14 results on '"pancreatic carcinoma"'
Search Results
2. Recurrent pancreatic carcinoma and cholangiocarcinoma: 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT).
- Author
-
Cameron, Katherine, Golan, Sivan, Simpson, William, Peti, Steven, Roayaie, Sasan, Labow, Daniel, and Kostakoglu, Lale
- Subjects
- *
PANCREATIC cancer , *CHOLANGIOCARCINOMA , *FLUOROSIS , *GLUCOSE , *POSITRON emission tomography , *CANCER relapse - Abstract
Although the current literature is limited, available data suggest that (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) imaging improves the evaluation of patients with recurrent pancreatic carcinoma and cholangiocarcinoma. There is evidence that PET/CT is particularly useful in the setting of elevated tumor markers and negative or equivocal CT findings. This article reviews the nature of these carcinomas in the post-therapy setting and describes the strengths and limitations of PET/CT when used for monitoring recurrence. [ABSTRACT FROM AUTHOR]
- Published
- 2011
- Full Text
- View/download PDF
3. Peripancreatic lymphatic invasion by pancreatic carcinoma: evaluation with multi-detector row CT.
- Author
-
Sai, Michiaki, Mori, Hiromu, Kiyonaga, Maki, Kosen, Kazuhisa, Yamada, Yasunari, and Matsumoto, Shunro
- Subjects
- *
BLOOD vessels , *ARTERIES , *MESENTERIC artery , *ADIPOSE tissues , *CANCER - Abstract
Peripancreatic lymphatic networks are frequently involved in pancreatobiliary carcinoma, affecting the prognosis. However, little attention has been paid to CT imaging of normal and pathological conditions of peripancreatic lymphatic networks. We evaluated multi-detector row CT (MDCT) images of peripancreatic lymphatic networks invaded by pancreatic carcinoma and compared them with those of normal peripancreatic lymphatic networks using imaging reconstruction every 1 mm with a multiplanar reformation technique. Apart from the region around the pancreatic body and tail, normal peripancreatic lymphatic networks were detected as "linear structures" on MDCT. However, peripancreatic lymphatic invasion by pancreatic carcinoma was frequently identified as "reticular," "tubular," or "soft tissue mass" appearances in the peripancreatic fat tissues. Peripancreatic lymphatic invasion by pancreatic carcinoma was more frequently detected around the common hepatic artery, celiac artery, superior mesenteric artery, and left para-aortic area. Depending on the tumor location, positive peripancreatic lymphatic invasion was most frequent at the area around the common hepatic artery in the head region and at the area around the celiac artery in the body and tail regions. Knowledge of CT imaging of normal and pathological peripancreatic lymphatic networks is essential for determining the accurate staging of pancreatic carcinoma. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF
4. Fibrous stroma and vascularity of pancreatic carcinoma: correlation with enhancement patterns on CT.
- Author
-
Hata, Hiroyuki, Mori, Hiromu, Matsumoto, Shunro, Yamada, Yasunari, Kiyosue, Hiro, Tanoue, Shuichi, Hongo, Norio, and Kashima, Kenji
- Subjects
- *
ABDOMINAL tumors , *METASTASIS , *CANCER invasiveness , *CYSTS (Pathology) , *LIVER cancer - Abstract
Objective: To demonstrate the contrast-enhancement behavior of pancreatic carcinoma on dynamic contrast-enhanced CT (DCE-CT), and the relationship between the degree of contrast-enhancement and the vascularity (vessel density) and amount of fibrous stroma (fibrosis within the tumor) on pathological specimen.Methods: The contrast-enhancement values were measured by producing the subtracting images for obtaining largest region of interests to reduce measurement errors and variability. Vascularity was determined by immunostaining of the tissue sections with factor 8 and the fibrous stroma was determined by picrosirius staining. Correlation of the findings of DCE-CT with pathological findings was performed in 21 patients with pancreatic carcinoma.Results: All but one patient exhibited a gradually increasing enhancement, but there was considerably wide range in contrast-enhancement values of tumors. Examination of the overall relationship between vascularity and fibrous stroma with contrast-enhancement behavior showed that tumor with more fibrosis and higher vascularity had a higher contrast effect through all phases of dynamic study. Tumors having liver metastases tended to be less fibrotic than tumors without liver metastases.Conclusion: The contrast-enhancement behavior of pancreatic carcinoma may be helpful in estimating vascularity and the extent of tumor fibrosis and possibility of liver metastases. [ABSTRACT FROM AUTHOR]- Published
- 2010
- Full Text
- View/download PDF
5. Imaging diagnosis of hepatic metastases of pancreatic carcinomas: significance of transient wedge-shaped contrast enhancement mimicking arterioportal shunt.
