89 results on '"Cimprich, Karlene A."'
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2. Quantitative DNA–RNA Immunoprecipitation Sequencing with Spike-Ins
3. Author Correction: R-loop-derived cytoplasmic RNA–DNA hybrids activate an immune response
4. HLTF Prevents G4 Accumulation and Promotes G4-induced Fork Slowing to Maintain Genome Stability
5. Direct visualization of transcription-replication conflicts reveals post-replicative DNA:RNA hybrids
6. R-loop-derived cytoplasmic RNA–DNA hybrids activate an immune response
7. Walking a tightrope: The complex balancing act of R-loops in genome stability
8. ATR activity controls stem cell quiescence via the cyclin F–SCF complex
9. Catalytically inactive, purified RNase H1: A specific and sensitive probe for RNA–DNA hybrid imaging
10. Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination–deficient cancer models
11. Abstract IA-003: Oxygen dependent resistance to PARP inhibitors
12. qDRIP: a method to quantitatively assess RNA–DNA hybrid formation genome-wide
13. HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
14. qDRIP: Quantitative differential RNA:DNA hybrid immunoprecipitation sequencing
15. R-Loops as Cellular Regulators and Genomic Threats
16. PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis
17. An intrinsic S/G 2 checkpoint enforced by ATR
18. Stochastic Endogenous Replication Stress Causes ATR-Triggered Fluctuations in CDK2 Activity that Dynamically Adjust Global DNA Synthesis Rates
19. Faulty replication can sting
20. A new mitotic activity comes into focus
21. Correction: Publisher correction: The essential kinase ATR: ensuring faithful duplication of a challenging genome.
22. The essential kinase ATR: ensuring faithful duplication of a challenging genome
23. Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses
24. DNA Replication Modulates R-loop Levels to Maintain Genome Stability
25. Faculty Opinions recommendation of Activation of the ATR kinase by the RPA-binding protein ETAA1.
26. Faculty Opinions recommendation of ETAA1 acts at stalled replication forks to maintain genome integrity.
27. Conflict Resolution in the Genome: How Transcription and Replication Make It Work
28. Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells
29. Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage
30. Author response: Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage
31. Faculty Opinions recommendation of Replication stress activates DNA repair synthesis in mitosis.
32. Breaking bad: R-loops and genome integrity
33. DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome
34. Faculty Opinions recommendation of ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.
35. HLTF’s Ancient HIRAN Domain Binds 3′ DNA Ends to Drive Replication Fork Reversal
36. Transcription-Coupled Nucleotide Excision Repair Factors Promote R-Loop-Induced Genome Instability
37. Abstract 19299: PPARγ Plays a Novel, Pivotal Role in DNA Damage Sensing and Repair, That is Perturbed in Pulmonary Arterial Hypertension
38. Faculty Opinions recommendation of R-loops induce repressive chromatin marks over mammalian gene terminators.
39. DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis
40. The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability
41. Whole-Exome Sequencing Reveals TopBP1 as a Novel Gene in Idiopathic Pulmonary Arterial Hypertension
42. Faculty Opinions recommendation of PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.
43. Causes and consequences of replication stress
44. Faculty Opinions recommendation of FANCD2 binds MCM proteins and controls replisome function upon activation of s phase checkpoint signaling.
45. PHD domain from human SHPRH
46. NEK8 Links the ATR-Regulated Replication Stress Response and S Phase CDK Activity to Renal Ciliopathies
47. ATR phosphorylates SMARCAL1 to prevent replication fork collapse
48. A Role for the MRN Complex in ATR Activation via TOPBP1 Recruitment
49. Faculty Opinions recommendation of Identification of early replicating fragile sites that contribute to genome instability.
50. Faculty Opinions recommendation of The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends.
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