Search

A recent study conducted in China investigated the relationship between magnetic resonance image (MRI) features and the immunohistochemical subtypes of pituitary microadenomas (PMAs). The research found that different subtypes of PMAs showed locational preferences within the pituitary gland, with somatotroph adenomas (STAs) favoring the lateral-anteroinferior portion, lactotroph adenomas (LTAs) preferring the lateral-posteroinferior portion, and gonadotroph adenomas (GTAs) predominantly located in the central-anteroinferior portion. The study concluded that MRI has the potential to differentiate between different subgroups of PMAs based on their growth patterns, especially in cases where the subtypes are not clearly defined. [Extracted from the article]

Researchers at Kagoshima University in Japan have reported a rare case of intrasellar kissing carotid arteries compressing the pituitary gland, mimicking a pituitary microadenoma. A 61-year-old woman with chronic headaches was found to have a sellar mass that was monitored for 16 years, showing normal hormone levels. Three-dimensional imaging revealed the pituitary gland being squeezed upward by the carotid arteries. This study highlights how anatomical variations can mimic pituitary tumors. [Extracted from the article]

A recent study conducted by researchers at Tishk International University provides new insights into microadenoma, a type of pituitary adenoma. The study focuses on a 53-year-old patient who presented with periorbital edema (swelling around the eyes) and visited a dental clinic to rule out dental infection. Through hematological and radiological investigations, the researchers identified a pituitary microadenoma and an increase in thyroid stimulating hormone (TSH) levels. However, further studies revealed that the swelling was caused by a disruption in the patient's drug regimen, rather than the microadenoma. This case report highlights the importance of thorough evaluation and follow-up in diagnosing and treating periorbital edema associated with hypothyroidism. [Extracted from the article]

A study conducted at the Mayo Clinic in Rochester, Minnesota, has found that pituitary microadenomas, particularly corticotroph adenomas, can be challenging to identify on MRI scans. In some cases, these adenomas may not be visible on MRI, increasing the risk of surgery. However, the use of 7-T MRI and intraoperative ultrasound can provide greater detail and real-time image guidance, aiding in the diagnosis and surgical management of these microadenomas. The study presented a case of Cushing disease where 7-T MRI and intraoperative ultrasound were used to guide the successful endoscopic endonasal resection of a pituitary microadenoma, resulting in significant improvement in symptoms and biochemical cure. The research was published in Operative Neurosurgery and obtained written informed consent from the patient for publication. [Extracted from the article]

According to news reporting originating from Shandong, People's Republic of China, by NewsRx correspondents, research stated, "Mammary duct ectasia is an acute or chronic inflammatory breast disease that occurs mainly in nonlactating women. Keywords: Adenomas; Health and Medicine; Microadenoma; Oncology EN Adenomas Health and Medicine Microadenoma Oncology 6723 6723 1 08/28/23 20230901 NES 230901 2023 SEP 1 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators publish new report on microadenoma. [Extracted from the article]

Adenomas, Adrenal Gland Diseases and Conditions, Adrenocorticotropic Hormones, Cushing's Syndrome, Health and Medicine, Hypothalamic Hormones, Melanocortins, Microadenoma, Nerve Tissue Proteins, Neuropeptides, Oncology, Peptide Hormones, Peptide Proteins, Pituitary Hormones, Pro-Opiomelanocortin Keywords: Adenomas; Adrenal Gland Diseases and Conditions; Adrenocorticotropic Hormones; Cushing's Syndrome; Health and Medicine; Hypothalamic Hormones; Melanocortins; Microadenoma; Nerve Tissue Proteins; Neuropeptides; Oncology; Peptide Hormones; Peptide Proteins; Pituitary Hormones; Pro-Opiomelanocortin EN Adenomas Adrenal Gland Diseases and Conditions Adrenocorticotropic Hormones Cushing's Syndrome Health and Medicine Hypothalamic Hormones Melanocortins Microadenoma Nerve Tissue Proteins Neuropeptides Oncology Peptide Hormones Peptide Proteins Pituitary Hormones Pro-Opiomelanocortin 3080 3080 1 08/28/23 20230901 NES 230901 2023 SEP 1 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators discuss new findings in Cushing's syndrome. [Extracted from the article]

Surgical resection constitutes the first line treatment for pituitary adenomas except for prolactinomas which typically respond well to pharmacological therapy. Pituitary adenomas are generally resected via a tanssphenoidal approach. Using endoscopic technique a gross total resection is typically achieved in 90% of microadenomas (diameter < 1 cm). Surgical resection of pituitary macroadenomas (diameter 1 > cm) is facilitated by the use of angled endoscopes in combination with extended approaches. Thus, a gross total resection is achieved in more than two thirds of pituitary macroadenomas. However, once the tumor has invaded the cavernous sinus, gross total resection is only achieved in one third of patients. In functional pituitary adenomas such as prolactinomas, ACTH producing adenomas and growth hormone producing adenomas endocrinological remission is achieved in approximately 80% of patients. Similarly, remission rates decrease once the adenoma has invaded the cavernous sinus. In conclusion, endoscopic transsphenoidal technique allows for gross total resection in the vast majority of patients. [Copyright &y& Elsevier]