67 results on '"Wang, Fuqiang"'
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2. Enzymatic self-assembly/disassembly turns “ON”/“OFF” the mimetic hydrolytic activity of histidine nanofibers
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Sun, Xianbao, Wang, Manli, Liu, Xiaoyang, Zhan, Wenjun, Xu, Guangqiong, Jiang, Qiaochu, Xu, Hai-Dong, Wang, Fuqiang, and Liang, Gaolin
- Abstract
Mimetic enzymes are devised as alternates or supplements of natural enzymes in broad fields but regulating their activities in a switchable manner remains challenging. Herein, we proposed an enzymatic self-assembly/disassembly strategy to address this issue. A peptide molecule NapFFEYIH (YH) was rationally designed which, after self-assembling into nanofibers, lined up the histidine moieties to form active hydrolysis centers for mimicking hydrolase activity. Enzymatic dephosphorylation of NapF-FEYpIH (YpH) by alkaline phosphatase to yield YHalso turned “ON” the hydrolase activity. In turn, phosphorylation of YHby phosphokinase epidermal growth factor receptor to yield YpHdisassembled the nanofibers and thus turned the activity “OFF”. As such, the “ON”/“OFF” of the mimetic hydrolase activities could be regulated under physiological conditions through ALP/EGFR-mediated self-assembly/disassembly of histidine nanofibers. This work provides a feasible strategy for the on-demand fabrication of artificial enzymes with controllable and superior activities.
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- 2024
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3. Performance of the Multilayer Film for Infrared Stealth based on VO2Thermochromism
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Li, Yaru, Wang, Fuqiang, Zhang, Aoyu, Fu, Zhichang, Su, Ronghua, Gao, Tengfei, Wang, Zhen, and Guo, Jicheng
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With the development of detection and identification technology, infrared stealth is of great value to realize anti-reconnaissance detection of military targets. At present, infrared stealth materials generally have deficiency, such as complex structure, inconvenient radiation regulation and cumbersome preparation steps, which greatly limit the practical application of infrared stealth materials. In view of the above deficiency of infrared stealth materials, we proposed a kind of multilayer film for infrared stealth using VO2thermochromism based on the temperature response mechanism of tuna to adjust its color, and through the intelligent reversible radiation regulation mechanism to meet the infrared stealth requirements of tanks in different actual scenes. The results show that when the temperature increases from 300 K to 373 K, the peak emissivity of the film decreases from 94% to 20% in the 8–14 µm band after structural optimization, which can realize the infrared stealth of the high temperature target in the 8–14 µm band. The average emissivity of the multilayer film for infrared stealth at 3–5 µm and 8–14 µm band can be reduced to 34% and 27% at 373 K, and the peak emissivity at 5–8 µm band can reach 65%, realizing dual-band infrared stealth in the 3–5 µm and 8–14 µm bands and heat dissipation in the 5–8 µm band. The multilayer film for infrared stealth based on VO2thermochromism designed by the authors can meet the characteristics of simple film structure, convenient radiation regulation and simple preparation.
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- 2024
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4. Tunnel Assembly-Type Temporary Support Joint Bearing Capacity
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Cheng, Xuansheng, Wang, Hao, Bu, Yuyue, Liu, Gongning, and Wang, Fuqiang
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For the tunnel construction, the RC central diaphragms take a long time to close and is not easy to reuse. These problems can be solved effectively if temporary steel structure supports are used instead of traditional concrete partition supports. Based on Xicheng Mountain tunnel project, this paper analyzes the ultimate bearing capacity of four types of steel structures by numerical simulation. The results show that it is feasible to apply prefabricated temporary steel support structure to tunnel construction. Prefabricated temporary steel support structure is fast installation and easy to reuse; the ultimate bearing capacity of the joint with diagonal braces is 40% higher than that of the joint without diagonal braces.
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- 2024
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5. Multiple Nanoparticles Coupling Strategy for Enhancing Optical Filter Performance of Spectral Splitter Used in Photovoltaic/Thermal System
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Liang, Huaxu, Huang, Xin, Wang, Fuqiang, Cheng, Ziming, and Dong, Yan
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Selective absorptive nanofluid can pre-absorb certain sunlight wavelength that cannot be used by PV and transmits remaining sunlight to the surface of PV, which can decouple PV from the thermal receiver spatially. In order to improve the harvesting of electricity and high-temperature thermal nanofluid, it is important to design an optimal optical filter window (transmit sunlight with wavelengths of 732–1067 nm to the surface of the photovoltaic cell and absorb the remaining sunlight). However, designing optimal optical filter is facing following challenges: (1) inherently narrow selective absorptivity property of single nanoparticle; (2) simplified numerical calculation method calculating transmittance; (3) ignoring the shape of the nanoparticle. In this study, the idea of using multiple nanoparticles coupling effect to design an optical filter is proposed, which can superimpose the narrow absorption bandwidth of different nanoparticles to obtain a wide absorption bandwidth of the whole system. In addition, an improved transmission method considering light-matter interaction at air/vessel and liquid/vessel interfaces is adopted to compute the transmittance. The results calculated by improved transmission method are more accurate than widely used traditional Lambert-Beer law, which is verified by experimental test. Furthermore, the effect of nanoparticle shape on spectral transmittance is also investigated, which shows that spiny Ag can approximately extend absorbance from 400 nm to 600 nm compared to nanosphere silver. Finally, the results show that optical filter efficiency of nanofluids with multiple nanoparticles coupling (Ag, spiny Ag, ZnO, ITO) can reached up to 35%.
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- 2024
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6. "Warm in Winter and Cool in Summer": Scalable Biochameleon Inspired Temperature-Adaptive Coating with Easy Preparation and Construction.
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Dong, Yan, Meng, Weifeng, Wang, Fuqiang, Han, Han, Liang, Huaxu, Li, Xiang, Zou, Yanan, Yang, Chun, Xu, Zenghui, Yan, Yuying, and Cheng, Ziming
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- 2023
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7. Application of CoFe2O4-NiO nanoparticle-coated foam-structured material in a high-flux solar thermochemical reactor
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Zhang, Hao, Zhang, XiaoMi, Yang, DaZhi, Shuai, Yong, Guene Lougou, Bachirou, Pan, QingHui, and Wang, FuQiang
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The splitting of carbon dioxide through the two-step solar thermochemical cycle presents enormous potential, for it holds the dual functionalities of solar fuel production and carbon-based energy recovery. However, the industrialization of this technology is impeded by two critical factors: The absence of fully developed oxygen carriers and advanced reaction devices that deliver exceptional performance. In order to identify a potentially effective oxygen carrier, 50 wt% NiO-modified CoFe2O4is selected as the active component and characterized by means of thermogravimetry, scanning electron microscopy, and energy dispersive spectroscopy, so as to clarify its oxygen exchange capacity, micromorphology and elemental composition in high-temperature thermochemical cycles. Further, nanoparticle-coated foam-structured materials are prepared in combination with SiC ceramic foam for experimental testing in a high-flux solar reactor. The results indicate that a peak CO yield of 1.96 mL min−1g−1can be gained in a 1500–1250 K preliminary test, demonstrating the application potential of the material. In contrast to conventional redox materials, the CO2activity of the materials synthesized in this study exhibits an enhancement with rising oxidation temperature. It means that isothermal cycles can potentially achieve higher conversion and fuel yield than non-isothermal cycles, while simultaneously reducing the amount of irreversible heat loss during high-temperature cycling. Although the estimated steady-state thermal efficiency of the solar reactor can reach up to 42%, further optimization of the reactor design is necessary to enhance energy conversion efficiency, as it is partially limited by the dimensions of the reaction chamber.