- Author
-
Gabata, Toshifumi, Matsui, Osamu, Terayama, Noboru, Kobayashi, Satoshi, and Sanada, Junichiro
- Subjects
- *
LIVER metastasis , *PANCREATIC cancer , *LIVER cancer , *MAGNETIC resonance imaging , *TOMOGRAPHY , *ARTERIOGRAPHY , *MEDICAL imaging systems - Abstract
We aimed to evaluate the imaging findings of hepatic metastases from pancreatic cancers, especially wedge-shaped enhancement and its etiology. Dynamic CT and MR images were performed in 87 patients with liver metastases from pancreatic carcinomas, and CT during arterial portography (CTAP) and CT during hepatic arteriography (CTHA) in 51 patients. Liver metastases were multiple in 84 patients (97%) and solitary in only three (3%). In 44 of 87 patients (51%), all liver metastases showed ring-like enhancement compatible with metastatic adenocarcinomas on dynamic CT and/or dynamic MR imaging. In 37 patients, more than one metastatic lesion showed wedge-shaped contrast enhancement on dynamic CT, dynamic MRI and CTHA, and wedge-shaped perfusion defect on CTAP adjacent to metastatic tumors. Six patients showed multiple wedge-shaped enhancements, which were initially diagnosed as multiple arterioportal shunts (AP shunts). However, metastatic tumors appeared within the area of wedge-shaped enhancement and increased in size on follow-up CT and/or MR images. After all, 43 of 87 patients (49%) had AP shunt like contrast enhancement adjacent to liver metastases. Liver metastases from pancreatic carcinomas frequently show transient wedge-shaped enhancement, and should not be misdiagnosed as nontumorous arterioportal shunts. [ABSTRACT FROM AUTHOR]
- Published
- 2008
- Full Text
- View/download PDF
6. Pancreatic carcinoma versus chronic focal pancreatitis: contrast-enhanced power Doppler ultrasonography findings.
- Author
-
Scialpi, M., Midiri, M., Bartolotta, T., Cazzolla, M., Rotondo, A., Resta, M., Lagalla, R., Cardinale, A., Bartolotta, T V, Cazzolla, M P, Resta, M C, and Cardinale, A E
- Subjects
- *
DOPPLER ultrasonography , *DIAGNOSTIC ultrasonic imaging , *PANCREATIC tumors , *PANCREATITIS , *DIAGNOSTIC imaging , *ULTRASONIC imaging - Abstract
Background: We assessed the potential usefulness of contrast-enhanced power Doppler ultrasonography (US) for differentiating pancreatic carcinoma from chronic focal pancreatitis.Methods: Twenty-six consecutive patients with ductal carcinoma (n=16) and chronic focal pancreatitis (n=10) underwent power Doppler US examinations before and after intravenous injection of an air-based contrast agent (Levovist, Schering, Berlin, Germany). Final diagnosis was obtained by surgery in all patients. The following parameters before and after intravenous administration of contrast agent were evaluated for each lesion: number, morphology and course of the vessels within the lesion and time to maximum detectable enhancement. Number of the lesion vessels and time to maximum enhancement for each lesion were compared by with Student t test.Results: After injection of contrast agent, nine of 16 (56.2%) carcinomas showed a larger total number of vessels (p<0.005) and faster enhancement (p<0.0001) compared with chronic focal pancreatitis. Irregular vessels with a serpiginous course that penetrated the tumor was predominant in carcinoma (eight of 16 cases), whereas focal pancreatitis presented mostly as avascular masses (five of 10 cases).Conclusion: Contrast-enhanced power Doppler US provides useful findings for differentiating pancreatic carcinoma from chronic focal pancreatitis. [ABSTRACT FROM AUTHOR]- Published
- 2005
- Full Text
- View/download PDF
7. Diffusion-weighed MR imaging of pancreatic carcinoma.
- Author
-
Matsuki, M., Inada, Y., Nakai, G., Tatsugami, F., Tanikake, M., Narabayashi, I., Masuda, D., Arisaka, Y., Takaori, K., and Tanigawa, N.
