restriction, but was partially inhibited when provided with antibiotic-supplemented food. SCP modulated microbiota with increased the abundance of Lactobacillus, Rhodococcus, and Propioniciclavaand decreased Acetobacter, Achromobacter, Pedobacter, and norank_f_Saprospiraceae, which closely related with lifespan-extension effect. Furthermore, SCP induced a metabolic profile in 30-day-old flies more akin to that of 3-day-old flies, impacted 13 significantly regulated metabolites associated with amino acid, nucleotide, and carbohydrate metabolisms. These findings highlight SCP intervention as a promising anti-aging strategy.
- Published
- 2024
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32. A Simple and Efficient Strategy for Ameliorating Li/LLZO Interfacial Contact
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Liu, Jiawei, Guo, Weichang, Guo, Hong, Xu, Chenliang, Zhang, Liang, Chen, Yifei, Shen, Fei, and Han, Xiaogang
- Abstract
Li7La3Zr2O12(LLZO) is considered as one of the most promising solid-state electrolytes for lithium (Li) metal batteries due to its wide electrochemical window and good electrochemical stability against Li metal. However, undesired lithium carbonate (Li2CO3) contamination cannot be avoided and it turns the LLZO surface to a lithophobic surface. The consequent large interfacial resistance limits its electrochemical performances. Herein, a drop-casting method using metal oxides is introduced to remove Li2CO3and improve the interfacial contact between Li metal and Li6.4La3Zr1.4Ta0.6O12(LLZTO). For example, due to the reduction and alloying reactions between gallium oxide (Ga2O3) and molten Li, a Li-Ga-O layer is formed, which exhibits an excellent wetting property on the LLZTO surface. During the alloying process of the lithiophilic Li-Ga-O interlayer, it breaks the Li2CO3contamination layer into fragments by alloying expansion force, allowing the Li-Ga-O interlayer to spread to the LLZTO surface. Benefiting from the improved interfacial contact, the interfacial resistance decreases from 1789 to 4.35 Ω/cm2. The Li symmetric cell cycles over 2000 hs under 0.235 mA/cm2and the Li|Ga2O3@LLZTO|LiCoO2full cell works for 100 cycles at room temperature.
- Published
- 2022
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33. A Simple and Efficient Strategy for Ameliorating Li/LLZO Interfacial Contact.
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Liu, Jiawei, Guo, Weichang, Guo, Hong, Xu, Chenliang, Zhang, Liang, Chen, Yifei, Shen, Fei, and Han, Xiaogang
- Published
- 2022
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34. Design and development of engineering supervision management information system
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Powell, Warwick, Tolba, Amr, Shen, Fei, Cai, Hualong, Wang, Qisheng, and Zhuang, Yiyan
- Published
- 2022
- Full Text
- View/download PDF
35. BRE12-158: A Postneoadjuvant, Randomized Phase II Trial of Personalized Therapy Versus Treatment of Physician's Choice for Patients With Residual Triple-Negative Breast Cancer.
- Author
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Schneider, Bryan P, Jiang, Guanglong, Ballinger, Tarah J, Shen, Fei, Chitambar, Christopher, Nanda, Rita, Falkson, Carla, Lynce, Filipa C, Gallagher, Christopher, Isaacs, Claudine, Blaya, Marcelo, Paplomata, Elisavet, Walling, Radhika, Daily, Karen, Mahtani, Reshma, Thompson, Michael A, Graham, Robert, Cooper, Maureen E, Pavlick, Dean C, and Albacker, Lee A
- Published
- 2022
- Full Text
- View/download PDF
36. A core–shell Fe3O4@NH2-MIL-101(Cr) composite material for efficient removal of formaldehyde
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Liu, Yan, Xie, Shuqi, He, Jinsong, He, Yan, Luo, Ling, Wang, Lilin, Chen, Chao, Shen, Fei, Deng, Shihuai, and Zhang, Yanzong
- Abstract
Graphical abstract: Effective adsorption removal of HCHO with FNM-0.2
- Published
- 2022
- Full Text
- View/download PDF
37. Using ultrasonic sensors to study sound attenuation of thermal insulation materials
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Pan, Lijia, Chen, Yiwei, He, Xiaofang, Shen, Fei, and Qiu, Fei
- Published
- 2022
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38. Cross-national variation in political network size, distribution, and prediction.