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- 2023
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8. “Warm in Winter and Cool in Summer”: Scalable Biochameleon Inspired Temperature-Adaptive Coating with Easy Preparation and Construction
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Dong, Yan, Meng, Weifeng, Wang, Fuqiang, Han, Han, Liang, Huaxu, Li, Xiang, Zou, Yanan, Yang, Chun, Xu, Zenghui, Yan, Yuying, and Cheng, Ziming
- Abstract
The highly reflective solar radiation of passive daytime radiative cooling (PDRC) increases heating energy consumption in the cold winter. Inspired by the temperature-adaptive skin color of chameleon, we efficiently combine temperature-adaptive solar absorption and PDRC technology to achieve “warm in winter and cool in summer”. The temperature-adaptive radiative cooling coating (TARCC) with color variability is designed and fabricated, achieving 41% visible light regulation capability. Comprehensive seasonal outdoor tests confirm the reliability of the TARCC: in summer, the TARCC exhibits high solar reflectance (∼93%) and atmospheric transmission window emittance (∼94%), resulting in a 6.5 K subambient temperature. In the winter, the TARCC’s dark color strongly absorbs solar radiation, resulting in a 4.3 K temperature rise. Compared with PDRC coatings, the TARCC can save up to 20% of annual energy in midlatitude regions and increase suitable human hours by 55%. With its low cost, easy preparation, and simple construction, the TARCC shows promise for achieving sustainable and comfortable indoor environments.
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- 2023
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9. Economic Analysis and Life Cycle Environmental Assessment of Imidazolium-Based Ionic Liquids for Separation of the Methanol/Dimethyl Carbonate Azeotrope.
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Guo, Chao, Liu, Xiaoyan, Wang, Fuqiang, Cao, Yuqing, Zheng, Size, and He, Ge
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- 2023
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10. Scalable Bio-Skin-Inspired Radiative Cooling Metafabric for Breaking Trade-Off between Optical Properties and Application Requirements.
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Zhang, Xinping, Cheng, Ziming, Yang, Dongling, Dong, Yan, Shi, Xuhang, Liang, Huaxu, Wang, Fuqiang, Han, Han, Meng, Weifeng, Shuai, Yong, and Yan, Yuying
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- 2023
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11. The deubiquitylating enzyme USP35 restricts regulated cell death to promote survival of renal clear cell carcinoma
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Wang, Shanshan, Wang, Taishu, Zhang, Xuehong, Cheng, Shaoxuan, Chen, Chaoqun, Yang, Guoheng, Wang, Fuqiang, Wang, Ruilin, Zhang, Qingqing, Yang, Dian, Zhang, Yingqiu, Liu, Shuyan, Qin, Hongqiang, Liu, Quentin, and Liu, Han
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The ubiquitin-proteasome system governs a wide spectrum of cellular events and offers therapeutic opportunities for pharmacological intervention in cancer treatment. Renal clear cell carcinoma represents the predominant histological subtype and accounts for the majority of cancer death related to kidney malignancies. Through a systematic survey in the association of human ubiquitin-specific proteases with patient prognosis of renal clear cell carcinoma and subsequent phenotypic validation, we uncovered the tumor-promoting role of USP35. Biochemical characterizations confirmed the stabilizing effects of USP35 towards multiple members of the IAP family in an enzymatic activity-dependent manner. USP35 silencing led to reduced expression levels of IAP proteins, which were accompanied with increased cellular apoptosis. Further transcriptomic analysis revealed that USP35 knockdown affected the expression levels of NRF2 downstream transcripts, which were conferred by compromised NRF2 abundance. USP35 functions to maintain NRF2 levels by catalyzing its deubiquitylation and thus antagonizing degradation. NRF2 reduction imposed by USP35 silencing rendered renal clear cell carcinoma cells increased sensitivity to ferroptosis induction. Finally, induced USP35 knockdown markedly attenuated xenograft formation of renal clear cell carcinoma in nude mice. Hence, our findings reveal a number of USP35 substrates and uncover the protecting roles of USP35 against both apoptosis and ferroptosis in renal clear cell carcinoma.
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- 2023
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12. Design of hierarchical nanohole for efficient broadband light absorption of MAPbI3perovskite material based solar cell with thin absorber layer
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Liang, Huaxu, Wen, Zhenlong, Wang, Fuqiang, and Cheng, Ziming
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Perovskite solar cell has the advantages of low dosage of toxic materials, flexibility and consumer-oriented, which has significant development potential. Nanophotonic structure shows superior performance to common geometrical structure in controlling light transfer, which can capture and trap light, and thus improving the light absorption while reducing its thickness. In this work, novel wavelength-sized hierarchical nanohole is devised toward maximum broadband light absorption. The hierarchical nanohole can excite quasi-guided modes to improve light absorption, the electric field distribution is shown and demonstrated. The proposed perovskite solar cells with hierarchical nanohole outperform a planar solar cell by 17% in JSCand outperform a perovskite solar cell with one nanohole reference by 6.7% in JSC. In addition, the effects of hierarchical nanohole geometry on performance of perovskite solar cell are investigated. Overall, this work provides a new design for the ultra-thin perovskite solar cell with high energy conversion efficiency.
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- 2023
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13. Safety and feasibility of a modularized procedure for trans-subxiphoid robotic extended thymectomy
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Zhang, Hanlu, Wang, Fuqiang, Qiu, Guanghao, Li, Zhiyang, Peng, Lei, Wang, Xuyang, Xie, Shenglong, Chen, Long-Qi, and Wang, Yun
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Background: The purpose of this study was to introduce an “eight-step modularized procedure (M-RET)” for trans-subxiphoid robotic extended thymectomy for patients with myasthenia gravis (MG). Its safety and feasibility were further verified in this study. Materials and methods: This retrospective study included 87 consecutive MG patients who underwent trans-subxiphoid robotic extended thymectomy at our institution between September 2016 and August 2021. According to different resection models, patients were divided into two groups: traditional trans-subxiphoid robotic extended thymectomy group (T-RET group) and eight-step modularized technique group (M-RET group). Baseline demographic characteristics and operation-related parameters were collected and compared between the two groups. Results: There were 41 (47.1%) patients in the M-RET group and 46 (52.9%) patients in the T-RET group. The M-RET group resected a greater amount of mediastinal adipose tissues and required more dissection time (median and interquartile range: 135.0, 125.0 to 164.0 v.120.0, 105.0 to 153.8, P= 0.006) compared with the T-RET group. There were no statistically significant differences in terms of the intraoperative blood loss, duration of chest drainage, length of hospital stay, and postoperative complications between the two groups. There was no mortality or conversion in each of the two groups and all patients recovered well upon discharge. Conclusion: The eight-step modularized technique of trans-subxiphoid robotic extended thymectomy was verified to be a safe, effective, radical procedure, which offers unique superiority over ectopic thymic tissue resection. Graphical abstract:
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- 2023
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14. Research on a robust sensor maneuvering target tracking algorithm
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Yue, Yang, Rashid, Tarik Ahmed, Xu, Gexing, Wang, Fuqiang, Zhao, Wei, and Zhang, Jianan
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- 2024
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15. Remote sensing based characterization of spatial and temporal variability of drought in MU Us Sandy and analysis of climatic factors
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Luo, Yinhe, Wang, Yi, Wang, Sinan, Wu, Yingjie, Wang, Fuqiang, Li, Ruiping, and Zhao, Qian
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- 2024
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16. A radiomics strategy based on CT intra-tumoral and peritumoral regions for preoperative prediction of neoadjuvant chemoradiotherapy for esophageal cancer.
