34 results on '"Lanyon-Hogg, Thomas"'
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2. Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase
3. Identification of the first structurally validated covalent ligands of the small GTPase RAB27A
4. Structure, mechanism, and inhibition of Hedgehog acyltransferase
5. Proteome-wide analysis of protein lipidation using chemical probes: in-gel fluorescence visualization, identification and quantification of N-myristoylation, N- and S-acylation, O-cholesterylation, S-farnesylation and S-geranylgeranylation
6. Structure and Mechanism of Hedgehog Acyl Transferase
7. Photochemical Probe Identification of a Small‐Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT)**
8. Photochemical Probe Identification of a Small‐Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT)**
9. Targeting the bacterial SOS response for new antimicrobial agents: drug targets, molecular mechanisms and inhibitors
10. Photochemical probe identification of the small-molecule binding site in a mammalian membrane-bound O-acyltransferase
11. Correction to “Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity”
12. Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity
13. Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Anti-Fibrotic Activity
14. Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Anti-Fibrotic Activity
15. Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus
16. Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics
17. Acylation-coupled lipophilic induction of polarisation (Acyl-cLIP): a universal assay for lipid transferase and hydrolase enzymes
18. Dynamic Protein Acylation: New Substrates, Mechanisms, and Drug Targets
19. Microfluidic Mobility Shift Assay for Real-Time Analysis of Peptide N-Palmitoylation
20. Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane
21. Direct Targeting of the Ras GTPase Superfamily Through Structure- Based Design
22. Characterization of Hedgehog Acyltransferase Inhibitors Identifies a Small Molecule Probe for Hedgehog Signaling by Cancer Cells
23. Correction: Peroxisome protein import: a complex journey
24. Synthesis and characterisation of 5-acyl-6,7-dihydrothieno[3,2-c]pyridine inhibitors of Hedgehog acyltransferase
25. Covalent Label Transfer between Peroxisomal Importomer Components Reveals Export-driven Import Interactions
26. Click chemistry armed enzyme-linked immunosorbent assay to measure palmitoylation by hedgehog acyltransferase
27. Modulation of Amide Bond Rotamers in 5-Acyl-6,7-dihydrothieno[3,2-c]pyridines
28. Membrane bound O-acyltransferases and their inhibitors
29. Topological Analysis of Hedgehog Acyltransferase, a Multipalmitoylated Transmembrane Protein
30. Global profiling of protein lipidation using chemical proteomic technologies
31. PEX14 binding to Arabidopsis PEX5 has differential effects on PTS1 and PTS2 cargo occupancy of the receptor
32. ChemInform Abstract: Synthesis of Small Molecules with High Scaffold Diversity: Exploitation of Metathesis Cascades in Combination with Inter‐ and Intramolecular Diels—Alder Reactions.
33. Synthesis of Small Molecules with High Scaffold Diversity: Exploitation of Metathesis Cascades in Combination with Inter- and Intramolecular Diels-Alder Reactions
34. Getting a camel through the eye of a needle: the import of folded proteins by peroxisomes
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