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Eveland, William P. and Shen, Fei
- Subjects
SOCIAL networks ,SOCIAL sciences education ,SIZE ,POLITICAL participation ,FORECASTING - Abstract
• Average political network size varies cross-nationally, but is always right skewed. • Socio-demographic predictors have limited impact on political network size. • Political network size is associated with factors such as political involvement and engagement. • There is often cross-national variation in the predictors of political network size. Network size has a fundamental influence on other network properties. As studies of social network size have accumulated beyond the U.S. and Western Europe, diversity in the networks examined and methods used to construct size estimates have hindered the ability to make direct cross-national comparisons. We employ data from a summary political discussion network size measure in 17 surveys conducted in 15 countries between 2012 and 2018. We offer improved cross-national data on political network size distributions and estimate aggregate and country-specific models to understand the factors, both social and political, that predict political network size within countries. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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- View/download PDF
39. Construction of Conductive Polymer Coatings onto Flexible PDMS Foam Composites with Exceptional Mechanical Robustness for Sensitive Strain Sensing Applications
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Nie, Feng, Gu, Ya‐Li, Zhao, Li, Li, Long‐Tao, Shen, Fei‐Xiang, Song, Jiang, Liu, Jun, Zhang, Guo‐Dong, Gao, Jie‐Feng, Song, Pingan, Shi, Yongqian, and Tang, Long‐Cheng
- Abstract
Flexible piezoresistive‐sensing materials with high sensitivity and stable sensing signals are highly required to meet the accurate detecting requirement for human motion. Herein, a conductive poly(3,4‐ethylenedioxythiophene): poly(styrenesulfonate) / polydimethylsiloxane foam (P:P@p‐PSF) composite with strong interfacial action is designed. The porous structures and good interface combination not only show outstanding mechanical flexibility and reliability but also possess high sensitivity at a relatively wide strain range. The P:P@p‐PSF sensor achieves extreme sensitivity (Gauge Factor) of 6.25 in the subtle strain range of 1%–8%. Furthermore, the sensor forms a highly interconnected conductive network induced by the serious deformation of elastic‐interconnect pores, thus providing extremely sensitive sensing behavior for a relatively wide strain range (97.4% resistance change rate at 60% compressive strain). Moreover, the sensor presents repeatable stability and good thermal adaptation, which would meet the critical requirements of subtle vital signs, human motion monitoring, and so on. This work supplies insight into the design of a new flexible sensor material to overcome the weak interface problem and the flexible mismatch between conductive filler and matrix, showing great application potential in the field of electronic skin. The surface of PDMS foam is activated by oxygen plasma treatment technology, and then the PEDOT:PSS firmly coats the pore surface of the foam via forming sulfonic ester covalent bonds and hydrogen bonds. The obtained conductive foam composites by combining these two flexible materials show excellent piezoresistivity with high sensitivity and good cyclic reliability.