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Li, Zhiyang, Wang, Fuqiang, Zhang, Hanlu, Xie, Shenglong, Peng, Lei, Xu, Hui, and Wang, Yun
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ESOPHAGEAL cancer ,RADIOMICS ,CHEMORADIOTHERAPY ,RECEIVER operating characteristic curves ,COMPUTED tomography - Abstract
Develop a method for selecting esophageal cancer patients achieving pathological complete response with pre-neoadjuvant therapy chest-enhanced CT scans. Two hundred and one patients from center 1 were enrolled, split into training and testing sets (7:3 ratio), with an external validation set of 30 patients from center 2. Radiomics features from intra-tumoral and peritumoral images were extracted and dimensionally reduced using Student's t-test and least absolute shrinkage and selection operator. Four machine learning classifiers were employed to build models, with the best-performing models selected based on accuracy and stability. ROC curves were utilized to determine the top prediction model, and its generalizability was evaluated on the external validation set. Among 16 models, the integrated-XGBoost and integrated-random forest models performed the best, with average ROC AUCs of 0.906 and 0.918, respectively, and RSDs of 6.26 and 6.89 in the training set. In the testing set, AUCs were 0.845 and 0.871, showing no significant difference in ROC curves. External validation set AUCs for integrated-XGBoost and integrated-random forest models were 0.650 and 0.749. Incorporating peritumoral radiomics features into the analysis enhances predictive performance for esophageal cancer patients undergoing neoadjuvant chemoradiotherapy, paving the way for improved treatment outcomes. [ABSTRACT FROM AUTHOR]
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- 2024
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17. Liquid Metal-Modified Nanoporous SiGe Alloy as an Anode for Li-Ion Batteries and Its Self-Healing Performance.
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Meng, Fanran, Wang, Fuqiang, Yu, Haohui, Zhao, Zijun, Lv, Yang, Ma, Chao, Zhang, Dong, and Liu, Xizheng
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- 2021
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18. Navigation Situation Assessment of Autonomous Surface Vehicles in a Cooperative Hunting Environment
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Zhang, Wenjun, Wang, Fuqiang, Gao, Qiqiang, and Qu, Xingru
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This paper proposes a navigation situation assessment method for autonomous surface vehicles (ASVs) in a cooperative hunting environment. By virtue of the repulsion function expressed in the artificial potential field, the navigation situation of hunting ASVs and target ASVs is firstly described. And the hunting situation is also constructed to describe the cooperative hunting. Based on the navigation situation and the hunting situation, a navigation situation assessment method for cooperative hunting of multiple ASVs is designed, where the number of hunting vehicles and the hunting radius can be successfully computed. Simulation results show that this proposed situation assessment method can give an optimised formation pattern and provide an effective reference for cooperative hunting of ASVs.
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- 2022
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19. Microstructure and Thermal Properties of Inert Plasma-Sprayed Tungsten Coating on SiC-Coated Carbon/Carbon Composites
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Wang, Fuqiang, Chen, Jian, Cui, Hong, Ji, Alin, Xie, Dong, and Zhang, Zhaofu
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AbstractThe coating technology of tungsten on carbon/carbon (C/C) composite is an important issue for fusion experimental device components. In this study, an interlayer of chemical vapor deposition SiC between tungsten coating and C/C substrate was used. A tungsten coating 320 μm thick was successfully deposited on SiC-coated C/C substrate by inert plasma spray. The microstructure, roughness, and constituents of W-SiC-C/C composite materials were investigated using a scanning electron microscope, energy dispersive X-ray spectroscope, X-ray diffractometer, and atomic force microscope. The tungsten coating structure that may prevent crack propagation essentially consisted of a stacked lamellar columnar microstructure and particle cluster microstructures. The interfaces between the tungsten and SiC coating and between the SiC coating and the C/C were clear. The SiC interlayer acts as a barrier for carbon and tungsten diffusion. The thermal conductivity of the system was calculated by the mixture rule, which was 47.33 to 82.35 W/(m·K). The thermal expansion coefficient of W-SiC-C/C was negative at room temperature and up to 1.5 × 10−6/K for elevated temperature.
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- 2022
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20. Surgical Tips to Improve Completeness of Transsubxiphoid Robotic Extended Thymectomy.
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Zhang, Hanlu, Wang, Fuqiang, Qiu, Guanghao, Li, Zhiyang, Chen, Long-Qi, and Wang, Yun
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- 2022
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21. A framework based on generational and environmental response strategies for dynamic multi-objective optimization.
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Li, Qingya, Liu, Xiangzhi, Wang, Fuqiang, Wang, Shuai, Zhang, Peng, and Wu, Xiaoming
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Due to the dynamics and uncertainty of the dynamic multi-objective optimization problems (DMOPs), it is difficult for algorithms to find a satisfactory solution set before the next environmental change, especially for some complex environments. One reason may be that the information in the environmental static stage cannot be used well in the traditional framework. In this paper, a novel framework based on generational and environmental response strategies (FGERS) is proposed, in which response strategies are run both in the environmental change stage and the environmental static stage to obtain population evolution information of those both stages. Unlike in the traditional framework, response strategies are only run in the environmental change stage. For simplicity, the feed-forward center point strategy was chosen to be the response strategy in the novel dynamic framework (FGERS-CPS). FGERS-CPS is not only to predict change trend of the optimum solution set in the environmental change stage, but to predict the evolution trend of the population after several generations in the environmental static stage. Together with the feed-forward center point strategy, a simple memory strategy and adaptive diversity maintenance strategy were used to form the complete FGERS-CPS. On 13 DMOPs with various characteristics, FGERS-CPS was compared with four classical response strategies in the traditional framework. Experimental results show that FGERS-CPS is effective for DMOPs. • The novel framework includes the generational response strategy. • The feed-forward center point strategy was an example run in the novel framework. • The statistical results showed that the proposed strategy is very competitive. • The experiments denoted the novel framework is better. [ABSTRACT FROM AUTHOR]
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- 2024
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22. PTEN-mediated FOXO signaling affects autophagy, migration and invasion of rheumatoid arthritis fibroblast-like synoviocytes.
