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Patients with a right dominant coronary artery anatomy account for a significant proportion of acute myocardial infarction cases, and this condition is associated with a better prognosis. However, there are limited data on the impact of coronary dominance on patients with acute total/subtotal occlusion of unprotected left main coronary artery (ULMCA). This study aimed to assess the impact of right coronary artery (RCA) dominance on long-term mortality in patients with acute total/subtotal occlusion of the ULMCA. From a multicenter registry, 132 cases of consecutive patients who had undergone emergent percutaneous coronary intervention (PCI) due to acute total/subtotal occlusion of the ULMCA were reviewed. Patients were classified into two groups according to the size of their RCA (dominant RCA group, n = 29; non-dominant RCA group, n = 103). Long-term outcomes were examined according to the presence of dominant RCA. Cardiopulmonary arrest (CPA) occurred in 52.3 % of patients before revascularization. All-cause death was significantly lower in the dominant RCA group than in the non-dominant RCA group. In the Cox regression model, dominant RCA was an independent predictor of all-cause death, as well as total occlusion of ULMCA, collateral from RCA, chronic kidney disease, and CPA. Patients were further analyzed according to the degree of stenosis of the ULMCA; patients with non-dominant RCA and total occlusive ULMCA had the worst outcome compared with the other groups. A dominant RCA might improve long-term mortality in patients with acute total/subtotal occlusion of the ULMCA who were treated with PCI. [Display omitted] • A dominant right coronary artery (RCA) is associated with a better prognosis in acute myocardial infarction. • A small RCA is associated with increased mortality in unprotected left main coronary artery (ULMCA)-acute occlusion. • Data on coronary dominance effects in acute occlusion of the ULMCA are limited. • A dominant RCA decreases the long-term mortality risk in percutaneous coronary intervention-treated ULMCA occlusion. [ABSTRACT FROM AUTHOR]

• Early intervention for non-ST elevation acute coronary syndrome (NSTE-ACS) with congestive heart failure (CHF) significantly prevented adverse cardiac events. • The benefit of early intervention was mainly observed in patients needing ventilators. • The risk of bleeding and acute kidney injury were higher in the early invasive group. • Most NSTE-ACS patients with CHF revealed advanced coronary artery disease. Although there are guidelines that recommend an early invasive strategy in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) and concomitant congestive heart failure (CHF), optimal timing of the invasive strategy remains controversial. Among 2045 patients who were admitted owing to NSTE-ACS or CHF, 300 presented with NSTE-ACS and concomitant CHF. Of the 300 patients, we enrolled 160 patients for whom coronary angiography (CAG) during their hospital stay was planned at the time of admission; 64 of these patients were classified into the early invasive group (<24 h) and 96 were classified to the delayed invasive group (≥24 h). We evaluated the primary outcome which was defined as a composite of cardiac mortality, life-threatening arrhythmia, and non-fatal myocardial infarction (MI). The median time between presentation and CAG was 2 h in the early invasive group and 240 h in the delayed group. During follow-up, the primary outcome was significantly lower in the early invasive group [hazard ratio (HR), 0.52; 95% confidence interval (CI), 0.30–0.87; p = 0.01]. After the adjustment of confounding factors, the primary outcome was significantly less frequent (HR, 0.44; 95% CI, 0.23–0.78; p = 0.004) in the early invasive group compared to the delayed invasive group. The early invasive strategy was associated with a lower risk of the composite primary outcome in the long-term follow-up of patients with NSTE-ACS and concomitant CHF. [ABSTRACT FROM AUTHOR]

