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1. Infection with Kaposi's sarcoma-associated herpesvirus (KSHV) and human immunodeficiency virus (HIV) in relation to the risk and clinical presentation of Kaposi's sarcoma in Uganda

Author

Newton, R, Ziegler, J, Bourboulia, D, Casabonne, D, Beral, V, Mbidde, E, Carpenter, L, Parkin, DM, Wabinga, H, Mbulaiteye, S, Jaffe, H, Weiss, R, and Boshoff, C

Subjects
Cancer, HIV/AIDS, Emerging Infectious Diseases, Rare Diseases, Infectious Diseases, Pediatric, Aetiology, 2.1 Biological and endogenous factors, Infection, Adolescent, Adult, Antibodies, Viral, Case-Control Studies, Female, HIV Infections, Herpesvirus 8, Human, Humans, Male, Risk Factors, Sarcoma, Kaposi, Seroepidemiologic Studies, Severity of Illness Index, Uganda, Oncology and Carcinogenesis, Public Health and Health Services, Oncology & Carcinogenesis
Abstract

A case-control study from Uganda found that the risk of Kaposi's sarcoma increased with increasing titre of antibodies against Kaposi's sarcoma-associated herpesvirus (KSHV) latent nuclear antigens, independently of HIV infection. Clinically, widespread Kaposi's sarcoma was more frequent among patients with HIV infection than in those without, but was not related to anti-KSHV antibody titres.

Published
2003

2. Infection with Kaposi's sarcoma-associated herpesvirus (KSHV) and human immunodeficiency virus (HIV) in relation to the risk and clinical presentation of Kaposi's sarcoma in Uganda.

Author

Newton, R, Ziegler, J, Bourboulia, D, Casabonne, D, Beral, V, Mbidde, E, Carpenter, L, Parkin, DM, Wabinga, H, Mbulaiteye, S, Jaffe, H, Weiss, R, and Boshoff, C

Subjects
Humans, Herpesvirus 8, Human, Sarcoma, Kaposi, HIV Infections, Antibodies, Viral, Severity of Illness Index, Risk Factors, Case-Control Studies, Seroepidemiologic Studies, Adolescent, Adult, Uganda, Female, Male, Antibodies, Viral, Herpesvirus 8, Human, Sarcoma, Kaposi, Oncology and Carcinogenesis, Public Health and Health Services, Oncology & Carcinogenesis
Abstract

A case-control study from Uganda found that the risk of Kaposi's sarcoma increased with increasing titre of antibodies against Kaposi's sarcoma-associated herpesvirus (KSHV) latent nuclear antigens, independently of HIV infection. Clinically, widespread Kaposi's sarcoma was more frequent among patients with HIV infection than in those without, but was not related to anti-KSHV antibody titres.

Published
2003

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