67 results on '"Goodyear, Richard"'
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2. Visualizing Collagen Fibrils in the Cochlea’s Tectorial and Basilar Membranes Using a Fluorescently Labeled Collagen-Binding Protein Fragment
3. Structure, Function, and Development of the Tectorial Membrane: An Extracellular Matrix Essential for Hearing
4. AAV-mediated rescue of Eps8 expression in vivo restores hair-cell function in a mouse model of recessive deafness
5. Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity
6. MET currents and otoacoustic emissions from mice with a detached tectorial membrane indicate the extracellular matrix regulates Ca 2+ near stereocilia
7. Age‐related changes in the biophysical and morphological characteristics of mouse cochlear outer hair cells
8. Ultrastructural defects in stereocilia and tectorial membrane in aging mouse and human cochleae
9. a-Tectorin
10. Accelerated Age-Related Degradation of the Tectorial Membrane in the Ceacam16βgal/βgal Null Mutant Mouse, a Model for Late-Onset Human Hereditary Deafness DFNB113
11. Spontaneous Otoacoustic Emissions in TectaY1870C/+ Mice Reflect Changes in Cochlear Amplification and How It Is Controlled by the Tectorial Membrane
12. Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death
13. Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning
14. A tectorin-based matrix and planar-cell-polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane
15. The acquisition of mechano‐electrical transducer current adaptation in auditory hair cells requires myosin VI
16. Increased Spontaneous Otoacoustic Emissions in Mice with a Detached Tectorial Membrane
17. Examining the role of the tectorial membrane in otoacoustic emission generation
18. The Development of Hair Cells in the Inner Ear
19. The CD 2 isoform of protocadherin‐15 is an essential component of the tip‐link complex in mature auditory hair cells
20. Staurosporine‐induced collapse of cochlear hair bundles
21. Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2
22. A mouse model for human deafness DFNB22 reveals that hearing impairment is due to a loss of inner hair cell stimulation
23. A Mutation in PNPT1, Encoding Mitochondrial-RNA-Import Protein PNPase, Causes Hereditary Hearing Loss
24. Mutations in Protocadherin 15 and Cadherin 23 Affect Tip Links and Mechanotransduction in Mammalian Sensory Hair Cells
25. Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia
26. Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with α-tectorin and is mutated in autosomal dominant hearing loss (DFNA4)
27. Evidence for multiple, developmentally regulated isoforms of Ptprq on hair cells of the inner ear
28. Otoancorin Knockout Mice Reveal Inertia is the Force for Hearing
29. Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane
30. Identification of the Hair Cell Soma-1 Antigen, HCS-1, as Otoferlin
31. Asymmetric distribution of cadherin 23 and protocadherin 15 in the kinocilial links of avian sensory hair cells
32. Actin-Bundling Protein TRIOBP Forms Resilient Rootlets of Hair Cell Stereocilia Essential for Hearing
33. In vivo and in vitro effects of two novel gamma-actin (ACTG1) mutations that cause DFNA20/26 hearing impairment
34. TRPML3 mutations cause impaired mechano‐electrical transduction and depolarization by an inward‐rectifier cation current in auditory hair cells of varitint‐waddler mice
35. Stereocilin-deficient mice reveal the origin of cochlear waveform distortions
36. Characterization of a Spontaneous, Recessive, Missense Mutation Arising in the Tecta Gene
37. A Mutation in CCDC50, a Gene Encoding an Effector of Epidermal Growth Factor–Mediated Cell Signaling, Causes Progressive Hearing Loss
38. Sharpened cochlear tuning in a mouse with a genetically modified tectorial membrane
39. Development of the hair bundle and mechanotransduction
40. TAp73 isoforms antagonize Notch signalling in SH‐SY5Y neuroblastomas and in primary neurones
41. The Tip-Link Antigen, a Protein Associated with the Transduction Complex of Sensory Hair Cells, Is Protocadherin-15
42. A deafness mutation isolates a second role for the tectorial membrane in hearing
43. Initial characterization of kinocilin, a protein of the hair cell kinocilium
44. Cadherin 23 is a component of the transient lateral links in the developing hair bundles of cochlear sensory cells
45. Development and properties of stereociliary link types in hair cells of the mouse cochlea
46. Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly
47. The Structure of Tip Links and Kinocilial Links in Avian Sensory Hair Bundles
48. The mechanical properties of chick (Gallus domesticus) sensory hair bundles: relative contributions of structures sensitive to calcium chelation and subtilisin treatment
49. Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase
50. An emilin family extracellular matrix protein identified in the cochlear basilar membrane
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