267 results on '"Whisstock, James C"'
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2. A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen
3. Fragment-based and structure-guided discovery of perforin inhibitors
4. A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen
5. A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen
6. The role of NINJ1 protein in programmed cellular destruction
7. OpenFIBSEM: A universal API for FIBSEM control
8. TcpA from the Clostridium perfringens plasmid pCW3 is more closely related to the DNA translocase FtsK than to coupling proteins
9. Front Cover: Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors (ChemMedChem 6/2023)
10. Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors
11. The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9
12. OpenFIBSEM: an application programming interface for easy FIB/SEM automation
13. Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor
14. Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism
15. The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9
16. Mpeg1 is not essential for antibacterial or antiviral immunity, but is implicated in antigen presentation
17. A mechanism for hereditary angioedema caused by a lysine 311–to–glutamic acid substitution in plasminogen
18. Protein engineering of a stable and potent anti-inflammatory IL-37-Fc fusion with enhanced therapeutic potential
19. Mining folded proteomes in the era of accurate structure prediction
20. Helical ultrastructure of the oncogenic metalloprotease meprin α in complex with a small molecule hydroxamate inhibitor
21. Macrophage self‐renewal is regulated by transient expression of PDGF‐ and VEGF‐related factor 2
22. The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1
23. Structural analysis of the PTEN:P-Rex2 signaling complex reveals how cancer-associated mutations coordinate to hyperactivate Rac1
24. The cryo-EM structure of the neurofibromin dimer reveals the molecular basis for von Recklinghausen disease
25. Oxygen Plasma Focused Ion Beam: Optimised Beam Chemistry to Improve the Throughput of FIB/SEM Tomography on Biological Samples
26. Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities
27. Ancient but Not Forgotten: New Insights Into MPEG1, a Macrophage Perforin-Like Immune Effector
28. Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface
29. Mapping the binding site of C1-inhibitor for polyanion cofactors
30. Crystallography of Serpins and Serpin Complexes
31. Preface
32. Predicting Serpin/Protease Interactions
33. Preface
34. Bioinformatics of Protein Function
35. Drosophilamacrophage self-renewal is regulated by transient expression of PDGF- and VEGF-related factor 2
36. Automated cryo-lamella preparation for high-throughput in-situ structural biology
37. Structural analysis of the PTEN:P-Rex2 signalling node reveals how cancer-associated mutations coordinate to hyperactivate Rac1
38. Parsing the IL-37-Mediated Suppression of Inflammasome Function
39. Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma
40. Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer
41. MENT, a Chromatin-Associated Serpin from Avian Blood Cells: Structure and Function
42. Evolution and Classification of the Serpin Superfamily
43. Serpins in Prokaryotes
44. Automated cryo-lamella preparation for high-throughput in-situ structural biology
45. Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes
46. Serpins
47. The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1
48. Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding
49. PIE-scope, integrated cryo-correlative light and FIB/SEM microscopy
50. Control of growth factor signalling by MACPF proteins
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