Search

The technology of combining multiple emission centers to exploit white-light-emitting (WLE) materials by taking advantage of porous metal–organic frameworks (MOFs) is mature, but preparing undoped WLE MOFs remains a challenge. Herein, a pressure-treated strategy is reported to achieve efficient white photoluminescence (PL) in undoped [Zn(Tdc)(py)]nnanocrystals (NCs) at ambient conditions, where the Commission International del’Eclairage coordinates and color temperature reach (0.31, 0.37) and 6560 K, respectively. The initial [Zn(Tdc)(py)]nNCs exhibit weak-blue PL consisting of localized excited (LE) and planarized intramolecular charge transfer (PLICT) states. After pressure treatment, the emission contributions of LE and PLICT states are balanced by increasing the planarization of subunits, thereby producing white PL. Meanwhile, the reduction of nonradiative decay triggered by the planarized structure results in 5-fold PL enhancement. Phosphor-converted light-emitting diodes based on pressure-treated samples show favorable white-light characteristics. The finding provides a new platform for the development of undoped WLE MOFs.

Chitin-degrading enzymes are critical components in regulating the molting process of the Asian corn borer and serve as potential targets for controlling this destructive pest of maize. Here, we used a scaffold-hopping strategy to design a series of efficient naphthylimide insecticides. Among them, compound 8cexhibited potent inhibition of chitinase from OfChi-h and OfChtI at low nanomolar concentrations (IC50= 1.51 and 9.21 nM, respectively). Molecular docking simulations suggested that 8cbinds to chitinase by mimicking the interaction of chitin oligosaccharide substrates with chitinase. At low ppm concentrations, compound 8cperformed comparably to commercial insecticides in controlling the highly destructive plant pest, the Asian corn borer. Tests on a wide range of nontarget organisms indicate that compound 8chas very low toxicity. In addition, the effect of inhibitor treatment on the expression of genes associated with the Asian corn borer chitin-degrading enzymes was further investigated by quantitative real-time polymerase chain reaction. In conclusion, our study highlights the potential of 8cas a novel chitinase-targeting insecticide for effective control of the Asian corn borer, providing a promising solution in the quest for sustainable pest management.

Following percutaneous coronary intervention with stent placement to treat acute coronary syndromes, international clinical guidelines generally recommend dual antiplatelet therapy with aspirin plus a P2Y12receptor inhibitor for 12 months to prevent myocardial infarction and stent thrombosis. However, data on single antiplatelet therapy with a potent P2Y12inhibitor earlier than 12 months after percutaneous coronary intervention for patients with an acute coronary syndrome are scarce. The aim of this trial was to assess whether the use of ticagrelor alone, compared with ticagrelor plus aspirin, could reduce the incidence of clinically relevant bleeding events without an accompanying increase in major adverse cardiovascular or cerebrovascular events (MACCE).

Intravascular ultrasound-guided percutaneous coronary intervention has been shown to result in superior clinical outcomes compared with angiography-guided percutaneous coronary intervention. However, insufficient data are available concerning the advantages of intravascular ultrasound guidance for patients with an acute coronary syndrome. This trial aimed to investigate whether the use of intravascular ultrasound guidance, as compared with angiography guidance, improves the outcomes of percutaneous coronary intervention with contemporary drug-eluting stents in patients presenting with an acute coronary syndrome.

Insect growth regulators (IGRs) are important green insecticides that disrupt normal growth and development in insects to reduce the harm caused by pests to crops. The ecdysone receptor (EcR) and three chitinases OfChtI, OfChtII, and OfChi-h are closely associated with the molting stage of insects. Thus, they are considered promising targets for the development of novel insecticides such as IGRs. Our previous work identified a dual-target compound 6j, which could act simultaneously on both EcR and OfChtI. In the present study, 6jwas first found to have inhibitory activities against OfChtII and OfChi-h, too. Subsequently, taking 6jas a lead compound, 19 novel acetamido derivatives were rationally designed and synthesized by introducing an acetamido moiety into the amide bridge based on the flexibility of the binding cavities of 6jwith EcR and three chitinases. Then, their insecticidal activities against Plutella xylostella(P. xylostella), Ostrinia furnacalis(O. furnacalis), and Spodoptera frugiperda(S. frugiperda) were carried out. The bioassay results revealed that most of these acetamido derivatives possessed moderate to good larvicidal activities against three lepidopteran pests. Especially, compound I-17displayed excellent insecticidal activities against P. xylostella(LC50, 93.32 mg/L), O. furnacalis(LC50, 114.79 mg/L), and S. frugiperda(86.1% mortality at 500 mg/L), significantly better than that of 6j. In addition, further protein validation and molecular docking demonstrated that I-17could act simultaneously on EcR (17.7% binding activity at 8 mg/L), OfChtI (69.2% inhibitory rate at 50 µM), OfChtII (71.5% inhibitory rate at 50 µM), and OfChi-h (73.9% inhibitory rate at 50 µM), indicating that I-17is a potential lead candidate for novel multitarget IGRs. This work provides a promising starting point for the development of novel types of IGRs as pest management agents.

