143 results on '"Kwekkeboom, Jaap"'
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2. GITR Ligation Improves Anti-PD1-Mediated Restoration of Human MMR-Proficient Colorectal Carcinoma Tumor-Derived T Cells
3. 883 MCLA-145, an anti CD137×PD-L1 bispecific antibody, induces T cell activation and proliferation in ex vivo models of hepatocellular carcinoma
4. 1181 Therapeutic vaccines consisting of cancer germline antigen-based synthetic long peptides are immunogenic in human hepatocellular carcinoma patients
5. Systemic T-cell and humoral responses against cancer testis antigens in hepatocellular carcinoma patients
6. Minimal Development of Liver Fibrosis in Adult Tolerant Liver Transplant Recipients Late After Immunosuppressive Drug Weaning and Transplantation
7. Modelling immune cytotoxicity for cholangiocarcinoma with tumour-derived organoids and effector T cells
8. Current Tolerance-Associated Peripheral Blood Gene Expression Profiles After Liver Transplantation Are Influenced by Immunosuppressive Drugs and Prior Cytomegalovirus Infection
9. Immune suppressive checkpoint interactions in the tumour microenvironment of primary liver cancers
10. An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity
11. TIGIT, the Next Step Towards Successful Combination Immune Checkpoint Therapy in Cancer
12. Activated CD4 + T Cells and Highly Differentiated Alloreactive CD4 + T Cells Distinguish Operationally Tolerant Liver Transplantation Recipients
13. Detection of oncogenic mutations in paired circulating tumor DNA and circulating tumor cells in patients with hepatocellular carcinoma
14. Expression of Cancer Testis Antigens in Tumor-Adjacent Normal Liver Is Associated with Post-Resection Recurrence of Hepatocellular Carcinoma
15. HLA matching and rabbit antithymocyte globulin as induction therapy to avoid multiple forms of rejection after a third liver transplantation
16. Cancer Cell B7-H3 Expression Is More Prevalent in the Pancreato-Biliary Subtype of Ampullary Cancer Than in Pancreatic Cancer
17. Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance
18. TIGIT and PD1 Co-blockade Restores ex vivo Functions of Human Tumor-Infiltrating CD8+ T Cells in Hepatocellular Carcinoma
19. Camrelizumab—targeting a novel PD-1 epitope to treat hepatocellular carcinoma
20. 588 Targeting GITR enhances human tumour-infiltrating T cell functionality in mismatch repair proficient primary colorectal carcinoma and liver metastases
21. The biological process of lysine‐tRNA charging is therapeutically targetable in liver cancer
22. Modulation of Dendritic Cells and Regulatory T Cells by Naturally Occurring Antibodies
23. FcγRIIB engagement drives agonistic activity of Fc-engineered αOX40 antibody to stimulate human tumor-infiltrating T cells
24. Modelling liver tumor organoids and cancer-associated fibroblasts interaction reveals the robust effects of stromal niche in cancer nurturing and treatment resistance
25. Identification of a panel of safe immunogenic antigens for therapeutic vaccination strategies in hepatocellular carcinoma
26. TIGIT and PD1 dual checkpoint blockade restores functionality of tumor-infiltrating T cells in hepatocellular carcinoma
27. Expression of Cancer testis Antigens in Tumor-adjacent Normal Liver Predicts Post-resection Recurrence of Hepatocellular Carcinoma
28. Enrichment of the tumour immune microenvironment in patients with desmoplastic colorectal liver metastasis
29. LGR5 marks targetable tumor-initiating cells in mouse liver cancer
30. HHLA2 is expressed in pancreatic and ampullary cancers and increased expression is associated with better post-surgical prognosis
31. Observed differences in the tumour microenvironment provide a potential explanation for the superior survival of patients with desmoplastic colorectal liver metastasis
32. Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth
33. Immunosuppressive drug withdrawal late after liver transplantation improves the lipid profile and reduces infections
34. Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules
35. Circulating levels of PD-L1 and Galectin-9 are associated with patient survival in surgically treated Hepatocellular Carcinoma independent of their intra-tumoral expression levels
36. Suppression of Hepatocellular Carcinoma by Mycophenolic Acid in Experimental Models and in Patients
37. Characterization of Antigen-Presenting Cell Subsets in Human Liver-Draining Lymph Nodes
38. GITR ligation enhances functionality of tumor‐infiltrating T cells in hepatocellular carcinoma
39. Dichotomal functions of phosphorylated and unphosphorylated STAT1 in hepatocellular carcinoma
40. Action and clinical significance of CCAAT/enhancer-binding protein delta in hepatocellular carcinoma
41. Modeling liver cancer and therapy responsiveness using organoids derived from primary mouse liver tumors
42. Prognostic value of intra-tumoral CD8+ /FoxP3+ lymphocyte ratio in patients with resected colorectal cancer liver metastasis
43. Blockade of LAG3 enhances responses of tumor-infiltrating T cells in mismatch repair-proficient liver metastases of colorectal cancer
44. Potential Beneficial Effects of Cytomegalovirus Infection after Transplantation
45. Donor-specific anti-HLA antibodies are not associated with nonanastomotic biliary strictures but both are independent risk factors for graft loss after liver transplantation
46. Addendum to “MicroRNA profiles in graft preservation solution are predictive of ischemic-type biliary lesions after liver transplantation” [J Hepatol 2013;59:1231–1238]
47. JAK-inhibitor tofacitinib suppresses interferon alfa production by plasmacytoid dendritic cells and inhibits arthrogenic and antiviral effects of interferon alfa
48. Dynamics of Proliferative and Quiescent Stem Cells in Liver Homeostasis and Injury
49. Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas
50. Cross-Tissue Transcriptomic Analysis of Human Secondary Lymphoid Organ-Residing ILC3s Reveals a Quiescent State in the Absence of Inflammation
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