1. Early-stage clear cell tubulopapillary renal cell carcinoma: imaging features and distinction from clear cell and papillary subtypes
- Author
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Atul B. Shinagare, Stuart G. Silverman, Michelle S. Hirsch, V. Anik Sahni, and Gevork N. Mnatzakanian
- Subjects
Male ,Pathology ,medicine.medical_specialty ,Urology ,Contrast Media ,Sensitivity and Specificity ,030218 nuclear medicine & medical imaging ,Diagnosis, Differential ,03 medical and health sciences ,0302 clinical medicine ,Renal cell carcinoma ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Stage (cooking) ,Carcinoma, Renal Cell ,Aged ,Neoplasm Staging ,Retrospective Studies ,Aged, 80 and over ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,Receiver operating characteristic ,business.industry ,Gastroenterology ,Cancer ,Magnetic resonance imaging ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,Carcinoma, Papillary ,Kidney Neoplasms ,Exact test ,030220 oncology & carcinogenesis ,Female ,Differential diagnosis ,Neoplasm Grading ,Nuclear medicine ,business ,Tomography, X-Ray Computed ,Clear cell - Abstract
Clear cell tubulopapillary renal cell carcinoma (CCTPRCC) is a recently described, low-grade subtype of renal cancer. We determined if imaging features could be used to distinguish early-stage CCTPRCC from stage-matched clear cell RCC (ccRCC) and papillary RCC (pRCC). This IRB-approved retrospective study included 54 stage T1a patients with pathologically confirmed CCTPRCC (n = 18), ccRCC (n = 18), and pRCC (n = 18). CT (n = 48) and MRI (n = 27) exams were reviewed and imaging features compared. Continuous variables were evaluated using ANOVA and Tukey’s multiple comparison tests. Categorical variables were compared using Chi-square test or Fisher’s exact test. Compared to pRCC, CCTPRCC had a lower mean attenuation value on unenhanced CT (p
- Published
- 2016