160 results on '"Deshaies, Raymond J."'
Search Results
2. The fatty liver disease-causing protein PNPLA3-I148M alters lipid droplet-Golgi dynamics
3. Assembly and Regulation of CRL Ubiquitin Ligases
4. Adaptive exchange sustains cullin–RING ubiquitin ligase networks and proper licensing of DNA replication
5. Targeted protein degradation: from small molecules to complex organelles—a Keystone Symposia report
6. A Systematic Interrogation of MHC Class I Peptide Presentation Identifies Constitutive and Compensatory Protein Degradation Pathways
7. In-depth proteomic analysis of proteasome inhibitors bortezomib, carfilzomib and MG132 reveals that mortality factor 4-like 1 (MORF4L1) protein ubiquitylation is negatively impacted
8. A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells
9. Control of Cullin-Ring Ubiquitin Ligase Activity by Nedd8
10. Inhibition of VCP preserves retinal structure and function in autosomal dominant retinal degeneration
11. Ubiquitin-dependent proteasomal degradation of AMPK gamma subunit by Cereblon inhibits AMPK activity
12. Multispecific drugs herald a new era of biopharmaceutical innovation
13. PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network
14. Transfer of ubiquitin protein caught in the act
15. Harnessing the Power of Proteolysis for Targeted Protein Inactivation
16. In Vitro Reconstitution of SCF Substrate Ubiquitination with Purified Proteins
17. Two‐Step Affinity Purification of Multiubiquitylated Proteins from Saccharomyces cerevisiae
18. Mapping phosphorylation sites in proteins by mass spectrometry
19. Cell Cycle Control by Ubiquitin-Dependent Proteolysis
20. Cell-free ubiquitination of cell cycle regulators in budding yeast extracts
21. Multisystem Proteinopathy Mutations in VCP/p97 Increase NPLOC4·UFD1L Binding and Substrate Processing
22. Single subunit degradation of WIZ, a lenalidomide- and pomalidomide-dependent substrate of E3 ubiquitin ligase CRL4CRBN
23. Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11
24. Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration
25. Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes
26. The pseudophosphatase STYX targets the F‐box of FBXW 7 and inhibitsSCF FBXW7 function
27. Cand1-Mediated Adaptive Exchange Mechanism Enables Variation in F-Box Protein Expression
28. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4
29. Structural Basis for the Inhibitory Effects of Ubistatins in the Ubiquitin-Proteasome Pathway
30. Composition and Regulation of the Cellular Repertoire of SCF Ubiquitin Ligases
31. Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy
32. Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases
33. Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L1 is enhanced by a mutation that causes multisystem proteinopathy
34. Correction to Discovery of an Inhibitor of the Proteasome Subunit Rpn11
35. p97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates
36. Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11
37. Discovery of an Inhibitor of the Proteasome Subunit Rpn11
38. The pseudophosphatase STYX targets the F‐box of FBXW 7 and inhibits SCF FBXW7 function
39. Valosin-containing protein (VCP)–Adaptor Interactions are Exceptionally Dynamic and Subject to Differential Modulation by a VCP Inhibitor
40. Nrf1 can be processed and activated in a proteasome-independent manner
41. Ribosomal proteins produced in excess are degraded by the ubiquitin–proteasome system
42. A conserved quality-control pathway that mediates degradation of unassembled ribosomal proteins
43. Author response: A conserved quality-control pathway that mediates degradation of unassembled ribosomal proteins
44. Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle
45. Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle
46. Author response: Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle
47. Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon
48. 2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition
49. Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway
50. Erratum: Corrigendum: Protein degradation: Prime time for PROTACs
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.