27 results on '"Betzi, Stéphane"'
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2. 4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
3. From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia
4. Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein–Protein Interaction: A Semi-Automated “Hit Identification-to-Optimization” Approach
5. CRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug Modulation
6. CRCM5484: A BET- BDII Selective Compound With Differential Anti-Leukemic Drug Modulation
7. Discovery of small molecule inhibitors of the PTK7/β-catenin inter-action targeting the Wnt signaling pathway in colorectal cancer
8. Revisiting the molecular interactions between the tumor protein TCTP and the drugs sertraline/thioridazine.
9. In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor
10. In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor
11. Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach
12. Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis
13. Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining
14. Author response: Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining
15. Protein–Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery
16. Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins
17. 2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein–protein interactions
18. Coronavirus Nsp10, a Critical Co-factor for Activation of Multiple Replicative Enzymes
19. Structural and Biochemical Characterization of the Cop9 Signalosome CSN5/CSN6 Heterodimer
20. Focused Chemical Libraries – Design and Enrichment: An Example of Protein–Protein Interaction Chemical Space
21. Crystal Structure of the Vaccinia Virus DNA Polymerase Holoenzyme Subunit D4 in Complex with the A20 N-Terminal Domain
22. Prevalence, Specificity and Determinants of Lipid-Interacting PDZ Domains from an In-Cell Screen and In Vitro Binding Experiments
23. Stereoselective synthesis of original spirolactams displaying promising folded structures
24. 2P2Idb: a structural database dedicated to orthosteric modulation of protein–protein interactions
25. Identification of allosteric inhibitors blocking the hepatitis C virus polymerase NS5B in the RNA synthesis initiation step
26. Protein–protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein
27. GFscore: A General Nonlinear Consensus Scoring Function for High-Throughput Docking
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