SiCf/Ti2AlNb-reinforced Ti17 (SiCf/Ti2AlNb/Ti17) composites were fabricated through hot isostatic pressing. The designed SiCf/Ti2AlNb/Ti17 composites exhibited excellent tensile properties, with tensile strengths of 1657 MPa at room temperature and 1830 MPa at 450 °C. The microstructure, fracture morphology, and longitudinal section of the composites were characterized by X-ray diffraction, scanning electron microscopy, and electron backscatter diffraction techniques. The fracture process of SiCf/Ti2AlNb/Ti17 composites during room-temperature tensile tests was as follows: the SiCf/Ti2AlNb reaction layer first fractured, the crack extended into the Ti2AlNb matrix, the Ti2AlNb matrix crack extended to the adjacent reaction layer and promoted fiber fracture, the crack extended to the Ti2AlNb/Ti17 interface, ultimately the Ti17 capsule fractured. The fracture process of SiCf/Ti2AlNb/Ti17 composites during 450 °C tensile tests was as follows: the SiCf/Ti2AlNb reaction layer first fractured, multiple fiber fractures occurred, and the crack in the reaction layer entered the Ti2AlNb matrix, the crack extended to the Ti2AlNb/Ti17 interface, eventually the Ti17 capsule fractured. The room-temperature tensile fracture was fitted to the LLS model, while the tensile fracture at 450 °C was fitted to the GLS model. The different fracture processes indicated that the SiCf/Ti2AlNb/Ti17 composites were suitable for exploiting fiber strength at 450 °C and therefore exhibited excellent tensile strength.

Microstructure evolution during the hot isostatic pressing (HIP) of continuous silicon carbide fiber-reinforced Ti (SiCf/Ti) composites has not been investigated. In this study, SiCf/Ti60 composites were prepared via the HIP solidification method of Ti60 precursor wires. The evolution of the microstructure of the Ti60 precursor wires and SiCf/Ti60 composites was characterized using electron backscatter diffraction microscopy and transmission electron microscopy techniques. The results showed that the deformation of α-Ti was mainly accomplished by basal dislocations and prismatic dislocations slip during the HIP process. After the completion of HIP, the low-angle grain boundaries (LAGBs) were reduced to 24.6%, and the average grain size of α-Ti was increased to 7.47 μm2. Two fiber textures, <0001>//axial direction (AD) and <10-10>//AD strength, were present in α-Ti, with a 38% increase in <10-10>//AD strength. The phase contents of 1.0% β-Ti and 0.6% (Ti, Zr)6Si3precipitated from different locations in the Ti60 matrix and induced changes in misorientation.

ELVDD provides the anode voltage of OLED. In the OLED pixel circuit, the source electrode of driving TFT is connected to ELVDD, and the drain electrode is connected to the anode of OLED. Most OLED panels of existing mobile phones set the ELVDD voltage to 4.6V.However, some OLED panels of new mobile phones set the ELVDD to 2.8V for energy‐saving purposes. As an important measure to reduce the logic power consumption of OLED display panel, ELVDD 2.8V setting is more and more common in mobile OLED panel design. Based on an OLED mobile phone panel, the comparison test of ELVDD setting 4.6V and 2.8V is carried out.

To investigate the effect of acupuncture onset time and synaptic structure in two different models of depression.

Ferroptosis, as a new form of regulated cell death, is implicated in various physiological and pathological processes. Developing a single probe for an independent analysis of multiple analytes related to ferroptosis can provide more accurate information and simplify the detection procedures, but it faces great challenges. In this work, we develop a fluorescent probe for the simultaneous detection of GSH through ratiometric fluorescence response and microviscosity via a fluorescence lifetime model. Based on the reversible Michael addition reaction between GSH and unsaturated C═C bond, the probe responds reversibly to GSH with a ratiometric fluorescence variation and a fast response time (t1/2= 4.7 s). At the same time, the probe is sensitive to environmental viscosity by changing its fluorescence lifetimes. The probe was applied to monitor the drug-induced ferroptosis process through both the classical Xc–/GSH/GPX4- and DHODH-mediated defense mechanisms. We hope that the probe will provide a useful molecular tool for the real-time live-cell imaging of GSH dynamics, which is benefit to unveiling related physiological and pathological processes.

