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1. Use of Surface Plasmon Resonance for Real-Time Measurements of the Global Conformational Transition in Human Phenylalanine Hydroxylase in Response to Substrate Binding and Catalytic Activation

Author

Flatmark, Torgeir, Stokka, Anne Jorunn, and Berge, Sissel V.

Abstract

In the present study the optical biosensor technique, based on the surface plasmon resonance (SPR) phenomenon, was used for real-time measurements of the reversible binding of the pterin cofactor (6R)-

Published
2001
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