- Subjects
- *
MAGNETIC resonance imaging , *PANCREATIC cancer , *CANCER patients , *SCANNING systems , *PANCREATITIS - Abstract
The aim of this study was to demonstrate the feasibility of body diffusion-weighted (DW) MR imaging in the evaluation of a pancreatic carcinoma. In nine normal volunteers and in eight patients with pancreatic carcinoma, DW images were obtained on the axial plane scanning with a multisection spin-echo-type single-shot echo planar sequence with a body coil. Moreover, we measured the apparent diffusion coefficient (ADC) value in a circular region of interest (ROI) within the normal pancreas, pancreatic carcinoma, and tumor-associated chronic pancreatitis. On the DW images, all eight carcinomas were clearly shown as high signal intensity relative to the surrounding tissue. The ADC value (×10−3 mm2/s) in the carcinoma was 1.44 ± 0.20, which was significantly lower compared to that of normal pancreas (1.90 ± 0.06) and tumor-associated chronic pancreatitis (2.31 ± 0.18). Diffusion-weighted (DW) images can be helpful in detecting the pancreatic carcinoma and accessing the extent of the tumor. [ABSTRACT FROM AUTHOR]
- Published
- 2007
- Full Text
- View/download PDF
8. Tumor-associated focal chronic pancreatitis from invasion of the pancreatic duct by common bile duct carcinoma: radiologic–pathologic correlation.
- Author
-
Gabata, T., Sanada, J., Kobayashi, S., Terayama, N., Kadoya, M., and Matsui, O.
- Subjects
- *
PANCREATITIS , *CHOLANGIOCARCINOMA , *CANCER invasiveness , *BILIARY tract , *CANCER cell growth , *PANCREAS - Abstract
We report a case of tumor-associated focal chronic pancreatitis of the uncinate process of the pancreas. The chronic pancreatitis was secondary to stenosis of the main pancreatic duct from invasion by a common bile duct carcinoma. A feature distinguishing the chronic pancreatitis from pancreatic carcinoma was the localized dilatation of pancreatic duct branches evident in the focal lesion of the uncinate process. Correspondence to: T. Gabata --> [ABSTRACT FROM AUTHOR]
- Published
- 2003
- Full Text
- View/download PDF
9. Imaging diagnosis of hepatic metastases of pancreatic carcinomas: significance of transient wedge-shaped contrast enhancement mimicking arterioportal shunt
- Author
-
Junichiro Sanada, Toshifumi Gabata, Noboru Terayama, Satoshi Kobayashi, and Osamu Matsui
- Subjects
Adult ,Male ,Nephrology ,medicine.medical_specialty ,Pancreatic disease ,Urology ,Contrast Media ,Magnetic resonance angiography ,Diagnosis, Differential ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Liver metastasis ,Aged ,Aged, 80 and over ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Liver Neoplasms ,Angiography ,Gastroenterology ,Cancer ,General Medicine ,Middle Aged ,Hepatology ,medicine.disease ,Pancreatic Neoplasms ,Portal System ,Dynamic contrast-enhanced MRI ,Arterioportal shunt ,Female ,Radiology ,Tomography, X-Ray Computed ,Pancreatic carcinoma ,business ,Perfusion ,Magnetic Resonance Angiography ,CT ,MRI - Abstract
金沢大学医薬保健研究域医学系, We aimed to evaluate the imaging findings of hepatic metastases from pancreatic cancers, especially wedge-shaped enhancement and its etiology. Dynamic CT and MR images were performed in 87 patients with liver metastases from pancreatic carcinomas, and CT during arterial portography (CTAP) and CT during hepatic arteriography (CTHA) in 51 patients. Liver metastases were multiple in 84 patients (97%) and solitary in only three (3%). In 44 of 87 patients (51%), all liver metastases showed ring-like enhancement compatible with metastatic adenocarcinomas on dynamic CT and/or dynamic MR imaging. In 37 patients, more than one metastatic lesion showed wedge-shaped contrast enhancement on dynamic CT, dynamic MRI and CTHA, and wedge-shaped perfusion defect on CTAP adjacent to metastatic tumors. Six patients showed multiple wedge-shaped enhancements, which were initially diagnosed as multiple arterioportal shunts (AP shunts). However, metastatic tumors appeared within the area of wedge-shaped enhancement and increased in size on follow-up CT and/or MR images. After all, 43 of 87 patients (49%) had AP shunt like contrast enhancement adjacent to liver metastases. Liver metastases from pancreatic carcinomas frequently show transient wedge-shaped enhancement, and should not be misdiagnosed as nontumorous arterioportal shunts. © 2007 Springer Science+Business Media, LLC.