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Chen, Bojie, Wang, Fuqiang, Zhang, Yun, and Liu, Fang
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RHEUMATOID arthritis ,AUTOPHAGY ,CELL migration ,GENETIC overexpression ,AUTOIMMUNE diseases - Abstract
Rheumatoid arthritis (RA) is a chronic, progressive, systemic autoimmune disease. Among them, abnormal proliferation, migration and vascularization of fibroblast-like synoviocytes (FLS) are the main pathological basis of persistent synovitis and bone destruction in RA. In the current study, we attempted to find effective molecular mechanisms for the treatment of RA by investigating RA-FLS. Firstly, the study was conducted to identify the potential target gene PTEN and its related signaling pathway through bioinformatics analysis. Subsequently, the target gene PTEN overexpression was regulated by cell transfection. The expression of FOXO signaling factors and autophagy-related proteins were detected by western blotting assay. Cell proliferation was measured by CCK-8 and EdU assays. Inflammation level was detected by ELISA. Cell migration and invasion were detected using wound healing assay and transwell chamber assay, respectively. Cell apoptosis was detected using flow cytometry. The results showed that overexpression of PTEN activated FOXO1 signaling in RA-FLS, and regulated autophagy, proliferation, invasion, migration, and the levels of pro-inflammatory factors in the disease. In conclusion, PTEN might provide an effective therapeutic strategy for rheumatoid arthritis by mediating the FOXO1 signaling pathway. • PTEN-mediated FOXO1 signaling regulates autophagy in rheumatoid arthritis. • Overexpression PTEN affects cell proliferation, invasion and migration in fibroblast-like synoviocytes. • Overexpression PTEN affects inflammation and apoptosis in fibroblast-like synoviocytes. [ABSTRACT FROM AUTHOR]
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- 2024
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23. Thermal Performance Analysis of PCM Capsules Packed-Bed System with Biomimetic Leaf Hierarchical Porous Structure
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Dong, Yan, Wang, Fuqiang, Yang, Luwei, Shi, Xuhang, Zhang, Guoliang, and Shuai, Yong
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As an efficient natural selection nutrient transport system, biomimetic leaf hierarchical porous structure has unique advantages in material transportation and energy transfer. Biomimetic leaf hierarchical porous structure has been widely used in solar thermochemical reactions, photocatalysis, and energy storage. To improve the thermal efficiency and reduce the power consumption, the authors introduce the idea of bionic leaf hierarchical porous structure packed-bed latent heat thermal energy storage (LHTES) system. Under the same porosity, the diameter of the PCM capsules is designed to change along the flow direction to optimize the thermal performance. The effects of velocity on temperature distribution, pressure drop, liquid fraction, and thermal storage capacity of the conventional uniform model and bionic leaf hierarchical porous model are analyzed. The results show that the bionic leaf hierarchical porous structure can thin the thickness of the thermocline, reduce the pressure drop, increase the heat transfer area, and improve the thermal response of the packed-bed compared with the conventional uniform model. The maximum increases of liquid fraction and completion rate are 36.6% and 20.3% with pressure drop reduction of 25 Pa, respectively. The maximum decrease of the above-melting point (MP) thermocline is 51.7% as well. These results provide suggestions to optimize the packed-bed LHTES system and improve its thermal performance under practical conditions.
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- 2021
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24. Numerical study on the thermal performance of packed-bed latent heat thermal energy storage system with biomimetic alveoli structure capsule
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Wang, FuQiang, Dong, Yan, Li, Yang, Xu, Jie, and Zhang, GuoLiang
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Bionics provides a positive and beneficial impact on the development of various materials and systems, which has been widely used in energy storage, heat transfer enhancement, and solar thermochemical reactions. In this paper, the idea of heat storage unit with biomimetic alveoli structure is proposed and introduced to increase the heat transfer area and improve the thermal performance of the packed-bed latent heat thermal energy storage (LHTES) system. The effects of heat storage unit structure on temperature distribution, liquid fraction, thermal storage capacity, and other performance indexes of the conventional model and biomimetic model are analyzed. The numerical results indicate that the biomimetic alveoli structure can improve the thermal response of heat storage unit, increase the specific surface area, and achieve a faster heat storage process of the packed-bed compared with the conventional structure. Among various existing models, the double-cell model has a significant improvement. Compared with the conventional model, the maximum increase of liquid fraction and charging efficiency are 9.8% and 6.4%, respectively. This study can provide references to optimize packed-bed LHTES and improve its thermal performance under practical conditions.
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- 2021
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25. Effects of ordered hierarchically porous structure on methane reforming performance in solar foam reactor.
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Shi, Xuhang, Shuai, Yong, Wang, Fuqiang, Zhang, Chuanxin, Cheng, Ziming, and Chen, Xue
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PORE size distribution ,FINITE volume method ,METHANE - Abstract
• Methane reforming in solar foam reactor with hierarchically porous structure is studied. • Hierarchically porous structure can increase the methane conversion. • Pore diameter combination with optimum methane conversion at d 1 = 1.0 mm and d 2 = 2.5 mm. • Maximum conversion is obtained when the length of the small holes is 0.02 m. Hierarchically porous structures are a new type of biomimetic structures that have important applications in several fields. In this study, we aimed to put forward and introduce a new type ordered hierarchical porous structure in the design of solar thermal chemical reaction chambers to utilize CH 4 and CO 2. The model of the chambers was established based on the hierarchically porous structure. The effect of hierarchically porous structures on the methane reforming performance of a solar thermal chemical reaction chamber was studied. Based on the finite volume method, FLUENT software was combined with user-defined functions to calculate the effect of different pore size combinations and distributions on the methane conversion. The hierarchically porous structure was found to increase the methane conversion because of the excellent flow characteristics and radiation properties of the structure. The different pore size combinations of the hierarchically porous structure were analyzed, and the optimal pore size combination that results in the maximum methane conversion was obtained. Similarly, the different pore size distributions of the hierarchically porous structure were analyzed, and the optimal pore size distribution was obtained. The conversion of methane is the highest when the length of the small hole section is 0.02 m. This study can provide a new process and reference for the utilization of CH 4 and CO 2 and design of solar high-temperature thermochemical reaction chambers, based on the hierarchically porous structure. The maximum methane conversion of approximately 85% was found at d 1 = 1.0 mm, d 2 = 2.5 mm, and L 1 = 0.02 m. [ABSTRACT FROM AUTHOR]
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- 2020
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26. Quantitative Proteomics Combined with Two Genetic Strategies for Screening Substrates of Ubiquitin Ligase Hrt3.
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Lan, Qiuyan, Wang, Yihao, Sun, Zhen, Li, Yanchang, Zhang, Cheng, Chang, Lei, Gao, Yue, Wu, Junzhu, Wang, Fuqiang, and Xu, Ping
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- 2020
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27. Ac-LysargiNase Complements Trypsin for the Identification of Ubiquitinated Sites.
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Xiao, Weidi, Zhang, Junling, Wang, Yihao, Liu, Zijuan, Wang, Fuqiang, Sun, Jinshuai, Chang, Lei, Xia, Zongping, Li, Yanchang, and Xu, Ping
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- 2019
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28. Unambiguous Phosphosite Localization through the Combination of Trypsin and LysargiNase Mirror Spectra in a Large-Scale Phosphoproteome Study
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Xu, Feng, Yu, Li, Peng, Xuehui, Zhang, Junling, Li, Suzhen, Liu, Shu, Yin, Yanan, An, Zhiwu, Wang, Fuqiang, Fu, Yan, and Xu, Ping
- Abstract
Understanding of the kinase-guided signaling pathways requires the identification and analysis of phosphosites. Mass spectrometry (MS)-based phosphoproteomics is a rapid and highly sensitive approach for high-throughput identification of phosphosites. However, phosphosite determination from MS data with a single protease is more likely to be ambiguous, regardless of the strategy used for phosphopeptide detection. Here, we explored the application of LysargiNase, which was recently reported to mirror trypsin in specificity to cleave arginine and lysine residues exclusively at the N-terminal side. We found that the combination of trypsin and LysargiNase mirror spectra resulted in higher ion coverage in MS2spectra. The median ion coverage values of b ions in tryptic spectra, LysargiNase spectra, and combined spectra are 8.3, 20.5, and 25.0%, respectively. As for the median ion coverage of y ions, these values are 27.8, 10.0, and 32.3%. Higher ion coverage was helpful to pinpoint the precise phosphosites. Compared to trypsin alone, the combined use of trypsin and LysargiNase mirror spectra enabled 67.1% of mirror spectra with unreliable scores (confidence score <0.75) to become reliable (confidence score ≥ 0.75). Meanwhile, all of the mirror peptide-spectrum matches (PSMs) with multiple potential phosphosites from trypsin and LysargiNase digests could be assigned one precise phosphosite after applying the combination strategy. Besides, the combination strategy could identify more novel phosphosites than the union strategy did. We synthesized three phosphopeptides corresponding to the three novel phosphosites and validated the reliability of the identification. Taken together, our data demonstrated the distinctive potential of the combination strategy presented here for unambiguous phosphosite localization (Project accession PXD011178).