- Published
- 2024
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40. Cooled mid-infrared unobscured three-mirror system with an intermediate image plane using freeform surfaces
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Liu, Jennifer, Tan, Jiubin, Luo, Xiangang, Huang, Ming, Kong, Lingbao, Zhang, Dawei, Yu, Jun, Zhanshan, Wang, Shen, Zhengxiang, Sheng, Pengfeng, Shen, Fei, and Ye, Jingfei
- Published
- 2022
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41. Crystalline tetra-aniline with chloride interactions towards a biocompatible supercapacitorElectronic supplementary information (ESI) available. See DOI: 10.1039/d1mh01081f
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Tong, Xiaoling, Sheng, Guan, Yang, Dongzi, Li, Shuo, Lin, Cheng-Wei, Zhang, Wei, Chen, Zhihui, Wei, Chaohui, Yang, Xianzhong, Shen, Fei, Shao, Yanyan, Wei, Hui, Zhu, Yihan, Sun, Jingyu, Kaner, Richard B., and Shao, Yuanlong
- Abstract
Recent advances in wearable and implantable electronics have increased the demand for biocompatible integrated energy storage systems. Conducting polymers, such as polyaniline (PANi), have been suggested as promising electrode materials for flexible biocompatible energy storage systems, based on their intrinsic structural flexibility and potential polymer chain compatibility with biological interfaces. However, due to structural disorder triggering insufficient electronic conductivity and moderate electrochemical stability, PANi still cannot fully satisfy the requirements for flexible and biocompatible energy storage systems. Herein, we report a biocompatible physiological electrolyte activated flexible supercapacitor encompassing crystalline tetra-aniline (c-TANi) as the active electrode material, which significantly enhances the specific capacitance and electrochemical cycling stability with chloride electrochemical interactions. The crystallization of TANi endows it with sufficient electronic conductivity (8.37 S cm−1) and a unique Cl−dominated redox charge storage mechanism. Notably, a fully self-healable and biocompatible supercapacitor has been assembled by incorporating polyethylene glycol (PEG) with c-TANi as a self-healable electrode and a ferric-ion cross-linked sodium polyacrylate (Fe3+-PANa)/0.9 wt% NaCl as a gel electrolyte. The as-prepared device exhibits a remarkable capacitance retention even after multiple cut/healing cycles. With these attractive features, the c-TANi electrode presents a promising approach to meeting the power requirements for wearable or implantable electronics.
- Published
- 2022
- Full Text
- View/download PDF
42. Assembly of Nanofluidic MXene Fibers with Enhanced Ionic Transport and Capacitive Charge Storage by Flake Orientation.
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Li, Shuo, Fan, Zhaodi, Wu, Guiqing, Shao, Yanyan, Xia, Zhou, Wei, Chaohui, Shen, Fei, Tong, Xiaoling, Yu, Jinchao, Chen, Kang, Wang, Menglei, Zhao, Yu, Luo, Zhipu, Jian, Muqiang, Sun, Jingyu, Kaner, Richard B., and Shao, Yuanlong
- Published
- 2021
- Full Text
- View/download PDF
43. Rational designed of PVDF membrane based on surface modification of εPL anchored by PC for crude oil emulsion separation.
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Liu, Yan, Guo, Yunfei, Wang, Lilin, He, Jinsong, Luo, Ling, Tang, Weixu, Huang, Chengyi, Chen, Chao, Shen, Fei, and Zhang, Yanzong
- Abstract
For high-viscosity wastewater containing crude oil, the membrane material is easily clogged with contaminations, resulting in decreased flux and potentially loss of separation ability. In this study, a superhydrophilic/underwater superoleophobic PVDF membrane (PVDF-PC-εPL) was designed by the self-polymerization of proanthocyanidins (PC) and the grafting reaction of ε-polylysine (εPL), which showed a rough micro-nano structure without adding the inorganic particles. The PVDF-PC-εPL membrane displayed outstanding self-cleaning ability for high-viscosity crude oil, and the separation efficiency of the crude oil-in-water emulsion could be greater than 99.4%. The underwater oil contact