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Since adult measles have been found，and outbreaks of measles have sometimes occurred in Japan in re-cent years，so twice vaccinations have been pointed out to be needed to take since 2006. Those who have no or once vaccination received for young generation should take twice of MR vaccine at age of 13 years old and at age of 17 old from 2008 to 2013. Unfortunately，ratio of MR vaccine taking is not so high，so out-breaks of Measles will be apprehensive to be occurring.

Gastroesophageal reflux（GER）with sliding hernia can cause chronic cough or bronchial asthma. In late years，these reports of pulmonary disease with GERD（gastroesophageal reflux disease）are increasing in Asia. We experienced older aged woman with bronchial athma complicated with GERD. However increasing reports of asthma with GERD，the cause of brobchoconstriction complicated with sliding hernia is stil unclear. Previous researchers found a significantly higher incidence rate for GERD in those with a previous diagnosis of asthma than in controls，indicating that patients with asthma were 1.8 times more likely to evelop GERD than those without asthma. In this study，we reviewed the association between gastro-esophageal reflux disease and sthma.