99 results on '"Johnson, Douglas S."'
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2. Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis
3. Utility of chemical probes for mass spectrometry based chemical proteomics
4. Contributors
5. Photobiomodulation therapy combined with static magnetic field is better than placebo in patients with fibromyalgia: a randomized placebo-controlled trial
6. γ-Secretase Modulators as Aβ42-Lowering Pharmacological Agents to Treat Alzheimer’s Disease
7. Low-intensity LASER and LED (photobiomodulation therapy) for pain control of the most common musculoskeletal conditions
8. COVID-19 Among US Dialysis Patients: Risk Factors and Outcomes From a National Dialysis Provider
9. Chemoproteomic Profiling of Covalent XPO1 Inhibitors to Assess Target Engagement and Selectivity
10. Photoaffinity Labeling and Quantitative Chemical Proteomics Identify LXRβ as the Functional Target of Enhancers of Astrocytic apoE
11. Chemical Proteomic Technologies for Drug Target Identification
12. Challenges with Providing Hospice Care for Patients Undergoing Long-Term Dialysis
13. The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease
14. Fluorophosphonate‐Based Degrader Identifies Degradable Serine Hydrolases by Quantitative Proteomics
15. Photoaffinity Labeling and Quantitative Chemical Proteomics Identify Liver X Receptor β as the Functional Target of Enhancers of Astrocytic Apolipoprotein E
16. Contemporary Drug Synthesis
17. Studies on the stability and stabilization of trans-cyclooctenes through radical inhibition and silver (I) metal complexation
18. PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor
19. Global Portrait of Protein Targets of Metabolites of the Neurotoxic Compound BIA 10–2474
20. Integrated Care for People with Kidney Disease
21. Leading Integrated Kidney Care Entities of the Future
22. Delaying and Averting Dialysis Treatment: Patient Protection or Moral Hazard?
23. Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation
24. Photochemical syntheses, transformations, and bioorthogonal chemistry oftrans-cycloheptene and silatrans-cycloheptene Ag(i) complexes
25. Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase
26. Bond with Me If You Can! Natural Product, Covalent Ligand, and Reactivity-Based Probe Compete for Cysteine in PP2A Complex
27. Structural and Chemical Biology of Presenilin Complexes
28. Discovery of cyclopropyl chromane-derived pyridopyrazine-1,6-dione γ-secretase modulators with robust central efficacy
29. Mapping the Binding Site of BMS-708163 on γ-Secretase with Cleavable Photoprobes
30. Photobiomodulation Therapy Improves Performance and Accelerates Recovery of High-Level Rugby Players in Field Test: A Randomized, Crossover, Double-Blind, Placebo-Controlled Clinical Study
31. Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors
32. Development of Sulfonamide Photoaffinity Inhibitors for Probing Cellular γ-Secretase
33. Going Upstream: Coordination to ImproveCKDCare
34. Nutrition, vitamin D, and health outcomes in hemodialysis
35. Preface
36. Recent developments and applications of clickable photoprobes in medicinal chemistry and chemical biology
37. Systematic Evaluation of Bioorthogonal Reactions in Live Cells with Clickable HaloTag Ligands: Implications for Intracellular Imaging
38. Blocking of Fatty Acid Amide Hydrolase Activity with PF-04457845 in Human Brain: A Positron Emission Tomography Study with the Novel Radioligand [11C]CURB
39. Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability
40. Infection Prevention and the Medical Director: Uncharted Territory
41. Discovery of indole-derived pyridopyrazine-1,6-dione γ-secretase modulators that target presenilin
42. A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS
43. Neuraminidase Inhibitors for Influenza: Oseltamivir Phosphate (Tamiflu®) and Zanamivir (Relenza®)
44. Chemoproteomics Demonstrates Target Engagement and Exquisite Selectivity of the Clinical Phosphodiesterase 10A Inhibitor MP-10 in Its Native Environment
45. Molecular medicine and neurodegenerative diseases
46. Oral Intradialytic Nutritional Supplement Use and Mortality in Hemodialysis Patients
47. Design, Synthesis, and Pharmacological Evaluation of a Novel Series of Pyridopyrazine-1,6-dione γ-Secretase Modulators
48. Investigating γ-secretase protein interactions in live cells using active site-directed clickable dual-photoaffinity probes
49. Development of CBAP-BPyne, a probe for γ-secretase and presenilinase
50. Discovery of selective 2,4-diaminopyrimidine-based photoaffinity probes for glyoxalase I
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