• Distribution of bleeding risk scores was very high in patients who need oral anticoagulants after percutaneous coronary intervention. • The incidence of Thrombolysis in Myocardial Infarction significant bleeding was 29.8% during the 3-years follow-up. • That of Bleeding Academic Research Consortium (BARC) class ≥3 bleeding was 17.5% during the 3 years. • HAS-BLED and PRECISE-DAPT were better to stratify bleeding risk than Paris score. • All four scores could stratify BARC class ≥3 bleeding. No standardized tool exists for weighting bleeding risk before selecting an antithrombotic regimen in patients undergoing percutaneous coronary intervention (PCI) who require both oral anticoagulant (OAC) and antiplatelet agents. We performed PCI in 3718 consecutive patients between April 2011 and March 2017, 302 of whom were treated with both OAC and antiplatelet agents. We retrospectively evaluated the predictive performance of four major bleeding risk scores (HAS-BLED, ORBIT, PRECISE-DAPT, and PARIS score). Patients were followed for up to 3 years for bleeding events, defined as a composite of major and minor bleeding according to the Thrombolysis in Myocardial Infarction (TIMI) criteria and the Bleeding Academic Research Consortium (BARC) criteria. TIMI significant bleedings (major, minor, and requiring medical attention) were seen in 90 patients (29.8%); whereas the BARC class ≥3 bleedings were seen in 53 patients (17.5%). Regarding TIMI significant bleedings, HAS-BLED, ORBIT, and PRECISE-DAPT scores equally categorized high-risk patients, but the PARIS score could not [high-risk versus non-high-risk: hazard ratio (HR), 1.74; 95% confidence interval (CI), 1.15–2.64; p = 0.01; HR, 1.63; 95% CI, 1.08–2.48; p = 0.02; HR, 1.62; 95% CI, 1.06–2.51; p = 0.03; HR, 1.05; 95% CI, 0.70–1.63; p = 0.79, respectively); regarding BARC class ≥3 bleeding, all four scores could stratify high-risk patients (high-risk versus non-high-risk: HR, 2.23; 95% CI, 1.30–3.88; p = 0.004; HR, 2.25; 95% CI, 1.31–3.96; p = 0.003; HR, 3.87; 95% CI, 2.06–7.91; p < 0.0001; HR, 1.85; 95% CI, 1.04–3.47; p = 0.04, respectively). In patients taking an OAC undergoing PCI, HAS-BLED, ORBIT, and PRECISE-DAPT scores predicted TIMI significant bleeding events better than the PARIS score; whereas all four scores could predict BARC class ≥3 bleeding events. [ABSTRACT FROM AUTHOR]

Purpose: To evaluate the effect of a resin coating technique on dentin tensile bond strengths of dual-cured resin cements. Methods: 10 bovine dentin specimens were tested for tensile bond strengths of each of the following four materials: Panavia F, Link Max, Bistite II, Rely-X. Bovine dentin ground with 600-grit SiC was bonded with a resin cement according to the manufacturers' instructions or the resin coating technique, which was used in combination with one coat of a dentin adhesive; Clearfil SE Bond, Unifil Bond, One-Up Bond F or Single Bond, with one coat of a low viscosity micro-filled resin, Protect Liner-F. Each dentin adhesive and the low viscosity micro-filled resin were cured for 10 seconds and 20 seconds respectively. After 1 day storage in water, the specimens were subjected to the tensile bond test at a crosshead speed of 2 mm/minute. The data were analyzed by two-way ANOVA and Fisher's PLSD test (P< 0.05). The mode of failure after the tensile bond test was classified by visual inspection. The resin cement - dentin interfaces were examined by SEM. Results: The tensile bond strengths (MPa ± SD) of four resin cements to dentin with/without resin coating were: Panavia F (22.9 ± 3.1; 10.2 ± 2.5), Link Max (16.1 ± 4.4; 9.6 ± 3.2), Bistite II (14.8 ± 3.2; 14.3 ± 3.9), and Rely-X (15.7 ± 4.7; 13.5 ± 4.5), respectively. The resin coating significantly improved the bond strengths of resin cements to dentin in Panavia F and Link Max, while there were no significant differences of mean bond strengths between Bistite II or Rely-X with and without resin coating (P> 0.05). Regarding the fracture modes, complete and partial adhesive failures were observed in the cases without resin coating. For the resin coating groups, the fracture modes were much more complicated, although, adhesive failures rarely occurred. Hybrid layer formation was observed for all materials used. [ABSTRACT FROM AUTHOR]

Examines an efficient energy transfer in a donor-acceptor system with structural similarity and electronic complimentarity. Importance of energy transfer in a natural photosynthetic system; Similarity in structure of triphenylene and hexaazatriphenylene; Use of coupling reactions in preparing triphenylene derivatives.