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- 2020
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29. Water permeability in MXene membranes: Process matters
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Zhou, Hang, Wang, Yuwei, Wang, Fuqiang, Deng, Hao, Song, Yongchen, Li, Changping, and Ling, Zheng
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The voids from less ordered stack rather than in-plane defects and interlayer galleries were confirmed to contribute to the large water permeability of membranes assembled from delaminated MXene nanoflakes. The voids can be controlled viadeposit rate of MXene nanoflakes.
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- 2020
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30. Effects of ordered hierarchically porous structure on methane reforming performance in solar foam reactor
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Shi, Xuhang, Shuai, Yong, Wang, Fuqiang, Zhang, Chuanxin, Cheng, Ziming, and Chen, Xue
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- 2020
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31. Quantitative Proteomics Combined with Two Genetic Strategies for Screening Substrates of Ubiquitin Ligase Hrt3
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Lan, Qiuyan, Wang, Yihao, Sun, Zhen, Li, Yanchang, Zhang, Cheng, Chang, Lei, Gao, Yue, Wu, Junzhu, Wang, Fuqiang, and Xu, Ping
- Abstract
Ubiquitin ligases (E3s) serve as key regulators for the ubiquitylation-mediated pathway. The identification of the corresponding relationship between E3 and its substrates is challenging but required for understanding the regulatory network of ubiquitylation. The low abundance of ubiquitinated conjugates and high redundancy of E3 substrate regulation made the screening pretty hard. Herein, we combined SILAC-based quantitative proteomics with two contrary genetic methods (overexpression and knockout) in theory for E3 (Hrt3, the F-box subunit of the SCF complex) substrate screening. The knockout method could not overcome the constraint mentioned above, while the overexpression approach turned on the access to the potential substrates of E3. Subsequently, we obtained 77 candidates, which are involved in many critical biological processes and need to be verified in the future. Within these candidates, we confirmed the relationship between one of the candidates Nce103 and Hrt3 and linked Hrt3 with oxygen sensitivity and oxidative stress response in which Nce103 took part as well. This research is also beneficial for understanding the impact of oxygen supply on regulation of yeast growth through the ubiquitination of Nce103.
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- 2020
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32. Ac-LysargiNase Complements Trypsin for the Identification of Ubiquitinated Sites
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Xiao, Weidi, Zhang, Junling, Wang, Yihao, Liu, Zijuan, Wang, Fuqiang, Sun, Jinshuai, Chang, Lei, Xia, Zongping, Li, Yanchang, and Xu, Ping
- Abstract
Mass spectrometry (MS)-based identification of ubiquitinated sites requires trypsin digestion prior to MS analysis, and a signature peptide was produced with a diglycine residue attached to the ubiquitinated lysine (K-ε-GG peptide). However, the missed cleavage of modified lysines by trypsin results in modified peptides with increased length and charge, whose detection by MS analysis is suppressed by the vast majority of internally unmodified peptides. LysargiNase, the mirrored trypsin, is reported to cleave before lysine and arginine residues and to be favorable for the identification of methylation and phosphorylation, but its digestive characteristics related to ubiquitination are unclear. Herein, we tested the capacity of the in-house developed acetylated LysargiNase (Ac-LysargiNase) with high activity and stability, for cleaving ubiquitinated sites in both the seven types of ubiquitin chains and their corresponding K-ε-GG peptides. Interestingly, Ac-LysargiNase could efficiently cleave the K63-linked chain but had little effect on the other types of chains. Additionally, Ac-LysargiNase had higher exopeptidase activity than trypsin. Utilizing these features of the paired mirror proteases, a workflow of trypsin and Ac-LysargiNase tandem digestion was developed for the identification of ubiquitinated proteins. Through this method, the charge states and ionization capacity of the unmodified peptides were efficiently reduced, and the identification of modified sites was consequently increased by 30% to 50%. Strikingly, approximately 15% of the modified sites were cleaved by Ac-LysargiNase, resulting in shorter K-ε-GG peptides for better identification. The enzyme Ac-LysargiNase is expected to serve as an option for increasing the efficiency of modified site identification in ubiquitome research.
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- 2019
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33. Elevated N‐methyltransferase expression induced by hepatic stellate cells contributes to the metastasis of hepatocellular carcinoma via regulation of the CD44v3 isoform.
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Li, Jie, You, Song, Zhang, Sheng, Hu, Qing, Wang, Fuqiang, Chi, Xiaoqin, Zhao, Wenxiu, Xie, Chengrong, Zhang, Changmao, Yu, Yaqi, Liu, Jianmin, Zhao, Yue, Liu, Pingguo, Zhang, Yi, Wei, Xujin, Li, Qiu, Wang, Xiaomin, and Yin, Zhenyu
- Abstract
The cross‐talk between hepatic stellate cells (HSCs) and hepatic carcinoma cells contributes to hepatocellular carcinoma (HCC) progression, but the underlying mechanism is largely unknown. We report here that activated HSCs induce upregulation of nicotinamide N‐methyltransferase (NNMT), which is known to regulate multiple metabolic pathways in hepatoma cells of the liver. High levels of NNMT in HCC tissues were positively correlated with vascular invasion, increased serum HBV‐DNA levels, and distant metastasis. In addition, functional assays showed that NNMT promoted HCC cell invasion and metastasis by altering the histone H3 methylation on 27 methylation pattern and transcriptionally activating cluster of differentiation 44 (CD44). NNMT‐mediated N6‐methyladenosine modification of CD44 mRNA resulted in the formation of a CD44v3 splice variant, while its product 1‐methyl‐nicotinamide stabilized CD44 protein by preventing ubiquitin‐mediated degradation. Finally, NNMT was also shown to be a target of statins that inhibited metastasis of hepatoma cells. Taken together, our study shows for the first time that the NNMT/CD44v3 axis regulates HCC metastasis and presents NNMT as a promising prognostic biomarker and therapeutic target for HCC. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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34. Investigation on Optical Properties and Solar Energy Conversion Efficiency of Spectral Splitting PV/T system.