OfChtI and OfChi-h are considered potential targets for the control of Asian corn borer (Ostrinia furnacalis). In this work, the previously reported OfChtI inhibitor 5fwas found to show certain inhibitory activity against OfChi-h (Ki= 5.81 μM). Two series of novel butenolide derivatives based on lead compound 5fwere designed with the conjugate skeleton, contributing to the π-binding interaction to chitinase, and then synthesized. Compounds 4a–land 7a–pdisplayed excellent inhibitory activities against OfChtI and OfChi-h, respectively, at a concentration of 10 μM. Compound 4hwas found to be a good dual-Chitinase inhibitor, with Kivalues of 1.82 and 2.00 μM against OfChtI and OfChi-h, respectively. The inhibitory mechanism studies by molecular docking suggested that π–π stacking interactions were crucial to the inhibitory activity of novel butenolide derivatives against two different chitinases. A preliminary bioassay indicated that 4hexhibited certain growth inhibition effects against O. furnacalis. Butenolide-like analogues should be further studied as promising novel dual-chitinase inhibitor candidates for the control of O. furnacalis.

Locust mandibles have stiff cuticles to process rough food. Therefore, the mandible is a reservoir of stiff structural proteins (SPs). Here, LmCPH-1, the most abundant SP in locust mandibles, is reported to be an indispensable stiff SP in mandibles. In vivo, suppression of LmCPH-1 expression seriously weakens the mechanical properties of the mandible. In vitro, LmCPH-1 undergoes hierarchical self-assembly to form a film with an ultrahigh modulus (12 GPa), which outperforms most protein-based materials. The stiffness of LmCPH-1 film can be attributed to its high β-sheet/β-crystal content formed through self-assembly. Molecular dynamics simulations indicate that the C-terminal region of LmCPH-1 plays a vital role in its self-assembly process. We conclude that LmCPH-1 strengthens the locust mandible by forming a stiff cement to fill the chitin scaffold. The findings not only represent a universal reinforcing mechanism of insect cuticle but also provide a potent starting material for sustainable materials.

The metallurgical quality control of magnesium (Mg) and Mg alloys in melting process is required to ensure a satisfied mechanical and corrosion performance, while the typical used steel crucible introduces impurities and interfacial interaction during melting process. Therefore, a systematic study about impurities diffusion and interfacial interaction between molten Mg and steel is necessary. In the present study, the interfacial reaction between molten AZ91D Mg alloy and mild steel during melting process was investigated with the melting temperatures of 700 °C, 750 °C and 800 °C. The results show that Al(Fe, Mn) intermetallic layer is the intermetallic primarily formed at the interfaces of AZ91D melt and mild steel. Meanwhile, Al8(Mn, Fe)5is indexed between Al(Fe, Mn) and AZ91D. AlFe3C appears between the mild steel and Al(Fe, Mn) at 700 °C and 750 °C, but absent at 800 °C due to the increased solubility of carbon in Mg matrix. It is found that the growth of the intermetallic layer is controlled by diffusion mechanism, and Al and Mn are the dominant diffusing species in the whole interfacial reaction process. By measuring the thickness of different layers, the growth constant was calculated. It increases from 1.89(±0.03)×10−12m2·s−1at 700 °C to 3.05(±0.05)×10−12m2·s−1at 750 °C, and 5.18(±0.05)×10−12m2·s−1at 800 °C. Meanwhile, the content of Fe is linearly increased in AZ91D with the increase of holding time at 700 °C and 750 °C, while it shows a significantly increment after holding for 8 h at 800 °C, indicating holding temperature is more crucial to determine the Fe content of AZ91D than holding time.

The objective of this study was to examine the relationship between the variables of the value-belief-norm (VBN) theory and the adoption of green consumption behaviors among Chinese youth. The online survey questionnaire was distributed to a convenience sample of young Chinese consumers aged 18–35 years through the platforms WJX and WeChat. The data collection period spanned from September to December 2022. The analysis involved a total of 1074 participants, and the statistical technique employed was partial least squares structural equation modeling (PLS-SEM) using Smart-PLS 4.0. Common-method bias, multivariate normality, validity, and reliability were also assessed. The results revealed that biospheric values (BV), altruistic values (AV), the new ecological paradigm (EP), awareness of consequences (AC), the ascription of responsibility (AR), and personal norms (PN) significantly and positively influenced intention toward green consumption practices (IGP), which, in turn, had a significant positive influence on the adoption of green consumption practices (AGP). Additionally, GT did not moderate the association between IGP and AGP. This study contributes to the literature on green consumption by analyzing VBN theory’s influence on Chinese youth’s behavior toward green consumption practices to understand and promote green behavior. This study’s findings suggest that promoting ecological awareness and responsibility, developing green values and trust, and strengthening personal norms can encourage green consumption practices among Chinese youth. Policymakers, businesses, and marketers can benefit from these findings to promote green consumption and sustainability in China.