- Published
- 2007
- Full Text
- View/download PDF
10. Abdominal lymphoma: differentiation from pancreatic carcinoma with Doppler US
- Author
-
Tomoya Komatsuda, Kei Konno, Hiroko Naganuma, Hideaki Ishida, J. Ishida, Sumio Watanabe, and Michiko Sato
- Subjects
Adult ,Male ,medicine.medical_specialty ,Pathology ,Pancreatic disease ,Lymphoma ,Urology ,Diagnosis, Differential ,immune system diseases ,hemic and lymphatic diseases ,Internal medicine ,medicine ,Carcinoma ,Humans ,Radiology, Nuclear Medicine and imaging ,Pancreatic carcinoma ,Ultrasonography, Doppler, Color ,Aged ,Ultrasonography ,Radiological and Ultrasound Technology ,business.industry ,Gastroenterology ,General Medicine ,Middle Aged ,Hepatology ,medicine.disease ,Pancreatic Neoplasms ,medicine.anatomical_structure ,Abdominal Neoplasms ,Abdomen ,Female ,Radiology ,Doppler ultrasound ,business ,Pancreas - Abstract
Marked lymphadenopathy around the pancreas due to lymphoma (abdominal lymphoma) occasionally can mimic a total pancreatic carcinoma on ultrasonography (US). We investigated whether US and color Doppler US allowed differentiation between those pathologies.We analyzed the US and color Doppler results of 12 cases of abdominal peripancreatic lymphoma and 21 cases of total pancreatic carcinoma.With regard to shape, echogenicity of the lesion, and mode of vascular involvement, there was no difference between groups. With regard to maximal velocities and resistive indices of the involved vessels, there was no difference between groups. However, the presence of turbulent flows in the involved vessels was seen exclusively in the pancreatic carcinoma group.The presence or absence of turbulent flow in the involved vessels is a very important finding for differentiating abdominal lymphomas from total pancreatic carcinomas.
- Published
- 2002
- Full Text
- View/download PDF
11. Uncommon pancreatic tumors and pseudotumors
- Author
-
Alampady Krishna Prasad Shanbhogue, Monica Ragucci, Manjiri Dighe, Lorenzo Di Cesare Mannelli, Dhakshina Ganeshan, Hina Arif Tiwari, Serena Monti, Srinivasa R. Prasad, Suresh Maximin, and Neeraj Lalwani
- Subjects
Diagnostic Imaging ,medicine.medical_specialty ,Pathology ,Urology ,Diagnosis, Differential ,Internal medicine ,medicine ,Neoplasm ,Humans ,Radiology, Nuclear Medicine and imaging ,Pancreatic carcinoma ,Pancreas ,Ultrasonography ,Heterogeneous group ,Radiological and Ultrasound Technology ,business.industry ,Gastroenterology ,Pancreatic Diseases ,General Medicine ,Hepatology ,medicine.disease ,Patient management ,Pancreatic Neoplasms ,medicine.anatomical_structure ,Adenocarcinoma ,Radiology ,business ,Tomography, X-Ray Computed - Abstract
A heterogeneous group of uncommon neoplastic and non-neoplastic pancreatic pathologies exists that can mimic pancreatic adenocarcinoma. These “imitators” are unique and may demonstrate characteristic clinical and imaging features. Imaging characteristics of some of these diverse lesions are not well described in the literature, and erroneous diagnoses of these entities as pancreatic carcinoma may be responsible for unnecessary surgeries. Knowledge of these selected pancreatic pathologies is essential to facilitate optimal patient management.
- Published
- 2014
12. Assessment of resectability of pancreatic carcinoma by color Doppler sonography
- Author
-
Kei Konno, Hiroko Naganuma, Yuki Hamashima, Tomoya Komatsuda, Osamu Masamune, Michiko Sato, Hideaki Ishida, and J. Ishida
- Subjects
Adult ,Male ,medicine.medical_specialty ,Pancreatic disease ,Urology ,Sensitivity and Specificity ,Predictive Value of Tests ,Internal medicine ,Carcinoma ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Pancreatic carcinoma ,Ultrasonography, Doppler, Color ,Aged ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Color image ,Angiography ,Gastroenterology ,General Medicine ,Color doppler ,Middle Aged ,Hepatology ,medicine.disease ,Pancreatic Neoplasms ,medicine.anatomical_structure ,Female ,Radiology ,business ,Pancreas - Abstract
This study was undertaken to evaluate the role of color Doppler sonography in the preoperative assessment of vascular involvement in patients with pancreatic carcinoma. Twenty-six pancreatic carcinomas were investigated with color Doppler sonography and angiography, and the results of these examinations were compared with those of surgical findings. Color Doppler sonography was more sensitive than angiography in depicting vascular involvement of carcinoma. Thus, it seems rational to perform a preoperative assessment in suspected pancreatic carcinoma patients initially with color Doppler sonography to improve patient management.