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Liang, HuaXu, Cheng, ZiMing, Wang, Hao, Tan, Jianyu, and Wang, Fuqiang
- Abstract
Abstract This paper taken SiO 2 nanofluid spectral splitting PV/T system on as the object of the research, considering the effects of scattering, the Mie scattering theory combined with Monte Carlo Ray Tracing (Tracepro software) method was developed to study optical properties and solar energy conversion efficiency with SiO 2 nanofluid volume fraction and particle diameter. It is found that with the diameter of the nanoparticle is 5 nm, the spectral transmittance does not change with the increasing volume fraction, and the scattering effect of the nanofluid can be neglected, while the diameter of the nanoparticle is larger than 15 nm, the spectral transmittance change greatly, and the scattering needs to be considered; with the volume fraction and the diameter of SiO 2 nanofluids becoming larger, the total energy absorbed by the photothermal conversion of nanofluid increase slightly, so the scattering of SiO 2 nanofluid have minor effect on photothermal conversion of PV/T system, while the photoelectric conversion efficiency reduce because of the increasing scattering coefficient, which made total solar energy conversion efficiency reduced. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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35. Human ear inspired solar thermochemical reactor for steam methane reforming with the consideration of minimum Gibbs free energy principle
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Song, Jintao, Cheng, Ziming, Fan, Yaping, Wang, Fuqiang, Shi, Xuhang, Xu, Jie, and Yi, Hongliang
- Abstract
The non-uniformity temperature field of direct solar thermochemical reactors severely decreases the energy conversion efficiency of solar-to-fuel. Inspired by the physical mechanism by which the human ear can collect more sound waves, associating the similarity between sound waves and electromagnetic waves in the fluctuation equation as well as the propagation law, with the considering of the minimum Gibbs free energy principle, a biomimetic human ear solar thermochemical reactor is initially proposed to improve the energy conversion efficiency of solar-driven steam methane reforming. A numerical analytical model of solar thermochemical reaction is developed by Monte Carlo raying method combined with thermochemical reaction kinetics. The results show that the biomimetic human ear solar thermochemical reactor can effectively regulate the radiative intensity and temperature field to match the minimum Gibbs free energy principle, which in turn can obtain the methane conversion efficiency of 91.18 % and energy storage efficiency of 60.42 %, while the maximum improvement of solar-to-fuel conversion efficiency and hydrogen generation rate can reach 6.86 % and 20.67 % respectively.
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- 2023
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36. Impact of comorbidity on tolerability and survival following curative intent intensity modulated radiotherapy in older patients with nasopharyngeal cancer.
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Sommat, Kiattisa, Yit, Nelson Ling Fung, Wang, Fuqiang, and Lim, John Heng Chi
- Abstract
Objective This study aimed to evaluate the predictive factors for survival and acute toxicities in older patients with NPC treated with curative intent IMRT. Materials and Methods Older patients aged 65 years and above with non-metastatic NPC treated with curative intent IMRT between 2003 and 2013 were retrospectively analysed. Variables examined were gender, age, overall stage, chemotherapy use, Eastern Cooperative Oncology Group (ECOG) performance status and comorbidity. The comorbidity severity was determined by adult comorbidity evaluation (ACE-27). We considered hospitalization or placement of feeding tube during and up to one month post radiotherapy as surrogate endpoint for significant acute toxicities. Other endpoints examined were: OS (overall survival), DFS (disease free survival), DSS (disease specific survival). Results A total of 185 patients were eligible for analysis. Median age was 70 (65–86 years). Most of the patients presented with Stage III and IVA/B ( n = 127, 68.7%), of good performance status of ECOG 0–1 ( n = 176, 95.1%) and had low comorbidities with ACE-27 score of 0–1 ( n = 141, 76.2%). Chemotherapy was delivered to 84 patients (45.4%). OS, DFS, and DSS were 64.5%, 51.4%, and 72.8% respectively. High comorbidity burden but not chemotherapy had significant impact on OS and DFS in patients with advanced stage. Fifty patients (27%) required tube feeding or hospitalization during the course of RT. Males, chemotherapy use and ECOG score ≥2 were significant predictors of tube feeding or hospitalization during RT. Conclusion Curative IMRT was associated with excellent survival outcomes in older patients with NPC. Comorbidity but not chemotherapy was associated with prognosis in advanced stage. Careful monitoring and intensive support should be instituted in older males with ECOG score ≥2 receiving chemo-radiotherapy. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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37. The Learning Curve for Robotic McKeown Esophagectomy in Patients With Esophageal Cancer.
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Zhang, Hanlu, Chen, Longqi, Wang, Zihao, Zheng, Yu, Geng, Yingcai, Wang, Fuqiang, Liu, Dan, He, Andong, Ma, Lin, Yuan, Yong, and Wang, Yun
- Abstract
Background Robot-assisted McKeown esophagectomy is a promising but technically demanding procedure; thus, a learning curve should be defined to guide training and allow implementation of this technique. Methods This study retrospectively reviewed the prospectively collected data of 72 consecutive patients undergoing robot-assisted McKeown esophagectomy by a single surgical team experienced in open and thoracolaparoscopic esophagectomy. The cumulative sum method was used to analyze the learning curve. Patients were divided into two groups in chronological order, defining the surgeon’s early (group 1: the first 26 patients) and late experience (group 2: the next 46 patients). Demographic data, intraoperative characteristics, and short-term surgical outcomes were compared between the two groups. Results Cumulative sum plots revealed decreasing thoracic and abdominal docking time, thoracic and abdominal console time, and total surgical time after patient 9, 16, 26, 14, and 26, respectively. The mean number of lymph nodes resected was greater in group 2 than in group 1 (22.6 ± 8.2 vs 17.4 ± 6.7, p = 0.008). No other clinic or pathologic characteristics were observed as significantly different. Conclusions For a surgeon experienced in open and thoracolaparoscopic esophagectomy, experience of 26 cases is required to gain early proficiency of robot-assisted McKeown esophagectomy. A learning curve for robot-assisted esophagus dissection would require operations on 26 patients and stomach mobilization would require operations on 14 patients. For the tableside assistant, experience of at least nine cases is needed to achieve an optimal technical level for thoracic docking and 16 cases for abdominal docking. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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38. Effects of earthworms and effective microorganisms on the composting of sewage sludge with cassava dregs in the tropics
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Wang, Fuqiang, Wang, Haihua, Li, Sennan, and Diao, Xiaoping
- Abstract
ABSTRACTThe present study revealed the role of earthworm-effective microorganisms (EM) in converting sewage sludge and cassava dregs into a valuable product. Sewage sludge was toxic to earthworm, therefore it was mixed with cassava dregs in 80:20 proportions (dry weight). Treatments included mixed substrate inoculated versus not inoculated with EM and treated with or without earthworms. The pH, total organic carbon, total nitrogen, and C:N ratio decreased from the initial measurements in the range of 17.43–18.46%, 25.48–33.82%, 19.60–25.37%, and 6.68–14.05% respectively; but electrical conductivity and available phosphorus increased in the range of 113.47–158.16% and 42.42–57.58%, respectively. In addition, they interactively increased total phosphorus from 19.84–63.01% and potassium from 16.41–50.78%, and decreased the polycyclic aromatic hydrocarbons content of substrate from 21.17% to 32.14% with an increase in earthworms from 51.71 to 57.69, respectively. Earthworms and EM could be used together as an efficient method for co-composting sewage sludge plus cassava dregs in the tropics. This could be expected to result in stabilization of waste, increase in nutrients, and reduction of pollutant content.Implications: The first reports of interaction of earthworms and effective microorganisms in the treatment of sewage sludge and cassava dregs in the tropics. Co-composting was an efficient technology for treating sewage sludge and cassava dregs at the same time, in the tropics. The survival rate of the earthworms both> 95%, the highest number of cocoons (640.33) and hatchlings (4694.33) both in EW+EM (Earthworms added and EM inoculated) treatment. Earthworms and EM (Only EM inoculated) interactively increased total phosphorus and potassium content, and decreased the PAH content of substrate with increase in earthworms.