angle (UWOCA) of the PVDF-PC-εPL membrane was 165°, after the PVDF-PC-εPL membrane had been exposed to air or water for 6 weeks, or soaked in different pH or seawater for 24 h, the UWOCA remained above 154° and the water contact angle was always 0°. The modification method on the PVDF membrane proposed in this study offers a fresh perspective and choice for preparing the oil-water separation materials. • ε-Polylysine was first used to fabricate oil-water separation materials. • Superhydrophilic coating was prepared by self-polymerization and grafting reaction. • Organic micro-nano structures were constructed without adding inorganic nanoparticles. • The modified membrane had excellent antifouling and self-cleaning properties for crude oil. • The modified membrane can efficiently separate oil-in-water emulsion [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
44. Effect of Co-Addition of Ag and Cu on Mechanical Properties of Sn–5Sb Lead-Free Solder
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Yuan, Biao, Liang, Zhimin, Yang, Zongyuan, Shen, Fei, Xu, Da, Wang, Liwei, Wei, Shaowei, and Wang, Dianlong
- Abstract
Sn–Sb lead-free solders are considered to substitute the tin–lead solders due to their great mechanical properties. At room temperature, the mechanical properties of Ni/Au/Sn–5Sb/Au/Ni and Ni/Au/Sn–5Sb–0.3Ag–0.05Cu/Au/Ni linear solder joints were investigated by nanoindentation experiments at different loads. The results showed that the Sn–Sb intermetallic compound (IMC) was distributed in the β-Sn matrix in Ni/Au/Sn–5Sb/Au/Ni solder joints. Co-addition of Cu and Ag resulted in the formation of the rod-shaped Cu6Sn5and the fine granular Ag3Sn IMCs. At the same load and loading/unloading rate, the indentation depth and residual indentation morphologies of Ni/Au/Sn–5Sb–0.3Ag–0.05Cu/Au/Ni solder joints were smaller than those of Ni/Au/Sn–5Sb/Au/Ni solder joints. The hardness of the two kinds of solder joints decreased with the increase in load, while the Young’s modulus was independent of load. In addition, compared to the Ni/Au/Sn–5Sb/Au/Ni solder joints, the hardness, Young’s modulus and stress exponents of Ni/Au/Sn–5Sb–0.3Ag–0.05Cu/Au/Ni solder joints achieved an improvement due to the co-addition of Ag and Cu.
- Published
- 2021
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- View/download PDF
45. Inverted U-Shaped Associations between Glycemic Indices and Serum Uric Acid Levels in the General Chinese Population: Findings from the China Cardiometabolic Disease and Cancer Cohort (4C) Study.
- Author
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ZHU, Yuan Yue, ZHENG, Rui Zhi, WANG, Gui Xia, CHEN, Li, SHI, Li Xin, SU, Qing, XU, Min, XU, Yu, CHEN, Yu Hong, YU Xue, Feng, YAN, Li, WANG Tian, Ge, ZHAO, Zhi Yun, QIN, Gui Jun, WAN, Qin, CHEN, Gang, GAO, Zheng Nan, SHEN, Fei Xia, LUO, Zuo Jie, and QIN, Ying Fen
- Subjects
GLYCEMIC index ,URIC acid ,HEART metabolism disorders ,CHINESE people ,GLUCOSE tolerance tests ,POPULATION of China - Abstract
The relationship between serum uric acid (SUA) levels and glycemic indices, including plasma glucose (FPG), 2-hour postload glucose (2h-PG), and glycated hemoglobin (HbA1c), remains inconclusive. We aimed to explore the associations between glycemic indices and SUA levels in the general Chinese population. The current study was a cross-sectional analysis using the first follow-up survey data from The China Cardiometabolic Disease and Cancer Cohort Study. A total of 105,922 community-dwelling adults aged ≥ 40 years underwent the oral glucose tolerance test and uric acid assessment. The nonlinear relationships between glycemic indices and SUA levels were explored using generalized additive models. A total of 30,941 men and 62,361 women were eligible for the current analysis. Generalized additive models verified the inverted U-shaped association between glycemic indices and SUA levels, but with different inflection points in men and women. The thresholds for FPG, 2h-PG, and HbA1c for men and women were 6.5/8.0 mmol/L, 11.0/14.0 mmol/L, and 6.1/6.5, respectively (SUA levels increased with increasing glycemic indices before the inflection points and then eventually decreased with further increases in the glycemic indices). An inverted U-shaped association was observed between major glycemic indices and uric acid levels in both sexes, while the inflection points were reached earlier in men than in women. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
