1. Emerging Phospholipid Nanobiomaterials for Biomedical Applications to Lab-on-a-Chip, Drug Delivery, and Cellular Engineering
- Author
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Maedeh Rahimnejad, S. Mohammad Sajadi, Sepideh Jahangiri, Woosung Kwon, Sei Kwang Hahn, Sepideh Ahmadi, Omid Akhavan, Mohammad Reza Saeb, Mungu Kim, and Navid Rabiee
- Subjects
Drug Carriers ,Engineering ,Microscopy, Confocal ,SARS-CoV-2 ,business.industry ,Biochemistry (medical) ,Biomedical Engineering ,COVID-19 ,Biocompatible Materials ,Nanotechnology ,Biosensing Techniques ,General Chemistry ,Lab-on-a-chip ,Nanostructures ,COVID-19 Drug Treatment ,Cellular engineering ,law.invention ,Biomaterials ,law ,Lab-On-A-Chip Devices ,Drug delivery ,Humans ,business ,Phospholipids - Abstract
The design of advanced nanobiomaterials to improve analytical accuracy and therapeutic efficacy has become an important prerequisite for the development of innovative nanomedicines. Recently, phospholipid nanobiomaterials including 2-methacryloyloxyethyl phosphorylcholine (MPC) have attracted great attention with remarkable characteristics such as resistance to nonspecific protein adsorption and cell adhesion for various biomedical applications. Despite many recent reports, there is a lack of comprehensive review on the phospholipid nanobiomaterials from synthesis to diagnostic and therapeutic applications. Here, we review the synthesis and characterization of phospholipid nanobiomaterials focusing on MPC polymers and highlight their attractive potentials for applications in micro/nanofabricated fluidic devices, biosensors, lab-on-a-chip, drug delivery systems (DDSs), COVID-19 potential usages for early diagnosis and even treatment, and artificial extracellular matrix scaffolds for cellular engineering.
- Published
- 2021
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