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- 2019
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39. Evaluation of management level of water conservancy construction supervision unit based on variable weight fuzzy theory
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Wang, Bo, Fan, Tianyu, Liu, Mengqi, Wang, Fuqiang, and Nie, Xiangtian
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This paper establishes an evaluation index system for the management level of water conservancy construction supervision units. For the problem that the analytic hierarchy process (AHP) cannot provide more reasonable weights, the idea of variable weight processing is introduced. Variable weight processing is based on the AHP to determine the constant weight vector of evaluation indexes. This paper studies the evaluation of the management level of water conservancy construction supervision units based on the variable weight fuzzy theory, and finally proves the rationality and effectiveness of the method with examples.
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- 2019
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40. HR water consumption marginal benefits and its spatial–temporal disparities in Henan Province, China
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Lü, Subing, Yang, Huan, Wang, Fuqiang, and Kang, Pingping
- Abstract
Water is one of the essential resources to production and living. Agriculture, industry, and living are considered as the direct water consumption. This paper employs the concept of marginal product value to estimate the water consumption marginal benefits in Henan Province. We use data on agricultural water consumption, industrial water consumption, and domestic water consumption of 18 cities in Henan Province surveyed from 2006 to 2013 and considered the Cobb–Douglas production function. The results showed that, during the study period, except for the marginal benefit of agriculture in high developed area, the industrial and domestic water use increased, and the industrial and domestic water use benefits were much higher than agricultural. At the same time, the benefit of the developed area was higher than the developing area. The benefits of agricultural water consumption and industrial water consumption in high developed area have made great improvements gradually, while benefits in low developed area have made small changes; but the benefits of domestic water consumption presented the opposite trend. For the moment, the water consumption marginal benefit still has climbing space. The results are needed for determining the ways in which scarce water resources could be assigned to different areas and sectors.
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- 2018
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41. The microstructure and three-point bending behavior of Ni–Co/WC composite cladding coating
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Yang, Guirong, Song, Wenming, Li, Jian, Wang, Fuqiang, Ma, Ying, and Hao, Yuan
- Abstract
Ni–Co/WC composite coating was fabricated on ZG45 steel substrate through vacuum sintering cladding technology. Its microstructure, composition, and three-point bending behavior were analyzed through scanning electron microscopy, electron probe microanalysis, X-ray diffraction, and mechanical testing. Results show that the distribution of WC particles presents a 3D net-like shape. A metallurgical fusion area is observed at the interface between the composite coating and the substrate. The entire coating consists of a composite coating area, a transition area, and a diffusion fusion area. The main phases of the coating are WC, Cr7C3, Cr23C6, Ni3Si, FeNi3, and Ni–Co solid solution. Three-point bending results reveal that the softness coefficient of the whole sample when the composite coating was in a compressive stress state was larger than that when the composite coating was in a tensile stress state. The bending strength of the sample is 520 MPa when the composite coating is in a compressive stress state. This value is 66 % higher than that when the composite coating is located at the bottom. The cracks simultaneously extend to the substrate and interface when the composite coating was in a compressive stress state and to the substrate when the composite coating was in a tensile stress state. The fracture of the composite area is brittle, and the substrate fracture is ductile.
- Published
- 2018
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42. Analysis of spatial-temporal evolution of agricultural drought based on regional agricultural drought index
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Wang, Fuqiang, Sun, Meiqi, Lü, Subing, and Zhou, Zuhao
- Abstract
In recent years, the frequency and intensity of drought in China are on the rise, and most of the major grain producing provinces are situated in the drought-prone areas, so agricultural drought has become one of the main factors restricting the agricultural production in China. In this paper, with Henan province being taken as the research area, the change trend of agricultural drought area of Henan province was analyzed, and the spatial-temporal evolution characteristics of Henan province were evaluated based on the regional agricultural drought index. The research showed that the inter-annual change of agricultural drought index showed a decreasing trend year by year (tendency rate was –0.12/10a), indicating that the drought degree decreased year by year. The east and south of North Henan, east and north of Eastern Henan, and north and east of Central Henan were mild drought-prone areas; the east of Western Henan, west and north of North Henan, and west of Central Henan were moderate drought-prone areas; the west of North Henan, west of Western Henan, and north of South Henan were severe drought-prone areas. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creative commons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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- 2018
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43. Driving factors of the evolution of groundwater level in People’s Victory Canal Irrigation District, China
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Liu, Zhongpei, Zhao, Yuting, Han, Yuping, Wang, Chunying, and Wang, Fuqiang
- Abstract
It is an efficient way of dynamic characteristics and driving factors analyses of groundwater system to make clear of groundwater cycle and its influence degree by anthropogenic activities. First of all, the temporal and spatial variation law of groundwater level was analyzed based on the measured data of groundwater level in People’s Victory Canal Irrigation District in 1993–2013; then, the influence degree of each influencing factor on the groundwater level was quantified by using correlation analysis; finally, the dominant driving factors influencing the evolution of groundwater level were determined using grey relational analysis. The results show that the groundwater level decreased with the decrease of precipitation, and decreased with the decrease of irrigation water from the Canal, and decreased with the increase of groundwater exploitation. Human activities played a dominant role in the variation of groundwater, and the irrigation water of wells as well as the mining of groundwater for living and industrial use was the dominant driving factors of the variation of groundwater level in the study area.
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- 2018
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44. An evaluation of the ecological security of the Dongting Lake, China
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Wang, Fuqiang, Zhang, Ruijia, Kang, Pingping, and Zhao, Heng
- Abstract
Evaluation of lake ecological security is important for sustainable management of lakes and regional ecological environment construction. Dongting Lake is the second largest freshwater lake in China; its ecological security directly threatens the ecological security of the middle and lower reaches of the Yangtze River. In this paper, the ecological security evaluation index system of the Dongting Lake is constructed, including target layer (first order), criterion layer (second order), and index layer (last order). The target layer is the ecological security of the lake, the standard layer includes five indicators, and the index layer includes 11 indicators. The comprehensive evaluation method is used to evaluate the ecological security of the Dongting Lake by assessing all indexes of every layer. The weight of each index is determined by analytic hierarchy process. The evaluation results showed that the ecological security score of the Dongting Lake is 58 points, belonging to sub-security level. At present, the Dongting Lake has problems of low ecological water level, reduced lake surface area, eutrophication, and reduced lake storage capacity. Therefore, in future, the industrial and domestic pollution sources should be controlled, and the carrying capacity of water environment should be improved.
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- 2018
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45. Robot-assisted thoracic surgery for apex-located neurogenic tumors.
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Wang, Fuqiang, Zhang, Hanlu, Qiu, Guanghao, and Wang, Yun
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- 2022
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46. Heavy metals in the sediments of Laoshan Bay, China: Distribution and contamination assessment.
