Ebekozien, Osagie, Agarwal, Shivani, Noor, Nudrat, Albanese-O'Neill, Anastasia, Wong, Jenise C, Seeherunvong, Tossaporn, Sanchez, Janine, DeSalvo, Daniel, Lyons, Sarah K, Majidi, Shideh, Wood, Jamie R, Acharya, Runa, Aleppo, Grazia, Sumpter, Kathryn M, Cymbaluk, Anna, Shah, Nirali A, Van Name, Michelle, Cruz-Aviles, Lisa, Alonso, Guy Todd, Gallagher, Mary Pat, Sanda, Srinath, Feuer, Alexis Jamie, Cossen, Kristina, Rioles, Nicole, Jones, Nana-Hawa Yayah, Kamboj, Manmohan K, and Hirsch, Irl B
ObjectiveWe examined whether diabetic ketoacidosis (DKA), a serious complication of type 1 diabetes (T1D) was more prevalent among Non-Hispanic (NH) Black and Hispanic patients with T1D and laboratory-confirmed coronavirus disease 2019 (COVID-19) compared with NH Whites.MethodThis is a cross-sectional study of patients with T1D and laboratory-confirmed COVID-19 from 52 clinical sites in the United States, data were collected from April to August 2020. We examined the distribution of patient factors and DKA events across NH White, NH Black, and Hispanic race/ethnicity groups. Multivariable logistic regression analysis was performed to examine the odds of DKA among NH Black and Hispanic patients with T1D as compared with NH White patients, adjusting for potential confounders, such as age, sex, insurance, and last glycated hemoglobin A1c (HbA1c) level.ResultsWe included 180 patients with T1D and laboratory-confirmed COVID-19 in the analysis. Forty-four percent (n = 79) were NH White, 31% (n = 55) NH Black, 26% (n = 46) Hispanic. NH Blacks and Hispanics had higher median HbA1c than Whites (%-points [IQR]: 11.7 [4.7], P