Let BHbe a fractional Brownian motion with Hurst index 12≤H<1. In this paper, we consider the equation (called the Ornstein-Uhlenbeck process with a linear self-repelling drift) dXtH=dBtH+σXtHdt+νdt−θ(∫0t(XtH−XsH)ds)dt,where θ < 0, σ, v∈ ℝ. The process is an analogue of self-attracting diffusion (Cranston, Le Jan. Math Ann, 1995, 303: 87–93). Our main aim is to study the large time behaviors of the process. We show that the solution XHdiverges to infinity as t tends to infinity, and obtain the speed at which the process XHdiverges to infinity as ttends to infinity.

Separating ethane (C2H6) from ethylene (C2H4) is an essential and energy-intensive process in the chemical industry. Here, we report two flexible diamondoid coordination networks, X-dia-1-Niand X-dia-1-Ni0.89Co0.11, that exhibit gate-opening between narrow-pore (NP) and large-pore (LP) phases for C2H6, but not for C2H4. X-dia-1-Ni0.89Co0.11thereby exhibited a type F–IV isotherm at 273 K with no C2H6uptake and a high uptake (111 cm3g–1, 1 atm) for the NP and LP phases, respectively. Conversely, the LP phase exhibited a low uptake of C2H4(12.2 cm3g–1). This C2H6/C2H4uptake ratio of 9.1 for X-dia-1-Ni0.89Co0.11far surpassed those of previously reported physisorbents, many of which are C2H4-selective. In situvariable-pressure X-ray diffraction and modeling studies provided insight into the abrupt C2H6-induced structural NP to LP transformation. The promise of pure gas isotherms and, more generally, flexible coordination networks for gas separations was validated by dynamic breakthrough studies, which afforded high-purity (99.9%) C2H4in one step.

The operation efficiency of the manipulator is placed in the primary position in automatic production. This paper proposes a coordinated control strategy for joint servo and visual servo to enable timely transfer and accurate gripping in the working area. Aiming at the issues of chattering and slow convergence of traditional sliding mode controller, a fast variable power reaching rate on the basis of the non-singular fast terminal sliding mode controller is proposed, which can effectively reduce the convergence time and chattering. For the purpose of addressing the problem that the traditional visual servo control method is sensitive to the environment, a visual servo controller based on integral sliding mode is proposed, to ensure the favorable positioning accuracy of the manipulator. Based on the two proposed controllers mentioned above, a coordinated control strategy is used to implement the control of the manipulator. Finally, the upper computer software is developed using the C# programming language to monitor the workstation. The feasibility of the above-mentioned method is verified through multiple simulations and experiments.

An effective Ag(I)-mediated annulation of 2-(2-enynyl)pyridines and propargyl amines was developed, unexpectedly affording a broad range of functionalized 1-(2H-pyrrol-3-yl)indolizines in moderate to excellent yields. The developed method is characterized by operational simplicity, ready availability of starting materials, high regioselectivity, and broad substrate scope under mild reaction conditions. The Ag(I)-promoted cyclization of 2-(2-enynyl)pyridines and propargyl amines possibly results in the formation of the spiroindolizine, the ring-opening rearrangement of which may give the 1-(2H-pyrrol-3-yl)indolizine. Furthermore, a gram-scale reaction and synthetic transformations are also studied.

Localization and tracking are important components for ground-moving target indication (GMTI). The traditional range-Doppler (RD) localization model is always applied to locate stationary targets in bistatic synthetic aperture radar (BiSAR). However, for moving targets, this localization model is no longer applicable due to the strong coupling of position and velocity with Doppler frequency. To address the severe challenge, this article proposes a joint moving target localization and tracking method for BiSAR-GMTI via transmitter–receiver trajectories extraction and inversion. The key innovation is the derivation of closed-form localization results for moving targets, which is beneficial for the quantitative analysis of localization error. The proposed method is structured into three main parts. First, to accurately capture the range history trajectory information, a segmented fitting extraction and inversion framework is designed. Second, to estimate the moving target’s initial state and demonstrate localization observability, joint range localization equations are established where the closed-form localization result of the moving target is derived. Finally, by defining the appropriate state transition equation and observation equation, and incorporating particle filtering (PF), the position measurement errors of bistatic platforms are weakened, and accurate tracking of moving targets is realized. The proposed method only utilizes range information, mitigating localization errors caused by Doppler estimation inaccuracies effectively. Simulation experiments and real data both demonstrate the localization and tracking accuracy of moving targets.