43 results on '"Kostrewa, Dirk"'
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2. Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State
3. DNA Binding and Bending by two different Proteins: Factor for Inversion Stimulation (FIS) and Tetracycline Repressor (TetR)
4. Structural basis for ATP-dependent chromatin remodelling by the INO80 complex
5. cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders
6. Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly
7. An alternative RNA polymerase I structure reveals a dimer hinge
8. RNA polymerase I structure and transcription regulation
9. Design, Synthesis, and Biological and Crystallographic Evaluation of Novel Inhibitors of Plasmodium falciparum Enoyl-ACP-reductase (PfFabI)
10. Dynamic Architecture of a Minimal RNA Polymerase II Open Promoter Complex
11. Allosteric antibody inhibition of human hepsin protease
12. Dynamic Architecture of the RNA Polymerase II Open Promoter Complex
13. Crystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation
14. Evolution of Two Modes of Intrinsic RNA Polymerase Transcript Cleavage
15. Of Bits and Bugs — On the Use of Bioinformatics and a Bacterial Crystal Structure to Solve a Eukaryotic Repeat-Protein Structure
16. RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex
17. RNA polymerase II–TFIIB structure and mechanism of transcription initiation
18. The crystal structure of PfFabZ, the unique β-hydroxyacyl-ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum
19. Human OLA1 Defines an ATPase Subfamily in the Obg Family of GTP-binding Proteins
20. Crystal Structure of the Orf Virus NZ2 Variant of Vascular Endothelial Growth Factor-E
21. High-resolution Crystal Structure of AKR11C1 from Bacillus halodurans: An NADPH-dependent 4-Hydroxy-2,3-trans-nonenal Reductase
22. A conserved trimerization motif controls the topology of short coiled coils
23. Structural insights into the EB1–APC interaction
24. A DNA Glycosylase from Pyrobaculum aerophilum with an 8-Oxoguanine Binding Mode and a Noncanonical Helix-Hairpin-Helix Structure
25. Structural insights into the EB1?APC interaction
26. The mechanism of ammonia transport based on the crystal structure of AmtB of Escherichia coli
27. Exploring amyloid formation by a de novo design
28. New Antibacterial Agents Derived from the DNA Gyrase Inhibitor Cyclothialidine
29. From the DNA Gyrase Inhibitor Cyclothialidine to a New Class of Antibacterial Agents
30. Engineering of Phytase for Improved Activity at Low pH
31. Crystal Structures of Streptococcus pneumoniaeN-Acetylglucosamine-1-phosphate Uridyltransferase, GlmU, in Apo Form at 2.33Å Resolution and in Complex with UDP-N-Acetylglucosamine and Mg2+ at 1.96Å Resolution
32. Novel Inhibitors of DNA Gyrase: 3D Structure Based Biased Needle Screening, Hit Validation by Biophysical Methods, and 3D Guided Optimization. A Promising Alternative to Random Screening
33. Active site residue 297 of Aspergillus niger phytase critically affects the catalytic properties
34. From DNA sequence to improved functionality: using protein sequence comparisons to rapidly design a thermostable consensus phytase
35. Crystal engineering: a case study using the 24 kDa fragment of the DNA gyrase B subunit from Escherichia coli
36. Crystal engineering: deletion mutagenesis of the 24 kDa fragment of the DNA gyrase B subunit from Staphylococcus aureus
37. Crystal structure of Aspergillus niger pH 2.5 acid phosphatase at 2.4 Å resolution
38. Structure and function of the dihydropteroate synthase from staphylococcus aureus
39. Crystal structure of phytase from Aspergillus ficuum at 2.5 Å resolution
40. Mg2+ Binding to the Active Site of EcoRV Endonuclease: A Crystallographic Study of Complexes with Substrate and Product DNA at 2-.ANG. Resolution
41. Crystal structure of the factor for inversion stimulation FIS at 2.0 Å resolution
42. Three-dimensional structure of the E. coli DMA-binding protein FIS
43. Crystal structure of guanosine-free ribonuclease T1, complexed with vanadate(V), suggests conformational change upon substrate binding
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