Search

Introduction: REM rebound is defined as an increase of ≥ 20% of REM sleep during the first exposure to CPAP therapy, compared to the diagnostic night, with the presence of at least 1 REM episode of ≥ 30 min.1 The aim of this study was to describe the prevalence of REM rebound (during CPAP titration), the characteristics of these patients, and the correlation with CPAP compliance. Methods: 665 OSA patients were studied (baseline AHI > 20). Subjects underwent polysomnography (PSG) during both the diagnostic and CPAP titration night. CPAP compliance (minimal use for ≥ 3 hours a night) was assessed at 1 M, at 1 Y, and at 2 Y follow-up. Results: 34 Subjects presented with REM rebound during CPAP titration (prevalence of 5%). Those with REM rebound were more obese, had less REM sleep, a longer REM latency, and a higher AHI. These patients used CPAP significantly more during the first M of follow-up. However, this effect disappeared on the long-term. Conclusions: REM rebound has a rather low prevalence in OSA patients during CPAP titration. These patients are more obese and demonstrate more impairment of their sleep architecture at baseline conditions. Presence of REM rebound on initial CPAP exposure is associated with a higher short-term CPAP compliance. Reference Brillante, R., et al. Respirology 2012,17:547-53.