104 results on '"Kireev, Dmitri"'
Search Results
2. Efforts toward discovering inhibitors of the SYK SH2–FCER1γ interaction as potential Alzheimer’s disease chemical probes and therapeutics
3. Machine Learning-driven Fragment-based Discovery of CIB1-directed Anti-Tumor Agents by FRASE-bot
4. Supplementary Figure 3 from UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo
5. Supplementary Figure 2 from UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo
6. Supplementary Figure 4 from UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo
7. Supplementary Figure 1 from UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo
8. Supplementary Figure 3 from UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo
9. Data from UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo
10. Supplementary Figure 4 from UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo
11. Supplementary Figure 1 from UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo
12. Supplementary Figure 5 from UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo
13. Data from UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo
14. Supplementary Figure 2 from UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo
15. Supplementary Figure 5 from UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo
16. Relationship between lysine methyltransferase levels and heterochromatin gene repression in living cells and in silico
17. PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components
18. Structural basis of paralog-specific KDM2A/B nucleosome recognition
19. Dynamics of heterochromatin formation at submolecular resolution
20. Combining pharmacophore models derived from DNA-encoded chemical libraries with structure-based exploration to predict Tankyrase 1 inhibitors
21. Development of a high-throughput TR-FRET screening assay for a fast-cycling KRAS mutant
22. Enzymatic Macrolactamization of mRNA Display Libraries for Inhibitor Selection
23. MERTK activation drives osimertinib resistance in EGFR-mutant non–small cell lung cancer
24. A simulation model of heterochromatin formation at submolecular detail
25. Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity
26. Reprogramming CBX8-PRC1 function with a positive allosteric modulator
27. List of Contributors
28. Structure-Based Virtual Screening of Commercially Available Compound Libraries
29. Computational Chemical Biology of Methyllysine Histone Effectors
30. Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology
31. AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery
32. Combining Pharmacophore Models Derived from DNA-Encoded Chemical Libraries with Structure-Based Exploration to Predict Tankyrase 1 Inhibitors
33. Generation of the AD Informer Set: Chemical tools to facilitate Alzheimer’s disease drug discovery
34. A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization
35. Discovery and Development of Cyclic Peptide Inhibitors of CIB1
36. UNC5293, a potent, orally available and highly MERTK-selective inhibitor
37. AD Informer Set: Chemical tools to facilitate Alzheimer’s disease drug discovery
38. Correction to “A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes”
39. Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization
40. REPROGRAMMING CBX8-PRC1 FUNCTION WITH A POSITIVE ALLOSTERIC MODULATOR
41. Integrating DNA-encoded chemical libraries with virtual combinatorial library screening: Optimizing a PARP10 inhibitor
42. AI-driven 3D design for orphan targets from big PDB/SAR data
43. AI-driven 3D design for orphan targets from big PDB/SAR data
44. Design and Construction of a Focused DNA-Encoded Library for Multivalent Chromatin Reader Proteins
45. Off-Pocket Activity Cliffs: A Puzzling Facet of Molecular Recognition
46. Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7
47. Data-Driven Construction of Antitumor Agents with Controlled Polypharmacology
48. Dynamics of Substrate Processing by PPIP5K2, a Versatile Catalytic Machine
49. Discovery of selective activators of PRC2 mutant EED-I363M
50. Synthesis and Antibacterial Evaluation of Cephalosporin Isosteres
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