227 results on '"Kirk, Christopher"'
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2. 522 Quantitative proteomic profiling of KZR-540, a novel small molecule oral Sec61 inhibitor that selectively inhibits PD-1 expression
3. A 5-Year Analysis of Age, Stature and Armspan in Mixed Martial Arts
4. Pilot Pupillometry Data Examining The Effects Of Mixed Martial Arts Sparring On Autonomic Brain Function
5. Signal peptide mimicry primes Sec61 for client-selective inhibition
6. Combat Sports as a Model for Measuring the Effects of Repeated Head Impacts on Autonomic Brain Function: A Brief Report of Pilot Data
7. Development of subunit selective substrates forTrichomonas vaginalisproteasome
8. Supplementary Figures 1 - 7 from Carfilzomib and ONX 0912 Inhibit Cell Survival and Tumor Growth of Head and Neck Cancer and Their Activities Are Enhanced by Suppression of Mcl-1 or Autophagy
9. Supplementary Data from Nonproteasomal Targets of the Proteasome Inhibitors Bortezomib and Carfilzomib: a Link to Clinical Adverse Events
10. Supplementary Data from Nonproteasomal Targets of the Proteasome Inhibitors Bortezomib and Carfilzomib: a Link to Clinical Adverse Events
11. Supplementary Figure Legend from Carfilzomib and ONX 0912 Inhibit Cell Survival and Tumor Growth of Head and Neck Cancer and Their Activities Are Enhanced by Suppression of Mcl-1 or Autophagy
12. Supplementary Figure Legend from Carfilzomib and ONX 0912 Inhibit Cell Survival and Tumor Growth of Head and Neck Cancer and Their Activities Are Enhanced by Suppression of Mcl-1 or Autophagy
13. Supplementary Figures 1 - 7 from Carfilzomib and ONX 0912 Inhibit Cell Survival and Tumor Growth of Head and Neck Cancer and Their Activities Are Enhanced by Suppression of Mcl-1 or Autophagy
14. Supplementary Figure 2 from Antitumor Activity of PR-171, a Novel Irreversible Inhibitor of the Proteasome
15. Data from Antitumor Activity of PR-171, a Novel Irreversible Inhibitor of the Proteasome
16. Supplementary Figure 2 from Antitumor Activity of PR-171, a Novel Irreversible Inhibitor of the Proteasome
17. Supplementary Figure 1 from Antitumor Activity of PR-171, a Novel Irreversible Inhibitor of the Proteasome
18. Data from Antitumor Activity of PR-171, a Novel Irreversible Inhibitor of the Proteasome
19. Supplementary Figure 1 from Antitumor Activity of PR-171, a Novel Irreversible Inhibitor of the Proteasome
20. Zetomipzomib (KZR-616) attenuates lupus in mice via modulation of innate and adaptive immune responses
21. Rapid Weight Gain and Weight Differential Predict Competitive Success in 2100 Professional Combat-Sport Athletes
22. Intra-unit reliability and movement variability of submission grappling external load as measured by torso mounted accelerometery
23. The Relationships Between External and Internal Training Loads in Mixed Martial Arts
24. Position before submission? Techniques and tactics in competitive no-gi Brazilian jiu-jitsu
25. Co-inhibition of immunoproteasome subunits LMP2 and LMP7 enables prevention of transplant arteriosclerosis
26. Impact of Immunoproteasome Inhibition in Preclinical Studies of Hemophagocytic Lymphohistiocytosis
27. 422 KZR-540 is a novel oral small molecule inhibitor of Sec61 cotranslational translocation that potently and selectively blocks PD-1 expression
28. Effective therapy of polymyositis in mice via selective inhibition of the immunoproteasome
29. Signal peptide mimicry primes Sec61 for client-selective inhibition
30. Abstract 5592: Sec61 inhibitor KZR-834, an anti-cancer agent, exhibits immunomodulatory activity and combines with PD-1 blockade to further enhance immune responses
31. Inhibition of the Sec61 translocon overcomes cytokine‐induced glucocorticoid resistance in T‐cell acute lymphoblastic leukaemia
32. 3112 – IMPACT OF IMMUNOPROTEASOME INHIBITION IN MOUSE MODEL OF HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
33. Discovery and Early Clinical Development of Selective Immunoproteasome Inhibitors
34. Proteasome Inhibitors and Their Pharmacokinetics, Pharmacodynamics, and Metabolism
35. Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
36. Abstract 323: Quantitative proteomic profiling of novel anti-cancer small molecule inhibitors of Sec61: Mechanistic investigation and biomarker discovery
37. Abstract 2226: Prioritizing tumor types for clinical study of novel Sec61 inhibitors by searching for expression profiles of sensitive cell lines in tumor sample databases
38. Assessment of Cytokine-Modulated Proteasome Activity
39. Quantification of training load distribution in mixed martial arts athletes: A lack of periodisation and load management
40. Pre-competition body mass loss characteristics of Brazilian jiu-jitsu competitors in the United Kingdom
41. 207 Small molecule inhibitors of Sec61 cotranslational translocation regulate the phagocytosis checkpoint molecule CD47
42. Worth the Weight? Post Weigh-In Rapid Weight Gain is Not Related to Winning or Losing in Professional Mixed Martial Arts
43. The physical demands of mixed martial arts: A narrative review using the ARMSS model to provide a hierarchy of evidence
44. Preclinical evaluation of KZR-261, a novel small molecule inhibitor of Sec61.
45. P130 Treatment of SLE with the immunoproteasome inhibitor KZR-616: results from the first 4 cohorts of the MISSION study, an open-label phase 1b dose escalation trial
46. Effects of High-Intensity Interval Training in Combat Sports: A Systematic Review with Meta-Analysis
47. The pacing of mixed martial arts sparring bouts: A secondary investigation with new analyses of previous data to support accelerometry as a potential method of monitoring pacing
48. Blocking Protein Secretion with Novel Small Molecule Inhibitors of Sec61 Represents a Potential Treatment Strategy Against Hematologic Malignancies
49. Proteomic Profiling and Mechanistic Investigating of a Novel Anti-Cancer Small Molecule Inhibitor of Sec61
50. Protein Translocation Inhibitors Overcome Cytokine-Induced Glucocorticoid Resistance in T-Cell Acute Lymphoblastic Leukemia
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