46. Dendrite-Suppressing Separator with High Thermal Stability Modified by Beaded-Chain-Like Polyimide Coating for a Li Metal Anode
- Author
-
Yin, Yuting, Wang, Kaiming, Shen, Fei, and Han, Xiaogang
- Abstract
Dendritic Li growth is the root hurdle against the implementation of a Li metal anode because it brings safety issues and unsatisfactory efficiency. In this work, a beaded-chain-like polyimide (PI) coating is designed on the commercial polyethylene (PE) separator to suppress the Li dendrite. Owing to the compactly stacking structure and high Li-ion absorption of the PI coating, the wettability of the prepared PI-PE separator is improved and a Li-ion-rich layer with uniform Li-ion transfer channels forms on the surface of the Li metal anode. Therefore, the planar Li deposition rather than dendrite growth has been achieved using this custom separator. The life spans of Cu||PI-PE||Li half-cells have been extended to 7 and 4 times longer than that of Cu||PE||Li half-cells at a current density of 1 mA/cm2with deposition capacities of 0.5 and 1 mA h/cm2, respectively. Besides suppressing Li dendrites, the multifunctional PI-PE separator also delivers a higher thermal stability to 120 °C than commercial PE and Al2O3-PE separators. This facile approach provides a feasible strategy to realize smooth lithium deposition, and the fundamental mechanism underlying the combination of pore structure and surface chemistry may lead to new approaches to tackle the dendritic problem of Li deposition.
- Published
- 2021
- Full Text
- View/download PDF
47. Assembly of Nanofluidic MXene Fibers with Enhanced Ionic Transport and Capacitive Charge Storage by Flake Orientation
- Author
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Li, Shuo, Fan, Zhaodi, Wu, Guiqing, Shao, Yanyan, Xia, Zhou, Wei, Chaohui, Shen, Fei, Tong, Xiaoling, Yu, Jinchao, Chen, Kang, Wang, Menglei, Zhao, Yu, Luo, Zhipu, Jian, Muqiang, Sun, Jingyu, Kaner, Richard B., and Shao, Yuanlong
- Abstract
MXenes are an emerging class of highly conductive two-dimensional (2D) materials with electrochemical storage features. Oriented macroscopic Ti3C2Txfibers can be fabricated from a colloidal 2D nematic phase dispersion. The layered conductive Ti3C2Txfibers are ideal candidates for constructing high-speed ionic transport channels to enhance the electrochemical capacitive charge storage performance. In this work, we assemble Ti3C2Txfibers with a high degree of flake orientation by a wet spinning process with controlled spinning speeds and morphology of the spinneret. In addition to the effects of cross-linking of magnesium ions between Ti3C2Txflakes, the electronic conductivity and mechanical strength of the as-prepared fibers have been improved to 7200 S cm–1and 118 MPa, respectively. The oriented Ti3C2Txfibers present a volumetric capacitive charge storage capability of up to 1360 F cm–3even in a Mg-ion based neutral electrolyte, with contributions from both nanofluidic ion transport and Mg-ion intercalation pseudocapacitance. The oriented 2D Ti3C2Txdriven nanofluidic channels with great electronic conductivity and mechanical strength endows the MXene fibers with attributes for serving as conductive ionic cables and active materials for fiber-type capacitive electrochemical energy storage, biosensors, and potentially biocompatible fibrillar tissues.
- Published
- 2021
- Full Text
- View/download PDF
48. Cyrius: accurate CYP2D6genotyping using whole-genome sequencing data
- Author
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Chen, Xiao, Shen, Fei, Gonzaludo, Nina, Malhotra, Alka, Rogert, Cande, Taft, Ryan J., Bentley, David R., and Eberle, Michael A.
