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Exoplanet science is one of the most thriving fields of modern astrophysics. A major goal is the atmospheric characterization of dozens of small, terrestrial exoplanets in order to search for signatures in their atmospheres that indicate biological activity, assess their ability to provide conditions for life as we know it, and investigate their expected atmospheric diversity. None of the currently adopted projects or missions, from ground or in space, can address these goals. In this White Paper, submitted to ESA in response to the Voyage 2050 Call, we argue that a large space-based mission designed to detect and investigate thermal emission spectra of terrestrial exoplanets in the mid-infrared wavelength range provides unique scientific potential to address these goals and surpasses the capabilities of other approaches. While NASA might be focusing on large missions that aim to detect terrestrial planets in reflected light, ESA has the opportunity to take leadership and spearhead the development of a large mid-infrared exoplanet mission within the scope of the "Voyage 2050" long-term plan establishing Europe at the forefront of exoplanet science for decades to come. Given the ambitious science goals of such a mission, additional international partners might be interested in participating and contributing to a roadmap that, in the long run, leads to a successful implementation. A new, dedicated development program funded by ESA to help reduce development and implementation cost and further push some of the required key technologies would be a first important step in this direction. Ultimately, a large mid-infrared exoplanet imaging mission will be needed to help answer one of humankind's most fundamental questions: "How unique is our Earth?"

We present the most sensitive direct imaging and radial velocity (RV) exploration of Eridani to date. Eridani is an adolescent planetary system, reminiscent of the early solar system. It is surrounded by a prominent and complex debris disk that is likely stirred by one or several gas giant exoplanets. The discovery of the RV signature of a giant exoplanet was announced 15 yr ago, but has met with scrutiny due to possible confusion with stellar noise. We confirm the planet with a new compilation and analysis of precise RV data spanning 30 yr, and combine it with upper limits from our direct imaging search, the most sensitive ever performed. The deep images were taken in the Ms band (4.7 μm) with the vortex coronagraph recently installed in W.M. Keck Observatory's infrared camera NIRC2, which opens a sensitive window for planet searches around nearby adolescent systems. The RV data and direct imaging upper limit maps were combined in an innovative joint Bayesian analysis, providing new constraints on the mass and orbital parameters of the elusive planet. Eridani b has a mass of M Jup and is orbiting Eridani at about 3.48 ± 0.02 au with a period of 7.37 ± 0.07 yr. The eccentricity of Eridani b's orbit is an order of magnitude smaller than early estimates and consistent with a circular orbit. We discuss our findings from the standpoint of planet-disk interactions and prospects for future detection and characterization with the James Webb Space Telescope.

The prime Kepler mission revealed that small planets (