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The characteristics of heat transfer in turbulent flow of Al2O3 nanofluid flowing in a 180-degree U-bend of triangular cross-section has been studied numerically employing finite volume method of ANSYS Fluent 16. Iterative solutions of the governing differential equations were carried out using appropriate boundary conditions. SST (Shear Stress Transport) k [?] o turbulence model has been utilized to solve the turbulent quantities. The duct Reynolds Number is varied in the range of 5000 to 30,000 and the volume fraction of nanofluid is varied from 0% to 5%. Constant temperature has been applied to the walls in different combinations in order to decide the maximum heat transfer with a particular case. It has been observed that there is a significant increase in heat transfer with both Reynolds number of flow and volume fraction of the nanofluid.