89 results on '"L. Michel"'
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2. Mechanisms for cardiac SERCA activation by its substrate and a synthetic allosteric modulator using fluorescence lifetime imaging
3. Phospholamban Inhibits the Cardiac Calcium Pump Through Reversing the Allosteric Enhancement of Calcium Affinity by ATP
4. A novel machine learning-based screening identifies statins as inhibitors of the calcium pump SERCA
5. The mechanism of dwarf open reading frame (DWORF) activation of the sarcoplasmic reticulum calcium pump SERCA
6. Deep learning identification of cardiac transporters as targets for approved drugs
7. Sodium pump regulation in health and disease
8. Primitive Phospholamban- and Sarcolipin-like Peptides Inhibit the Sarcoplasmic Reticulum Calcium Pump SERCA
9. Fluorescence lifetime imaging microscopy reveals sodium pump dimers in live cells
10. Deep learning accelerates discovery of novel modulators targeting cardiac calcium transport
11. Stoichiometry of the sodium pump-phospholemman regulatory complex
12. A multiscale approach for bridging the gap between potency, efficacy, and safety of small molecules directed at membrane proteins
13. Dwarf open reading frame (DWORF) is a direct activator of the sarcoplasmic reticulum calcium pump SERCA
14. Author response: Dwarf open reading frame (DWORF) is a direct activator of the sarcoplasmic reticulum calcium pump SERCA
15. Structural Basis for the Function of the C-Terminal Proton Release Pathway in the Calcium Pump
16. From atoms to cells: bridging the gap between potency, efficacy, and safety of small molecules directed at a membrane protein
17. Dynamics-Driven Allostery Underlies Ca2+-Mediated Release of SERCA Inhibition by Phospholamban
18. Dwarf open reading frame (DWORF) peptide is a direct activator of the sarcoplasmic reticulum calcium pump SERCA
19. Atomistic Structure and Dynamics of the Ca2+-ATPase Bound to Phosphorylated Phospholamban
20. Multiscale Simulation Reveals Passive Proton Transport Through SERCA on the Microsecond Timescale
21. Sarcolambans are phospholamban- and sarcolipin-like regulators of the sarcoplasmic reticulum calcium pump SERCA
22. Conserved Luminal C-Terminal Domain Dynamically Controls Interdomain Communication in Sarcolipin
23. Multiscale Simulation Reveals Passive Proton Transport Through SERCA on the Microsecond Timescale
24. Linking Biochemical and Structural States of SERCA: Achievements, Challenges, and New Opportunities
25. Dynamics-driven allostery underlies pre-activation of the regulatory Ca2+-ATPase/phospholamban complex
26. Conserved luminal C-terminal domain dynamically controls interdomain communication in sarcolipin
27. Predicting the pKa Shift of Acidic Residues in the Calcium-Binding Sites of Serca using Alchemical Free-Energy Calculations
28. Interaction of a Sarcolipin Pentamer and Monomer with the Sarcoplasmic Reticulum Calcium Pump, SERCA
29. Interaction of a Sarcolipin Pentamer and Monomer with the Sarcoplasmic Reticulum Calcium Pump, SERCA
30. Horse gluteus is a null-sarcolipin muscle with enhanced sarcoplasmic reticulum calcium transport
31. Probing the effects of nonannular lipid binding on the stability of the calcium pump SERCA
32. The Phospholamban Pentamer Functionally Interacts with the Sarcoplasmic Reticulum Calcium Pump SERCA
33. The Phospholamban Pentamer Alters Function of the Sarcoplasmic Reticulum Calcium Pump SERCA
34. Structural Basis for the Limited Response to Oxidative and Thiol-Conjugating Agents by Triosephosphate Isomerase From the Photosynthetic Bacteria Synechocystis
35. Probing the effects of nonannular lipid binding on the stability of the calcium pump SERCA
36. Structural basis for relief of phospholamban-mediated inhibition of the sarcoplasmic reticulum Ca2+-ATPase at saturating Ca2+ conditions
37. Tuberculosis Infection: Occurrence and Risk Factors in Presumptive Tuberculosis Patients of the Serengeti Ecosystem in Tanzania
38. The Ca2+-ATPase pump facilitates bidirectional proton transport across the sarco/endoplasmic reticulum
39. Preexisting domain motions underlie protonation-dependent structural transitions of the P-type Ca2+-ATPase
40. Sarcolipin Promotes Uncoupling of the SERCA Ca2+ Pump by Inducing a Structural Rearrangement in the Energy-Transduction Domain
41. Site-directed spectroscopy of cardiac myosin-binding protein C reveals effects of phosphorylation on protein structural dynamics
42. Structural Measurements within the M-Domain Reveal Unique Details of Cardiac Myosin Binding Protein-C Phosphorylation
43. Atomistic Characterization of the First Step of Calcium Pump Activation Associated with Proton Countertransport
44. Sarcolipin and phospholamban inhibit the calcium pump by populating a similar metal ion-free intermediate state
45. Microsecond Molecular Simulations Reveal a Transient Proton Pathway in the Calcium Pump
46. Atomic-Level Mechanisms for Phospholamban Regulation of the Calcium Pump
47. Atomic-Level Characterization of the Inhibition Mechanism of the Calcium Pump by Phospholamban
48. Tarantula myosin free head regulatory light chain phosphorylation stiffens N-terminal extension, releasing it and blocking its docking back
49. Sequential myosin phosphorylation activates tarantula thick filament via a disorder–order transition
50. High-resolution structural characterization of Noxa, an intrinsically disordered protein, by microsecond molecular dynamics simulations
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