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Résumé Depuis la parution de la loi de bioéthique de 2004, la préservation de la fertilité fait partie du parcours de soins des patientes devant être traitées par des chimiothérapies et/ou radiothérapie et/ou chirurgie ovarienne gonadotoxiques et des patientes pour lesquelles la fertilité risque d’être prématurément altérée. Il existe plusieurs techniques de préservation de la fertilité féminine, dont trois techniques d’assistance médicale à la procréation : la cryoconservation embryonnaire, d’ovocytes isolés et de cortex ovarien. Le choix de la ou des techniques dépend du type de traitement, des doses et de sa durée, mais aussi de l’âge de la patiente, de son statut marital, de l’urgence de la mise en place de son traitement anticancéreux et de l’hormonosensibilité de la tumeur. Les résultats de ces techniques, dans le cadre de la préservation de la fertilité, sont en pleine évolution et compte tenu d’une utilisation différée des embryons, ovocytes et fragments ovariens cryoconservés, ne sont pas encore définitifs. Since the publication of the Bioethics Act of 2004, the fertility preservation is a part of care of patients that will be treated with gonadotoxic chemotherapy and/or radiotherapy and/or ovarian surgery and of patients with fertility that could be prematurely altered. There are several techniques for preserving female fertility. Three techniques of assisted reproductive biology are possible: embryo cryopreservation, isolated oocytes cryopreservation and ovarian cortex cryopreservation. The choice of the technique(s) depends on the type of treatment, its duration and the doses, but also on the age of the patient, her marital status, the emergency of her anticancer treatment and the hormonosensitivity of the tumor. The results of these techniques of fertility preservation are evolving and given the delayed use of embryos, oocytes and ovarian fragments, are not yet definitive. [ABSTRACT FROM AUTHOR]

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Copyright of Revue de Médecine Vétérinaire is the property of Ecole Nationale Veterinaire de Toulouse and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Abstract: Adult stem cells are characterized by the ability to maintain their population through cell division and concomitantly generate specialized somatic cell types through differentiation. Stem cells generated from the adult pancreas proliferate rapidly in vitro and are able to develop into cell types of all three germ layers . Therefore, these cells are suitable for the application in basic research and applied science. In vitro, cells enable the analysis of various scientific subjects under standardized conditions. For instance, they can be applied to establish species specific test systems and diagnosic tools for the assessment of compounds, like pharmaceuticals and xenobiotics, or pathogens. Also, they can be used to investigate how the aforementioned factors act on the cellular level. The detection of specific proteins provides information about the differentiation potential of stem cells and the vitality of the cells. Alterations of these parameters are applicable for the evaluation and analysis of the effect of exogenic factors on cells and the organism. In cooperation with Hagenbecks Tierpark in Hamburg and the zoological gardens in Rostock and Neunkirchen, the Fraunhofer institution for marine biotechnology (EMB) has initiated the establishment of an archive for proliferative cells from wildlife animals. The tissue specimens for the isolation of the cells originate from deceased animals or placental tissue. The archive is continuously growing. Cells from various wildlife animals are added regularly and are permanently stored and cryoconserved. In this study, we report the cultivation and molecular characterisation of adult proliferative cells from a snow leopard (Uncia uncia). The characterization was performed detecting cell type specific and metabolism related proteins by means of immuncytochemistry. [Copyright &y& Elsevier]

Copyright of IBS, Immuno-analyse & Biologie Specialisee is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)