- Published
- 1999
- Full Text
- View/download PDF
13. Recurrent pancreatic carcinoma and cholangiocarcinoma: 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT)
- Author
-
Daniel M. Labow, Sasan Roayaie, Lale Kostakoglu, Steven Peti, Sivan Golan, Katherine L. Cameron, and William L. Simpson
- Subjects
medicine.medical_specialty ,Urology ,Computed tomography ,Multimodal Imaging ,Fluorodeoxyglucose positron emission tomography ,Cholangiocarcinoma ,Recurrent Pancreatic Carcinoma ,Fluorodeoxyglucose F18 ,medicine ,Carcinoma ,Humans ,Radiology, Nuclear Medicine and imaging ,Ct findings ,Pancreatic carcinoma ,PET-CT ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,General Medicine ,medicine.disease ,Pancreatic Neoplasms ,Positron emission tomography ,Positron-Emission Tomography ,Radiology ,Neoplasm Recurrence, Local ,Radiopharmaceuticals ,Nuclear medicine ,business ,Tomography, X-Ray Computed - Abstract
Although the current literature is limited, available data suggest that (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) imaging improves the evaluation of patients with recurrent pancreatic carcinoma and cholangiocarcinoma. There is evidence that PET/CT is particularly useful in the setting of elevated tumor markers and negative or equivocal CT findings. This article reviews the nature of these carcinomas in the post-therapy setting and describes the strengths and limitations of PET/CT when used for monitoring recurrence.
- Published
- 2011
14. Evaluation of pancreatic carcinoma with FDG PET
- Author
-
Alan J. Fischman and Hossein Jadvar
- Subjects
Adult ,Male ,medicine.medical_specialty ,Pancreatic disease ,Urology ,Diagnosis, Differential ,Fluorodeoxyglucose F18 ,Internal medicine ,Carcinoma ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Antigens, Tumor-Associated, Carbohydrate ,Pancreatic carcinoma ,Aged ,Retrospective Studies ,Fluorodeoxyglucose ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,Magnetic resonance imaging ,General Medicine ,Hepatology ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,Pancreatic Neoplasms ,medicine.anatomical_structure ,Positron emission tomography ,Female ,Radiology ,Radiopharmaceuticals ,Pancreas ,Nuclear medicine ,business ,Tomography, X-Ray Computed ,medicine.drug ,Carcinoma, Pancreatic Ductal ,Tomography, Emission-Computed - Abstract
To assess the diagnostic usefulness and clinical impact of positron emission tomography with [F-18]fluorodeoxyglucose (FDG PET) on the management of patients with known or suspected pancreatic carcinoma.Attenuation-corrected FDG PET was performed in 20 patients (12 male, eight female) with pancreatic carcinoma at the time of initial diagnosis (n = 7), for tumor surveillance after Whipple surgery (n = 11), and for reevaluation after chemoradiation therapy (n = 2). Visual analysis of PET images were correlated with the results of abdominal computed tomography (CT) and carbohydrate antigen (CA) 19-9 serum tumor marker level that were obtained within 1 month of the PET study. Diagnostic validation was by histology in nine patients and by clinical or radiologic follow-up (5-48 months) in 11 patients. Changes in therapeutic management that were prompted by PET were tabulated.PET was concordant with the findings of abdominal CT in 14 patients (13 true positive, 1 true negative). PET detected clinically unsuspected lung lesions, confirmed subsequently by a chest CT, in one of these 14 patients. PET was discordant with CT in six patients. PET detected tumor recurrence in three patients in this group (15% of total) with nondiagnostic CT findings and elevated CA 19-9 serology. In two of these three patients, chemotherapy with gemcitabine was initiated based on PET localization of disease. Tumor was confirmed in the remaining one of the three patients at autopsy shortly after the PET study. FDG localization in a displaced loop of bowel resulted in an apparent false-positive hepatic lesion in one of six patients in the discordant group. PET underestimated the extent of metastatic disease in the remaining two of six patients due to hyperglycemia.In patients with suspected pancreatic carcinoma at the time of initial presentation, PET is complementary to abdominal CT and allows detection of unsuspected distant metastases. In patients with suspected recurrent pancreatic carcinoma, based on elevated or rising CA 19-9 serology, PET can localize the disease when abdominal CT is nondiagnostic as a result of posttherapy anatomic alteration. Imaging evaluation with PET may impact the clinical management of patients with pancreatic carcinoma.
- Published
- 2001
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.