16 results on '"Papoian, Thomas"'
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2. Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes
3. Moving beyond the comprehensive in vitro proarrhythmia assay: Use of human-induced pluripotent stem cell-derived cardiomyocytes to assess contractile effects associated with drug-induced structural cardiotoxicity
4. Preclinical approaches to assess potential kinase inhibitor‐induced cardiac toxicity: Past, present and future
5. Induced Pluripotent Stem Cell-Derived Cardiomyocytes: An In Vitro Model to Predict Tyrosine Kinase Inhibitor (TKI)-Induced Structural Cardiotoxicity
6. Safety of antisense oligonucleotide and siRNA-based therapeutics
7. Regulatory Forum Review*: Utility of in Vitro Secondary Pharmacology Data to Assess Risk of Drug-induced Valvular Heart Disease in Humans: Regulatory Considerations
8. Effects of 31 FDA approved small-molecule kinase inhibitors on isolated rat liver mitochondria
9. Secondary pharmacology data to assess potential off-target activity of new drugs: a regulatory perspective
10. Tyrosine kinase inhibitor (TKI)-induced cardiotoxicity: approaches to narrow the gaps between preclinical safety evaluation and clinical outcome
11. Chemical Effects in Biological Systems—Data Dictionary (CEBS-DD): A Compendium of Terms for the Capture and Integration of Biological Study Design Description, Conventional Phenotypes, and ‘Omics Data
12. Genomics and Drug Toxicity
13. Selective alterations in rat cardiac mRNA induced by doxorubicin: Possible subcellular mechanisms
14. Absence of Down-Regulation of Insulin Receptors in Human Breast Cancer Cells (MCF-7) Cultured in Serum-Free Medium: Comparison with Epidermal Growth Factor
15. Ethanolamine mimics insulin effects invitro
16. Insulin-like activity of chromium-binding fractions from brewer's yeast
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