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Start Over Author "Corey J. Bishop" Journal acs applied bio materials
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1. Polymer-Coated Extracellular Vesicles for Selective Codelivery of Chemotherapeutics and siRNA to Cancer Cells

Author

Yong Yu Jhan, Guillermo Palou Zuniga, Corey J. Bishop, Akhilesh K. Gaharwar, Kanwar Abhay Singh, and Daniel L. Alge

Subjects
Lung Neoplasms, High interest, Polymers, Biomedical Engineering, Antineoplastic Agents, Gene delivery, Extracellular vesicles, Biomaterials, Extracellular Vesicles, Drug Delivery Systems, Humans, Gene silencing, RNA, Small Interfering, Drug Carriers, Chemistry, Biochemistry (medical), RNA, General Chemistry, Microvesicles, Cancer treatment, A549 Cells, Doxorubicin, Cancer cell, Cancer research, Nanoparticles, RNA Interference
Abstract

Combination therapies involving small-interfering RNA (siRNA)-mediated gene silencing and small-molecule drugs are of high interest for cancer treatment. Among the current gene delivery carriers, cell-derived extracellular vesicles (EVs) are particularly promising candidates due to their high biocompatibility, low immunogenicity

Published
2021
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