1. Damage to dorsolateral prefrontal cortex affects tradeoffs between honesty and self-interest
- Author
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Zhu, Lusha, Jenkins, Adrianna C, Set, Eric, Scabini, Donatella, Knight, Robert T, Chiu, Pearl H, King-Casas, Brooks, and Hsu, Ming
- Subjects
Biological Psychology ,Psychology ,Basic Behavioral and Social Science ,Behavioral and Social Science ,Brain Injuries ,Brain Mapping ,Choice Behavior ,Cohort Studies ,Female ,Games ,Experimental ,Humans ,Image Processing ,Computer-Assisted ,Male ,Models ,Neurological ,Morals ,Motivation ,Prefrontal Cortex ,Statistics ,Nonparametric ,Neurosciences ,Cognitive Sciences ,Neurology & Neurosurgery ,Biological psychology - Abstract
Substantial correlational evidence suggests that prefrontal regions are critical to honest and dishonest behavior, but causal evidence specifying the nature of this involvement remains absent. We found that lesions of the human dorsolateral prefrontal cortex (DLPFC) decreased the effect of honesty concerns on behavior in economic games that pit honesty motives against self-interest, but did not affect decisions when honesty concerns were absent. These results point to a causal role for DLPFC in honest behavior.
- Published
- 2014