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Tian, Xu, Xu, Weikun, Wang, Fuqiang, Ye, Youquan, Liu, Ming, Shi, Honghua, Fan, Dejiang, and Xu, Fangjian
- Subjects
HEAVY metals ,NUCLEOSYNTHESIS ,SEDIMENT sampling ,SEDIMENTS ,FOSSIL fuels ,ORGANIC compounds - Abstract
We analyzed total organic carbon (TOC), total nitrogen (TN), and heavy metals in 58 sediment samples from the Laoshan Bay, China. TOC and TN results identified marine primary production as the dominant source for organic matter, and the weak correlations between TOC, TN, and heavy metals indicated the terrestrial origin of heavy metals. Cd showed insignificant correlations with other metals, which suggests that agriculture production is the main anthropogenic activity affecting the distribution of Cd. Pb contamination in past 50 years was likely to have occurred because of fossil fuel combustion. Despite
210 Pb dating, it was still difficult to trace the contamination condition over interannual variations. Nonetheless, these results provide data for monitoring Pb contamination. As Laoshan Bay is an important economic area, it would be beneficial to conduct further studies to determine the sources and degree of contamination for each heavy metal. • Heavy metal distribution and contamination were assessed in Laoshan Bay, China. • Heavy metals were mainly sourced from land. • Low I geo values for some elements indicated their origin from natural sources. • High EF and I geo values of Pb suggested indicated its anthropogenic origin. [ABSTRACT FROM AUTHOR]- Published
- 2022
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47. Effects of dietary cadmium on growth, antioxidants and bioaccumulation of sea cucumber (Apostichopus japonicus) and influence of dietary vitamin C supplementation.
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Wang, Jing, Ren, Tongjun, Wang, Fuqiang, Han, Yuzhe, Liao, Mingling, Jiang, Zhiqiang, and Liu, Haiying
- Subjects
SEA cucumbers ,ECHINODERMATA growth ,PHYSIOLOGICAL effects of cadmium ,BIOACCUMULATION ,VITAMIN C in animal nutrition ,DIETARY supplements ,PHYSIOLOGY - Abstract
The effects of dietary cadmium (Cd) supplementation on growth, antioxidant capacity and accumulation of Cd in tissues (body wall, digestive tracts, and respiratory tree) of sea cucumber, Apostichopus japonicus , exposed to sub-chronic concentrations (0, 10, 50, 100, and 500 mg Cd/kg dry weight) of Cd were investigated. In addition, the potential protective effects of vitamin C (L-ascorbic acid, AsA) against the effects of Cd on sea cucumbers were investigated. Sea cucumbers were exposed to dietary Cd for 30 days, after which another group of healthy sea cucumbers was supplied diet supplemented with mixed Cd and AsA for another 30 days. Cd exposure for 30 days resulted in increased Cd accumulation in tissues of sea cucumbers with exposure time and concentration. The order of Cd accumulation in organs was digestive tracts>respiratory tree>body wall. On day 30, the body weight gain (BWG) and specific growth rate (SGR) decreased significantly ( P <0.05) in the 500 mg Cd/kg treatment. Superoxide dismutase (SOD) activity, glutathione peroxidase (GSH-Px) activity and catalase (CAT) activity in the coelomic fluid of sea cucumbers decreased with increasing dietary Cd concentration, but malondialdehyde (MDA) content in the coelomic fluid increased. Providing diet supplemented with Cd and AsA indicated that although sea cucumbers exhibited signs of Cd toxicity, no death occurred in response to 50 mg Cd/kg for 30 days. Based on these findings, five treatments were provided: 50 mg Cd/kg+0 mg AsA/kg, 50 mg Cd/kg+ 3000 mg AsA/kg, 50 mg Cd/kg+ 5000 mg AsA/kg, 50 mg Cd/kg+10,000 mg AsA/kg, and 50 mg Cd/kg+15,000 mg AsA/kg. The BWG and SGR of sea cucumbers fed the AsA supplemented diet mixed with Cd increased. Additionally, MDA levels in coelomic fluid were negatively correlated with dietary AsA levels, while antioxidant capacities (SOD, GSH-Px and CAT) were positively correlated with dietary AsA levels. Moreover, Cd accumulation in tissues decreased in response to dietary AsA supplementation of treatments. Overall, antioxidant capacity and bioaccumulation in sea cucumber was found to decrease and be induced in response to Cd, but vitamin C mitigated these effects, with 5000 mg AsA/kg providing the optimum protection against 50 mg/kg Cd. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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48. Polycyclic aromatic hydrocarbons in surface sediment from Yangpu Bay, China: Distribution, sources and risk assessment.
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Li, Ping, Diao, Xiaoping, Zhang, Yu, Xie, Yanli, Yang, Fei, Zhou, Hailong, Han, Qian, Wang, Fuqiang, Cheng, Huamin, and Wang, Haihua
- Subjects
POLYCYCLIC aromatic hydrocarbons ,MARINE sediments ,OCEAN temperature ,ENVIRONMENTAL risk assessment - Abstract
The study investigated the occurrence of polycyclic aromatic hydrocarbons (PAHs) in the surface sediment from eleven sites in Yangpu Bay, China in December 2013 (winter) and July 2014 (summer). The 16 US EPA priority PAHs were found in the range of 1583.2–5701.7 ng/g dry weights with an average of 3134.7 ± 1241.3 ng/g in winter and ranged from 2161.8 to 4527.2 ng/g with an average of 3016.6 ± 748.0 ng/g in summer, respectively. The concentrations of the PAHs tended to be relatively high in comparison with other areas from the literatures. The identification using molecular indices analysis indicated that the PAHs originated mainly from pyrogenic and petrogenic sources in most of the sites. According to principle component analysis–multiple linear regression (PCA/MLR) for their source apportionment, the main sources of PAHs were vehicle emissions, petroleum products and biomass combustion. The risk assessment using international sediments quality guidelines and sediments quality criteria indicated that several PAHs, such as Nap, Flu, Phe, Ace, Acy and BghiP in most of the sites would potentially affect organisms in Yangpu Bay. [ABSTRACT FROM AUTHOR]
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- 2015
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49. Effect of collisional energy loss on particle correlations in AMPT
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Wang, Fuqiang, Edmonds, Terrence, and Li, Qingfeng
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Jet quenching is a powerful tool to study medium properties of relativistic heavy ion collisions via jet-medium interactions. Jet quenching studies have so far focused on high transverse momentum (pT) particle suppression. Jet shapes at low to intermediate pT, containing rich information on jet-medium interactions, have been less explored. In this talk, I will present a recent study, using a multiphase transport (AMPT) model, of effects on particle correlations from collisional energy loss of partons traversing the heavy ion medium. We follow the parton cascading history so that medium partons (associated particles) which have interacted with a high-pTprobe parton (hard probe trigger particle) can be uniquely identified and hence no subtraction of combinatorial background is needed. Results on particle correlation shapes will be presented as a function of pT, the number of parton-parton collisions suffered by the probe parton, and the azimuthal angle of the probe parton relative to the reaction plane. These results reveal pathlength dependence of collisional energy loss.
- Published
- 2017
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50. Extensible time synchronisation protocol for wireless sensor networks
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Wang, Fuqiang, Wu, Xiaoming, Wang, Yinglong, Zeng, Peng, and Xiao, Yang
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One important aspect in many applications of wireless sensor networks (WSNs) is time synchronisation. There are still some problems to be solved for time synchronisation, such as error and imbalance of time synchronisation precision, causing the fluctuations among nodes' time and being even worse for those with a larger number of hops, producing unstable communication links for the network. In this paper, we introduce an extensible time synchronisation protocol (ETSP) for WSNs and nodes get synchronised through time stamps from the root node directly or indirectly. We improve the least square method for linear regression to get better performance of time drift and spread the time information from the root node to the whole network. The proposed method reduces fluctuations in terms of time among nodes especially for the nodes far from the root, enhancing stability in large-scale networks. Simulation and experimental results show good performance of our method.
- Published
- 2017
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