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In this article, numerical simulation is performed for mixed convection lid-driven flow of CuO -water nanofluid enclosed in a curved corrugated. Cylindrical obstacles having three different constraints: (adiabatic, cold, and heated) at its surface are considered. Internal heat generation/absorption and uniform heat is provided at the vertical wall of the cavity. The bottom wall is insulated, and the curve surfaces are maintained with cold temperature. Mathematically equations are developed from physical problems and solved through Galerkin weighted residual method of FEM formulation. The effect of various Reynold number (Re), Darcy number (Da), solid volume fraction of nanoparticles (ϕ), heat generation/absorption coefficient (Q) and various cylindrical obstacle on velocity, Nusselt number, molecular movements and the flow structure has been studied. Nusselt number increases for high Darcy number due to the convection in lid cavity. For high Reynold number generally Nusselt numbers decrease or remain the same at the wall with an increase of nanoparticles in porous medium. There significant effect of heat sink coefficient on temperature profile and Nusselt number decreases with increasing of Q. [ABSTRACT FROM AUTHOR]