- Abstract
Responsible for the metabolism of ~21% of clinically used drugs, CYP2D6is a critical component of personalized medicine initiatives. Genotyping CYP2D6is challenging due to sequence similarity with its pseudogene paralog CYP2D7and a high number and variety of common structural variants (SVs). Here we describe a novel bioinformatics method, Cyrius, that accurately genotypes CYP2D6using whole-genome sequencing (WGS) data. We show that Cyrius has superior performance (96.5% concordance with truth genotypes) compared to existing methods (84–86.8%). After implementing the improvements identified from the comparison against the truth data, Cyrius’s accuracy has since been improved to 99.3%. Using Cyrius, we built a haplotype frequency database from 2504 ethnically diverse samples and estimate that SV-containing star alleles are more frequent than previously reported. Cyrius will be an important tool to incorporate pharmacogenomics in WGS-based precision medicine initiatives.
- Published
- 2021
- Full Text
- View/download PDF
49. PMAT: an efficient plant mitogenome assembly toolkit using low-coverage HiFi sequencing data
- Author
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Bi, Changwei, Shen, Fei, Han, Fuchuan, Qu, Yanshu, Hou, Jing, Xu, Kewang, Xu, Li-an, He, Wenchuang, Wu, Zhiqiang, and Yin, Tongming
- Abstract
Complete mitochondrial genomes (mitogenomes) of plants are valuable resources for nucleocytoplasmic interactions, plant evolution, and plant cytoplasmic male sterile line breeding. However, the complete assembly of plant mitogenomes is challenging due to frequent recombination events and horizontal gene transfers. Previous studies have adopted Illumina, PacBio, and Nanopore sequencing data to assemble plant mitogenomes, but the poor assembly completeness, low sequencing accuracy, and high cost limit the sampling capacity. Here, we present an efficient assembly toolkit (PMAT) for de novoassembly of plant mitogenomes using low-coverage HiFi sequencing data. PMAT has been applied to the de novoassembly of 13 broadly representative plant mitogenomes, outperforming existing organelle genome assemblers in terms of assembly accuracy and completeness. By evaluating the assembly of plant mitogenomes from different sequencing data, it was confirmed that PMAT only requires 1× HiFi sequencing data to obtain a complete plant mitogenome. The source code for PMAT is available at https://github.com/bichangwei/PMAT. The developed PMAT toolkit will indeed accelerate the understanding of evolutionary variation and breeding application of plant mitogenomes.
- Published
- 2024
- Full Text
- View/download PDF
50. Rational designed of PVDF membrane based on surface modification of εPL anchored by PC for crude oil emulsion separation
- Author
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Liu, Yan, Guo, Yunfei, Wang, Lilin, He, Jinsong, Luo, Ling, Tang, Weixu, Huang, Chengyi, Chen, Chao, Shen, Fei, and Zhang, Yanzong
- Abstract
For high-viscosity wastewater containing crude oil, the membrane material is easily clogged with contaminations, resulting in decreased flux and potentially loss of separation ability. In this study, a superhydrophilic/underwater superoleophobic PVDF membrane (PVDF-PC-εPL) was designed by the self-polymerization of proanthocyanidins (PC) and the grafting reaction of ε-polylysine (εPL), which showed a rough micro-nano structure without adding the inorganic particles. The PVDF-PC-εPL membrane displayed outstanding self-cleaning ability for high-viscosity crude oil, and the separation efficiency of the crude oil-in-water emulsion could be greater than 99.4%. The underwater oil contact angle (UWOCA) of the PVDF-PC-εPL membrane was 165°, after the PVDF-PC-εPL membrane had been exposed to air or water for 6 weeks, or soaked in different pH or seawater for 24 h, the UWOCA remained above 154° and the water contact angle was always 0°. The modification method on the PVDF membrane proposed in this study offers a fresh perspective and choice for preparing the oil-water separation materials.
- Published
- 2024
- Full Text
- View/download PDF
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