1. Diagnostic performances of FDG-PET/CT and diffusion-weighted imaging indices for differentiating benign pheochromocytoma from other benign adrenal tumors
- Author
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Takashi Yoshiura, Yoshihiko Fukukura, Kiyohisa Kamimura, Masayuki Nakajo, Toshikazu Shindo, Tomohide Yoneyama, Yoshiaki Nakabeppu, Koji Takumi, Masatoyo Nakajo, and Megumi Jinguji
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,Urology ,Adrenal Gland Neoplasms ,Standardized uptake value ,Pheochromocytoma ,Multimodal Imaging ,Sensitivity and Specificity ,Diagnosis, Differential ,Young Adult ,Fluorodeoxyglucose F18 ,Adrenal Glands ,medicine ,Humans ,Effective diffusion coefficient ,Radiology, Nuclear Medicine and imaging ,Benign adrenal tumors ,Aged ,Aged, 80 and over ,Radiological and Ultrasound Technology ,Receiver operating characteristic ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,Area under the curve ,Reproducibility of Results ,General Medicine ,Middle Aged ,medicine.disease ,body regions ,Diffusion Magnetic Resonance Imaging ,Positron emission tomography ,Positron-Emission Tomography ,Mann–Whitney U test ,Female ,Radiology ,Radiopharmaceuticals ,Tomography, X-Ray Computed ,business - Abstract
Purpose: The purpose of this study is to compare diagnostic performances of 18F-fluorodeoxyglucose (FDG) visual score, maximum standardized uptake value (SUVmax), ratio of adrenal SUVmax to liver SUVmax (A/L SUVmax), apparent diffusion coefficient (ADC) from diffusion-weighted imaging, and SUVmax/ADC ratio to differentiate adrenal pheochromocytoma from other benign tumors. Methods: Eleven pheochromocytomas and 22 other benign tumors in 30 patients were included. FDG-based indices, ADC, and SUVmax/ADC ratio were compared between groups using the Mann–Whitney U test, and sensitivity, specificity, accuracy, and area under the curve (AUC) for diagnosing pheochromocytoma by receiver operating characteristic analyses. The correlation between SUVmax and ADC was analyzed using the Spearman’s rank test. Results: Pheochromocytoma showed significantly higher visual score (2.8 ± 0.4 vs. 1.3 ± 0.9), SUVmax (11.0 ± 8.9 vs. 3.2 ± 1.4), A/L SUVmax ratio (3.96 ± 3.48 vs. 0.96 ± 0.51), and SUVmax/ADC ratio (10.6 ± 8.09 vs. 2.28 ± 0.98) (each P
- Published
- 2014