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Your search keyword '"Liu, Shuwei"' showing total 15 results
Start Over Author "Liu, Shuwei" Journal acs applied materials & interfaces
15 results on '"Liu, Shuwei"'

2. Correction to “Cu2+-Loaded Polydopamine Nanoparticles for Magnetic Resonance Imaging-Guided pH- and Near-Infrared-Light-Stimulated Thermochemotherapy”

Author

Ge, Rui, primary, Lin, Min, additional, Li, Xing, additional, Liu, Shuwei, additional, Wang, Wenjing, additional, Li, Shuyao, additional, Zhang, Xue, additional, Liu, Yi, additional, Liu, Lidi, additional, Shi, Feng, additional, Sun, Hongchen, additional, Zhang, Hao, additional, and Yang, Bai, additional

Published
2021
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6. Cu(II)-Doped Polydopamine-Coated Gold Nanorods for Tumor Theranostics

Author

Liu, Shuwei, Wang, Lu, Lin, Min, Wang, Dandan, Song, Ziqi, Li, Shuyao, Ge, Rui, Zhang, Xue, Liu, Yi, Li, Zhimin, Sun, Hongchen, Yang, Bai, and Zhang, Hao

Abstract

Gold nanorods (AuNRs) are potentially useful in tumor theranostics, but the poor stability, high toxicity, and rapid removal by the immune system seriously limit their theranostic applications. In our study, we demonstrate the fabrication of Cu(II)-doped polydopamine-coated AuNR (AuNR@CuPDA), which significantly improves the potentials in tumor theranostics. Besides the improvement of physiological stability and biocompatibility, the PDA shell increases the photothermal performance and prolongs the blood circulation time of AuNRs. The half-life of AuNRs during blood circulation increases from 0.7 to 4.5 h after PDA coating, and the injected dose per gram of tumor tissue is 4.6% ID g–1for AuNR@CuPDA. In addition to computer tomography imaging, the loading of Cu(II) in PDA shell endows AuNR@CuPDA with magnetic resonance imaging function. Cu(II) doped in PDA shell also exhibits chemotherapeutic behavior, and the tumor inhibitor rate is 31.2%. Further combining 808 nm laser-driven photothermal therapy, tumors were completely ablated, and no recurrence was observed. Liver and renal functions tests and histological analysis of major organs confirm that AuNR@CuPDA is in good safety.

Published
2024
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7. Cu(II)-Doped Polydopamine-Coated Gold Nanorods for Tumor Theranostics

Author

Liu, Shuwei, primary, Wang, Lu, additional, Lin, Min, additional, Wang, Dandan, additional, Song, Ziqi, additional, Li, Shuyao, additional, Ge, Rui, additional, Zhang, Xue, additional, Liu, Yi, additional, Li, Zhimin, additional, Sun, Hongchen, additional, Yang, Bai, additional, and Zhang, Hao, additional

Published
2017
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14. Fe3O4@polydopamine Composite Theranostic Superparticles Employing Preassembled Fe3O4Nanoparticles as the Core

Author

Ge, Rui, Li, Xing, Lin, Min, Wang, Dandan, Li, Shuyao, Liu, Shuwei, Tang, Qi, Liu, Yi, Jiang, Jinlan, Liu, Lidi, Sun, Hongchen, Zhang, Hao, and Yang, Bai

Abstract

Iron oxide (Fe3O4), polydopamine (PDA), and in particular their composites are examples of the safest nanomaterials for developing multifunctional nanodevices to perform noninvasive tumor diagnosis and therapy. However, the structures and performances of Fe3O4–PDA nanocomposites should be further perfected to enhance the theranostic efficiency. In this work, we demonstrate the fabrication of PDA-capped Fe3O4(Fe3O4@PDA) superparticles (SPs) employing preassembled Fe3O4nanoparticles (NPs) as the cores. Owing to the collective effect of preassembled Fe3O4NPs, the superparamagnetism and photothermal performance of Fe3O4@PDA SPs are greatly enhanced, thus producing nanodevices with improved magnetic resonance imaging (MRI)-guided photothermal efficiency. Systematical studies reveal that the molar extinction coefficient of the as-assembled Fe3O4SPs is 3 orders of magnitude higher than that of individual Fe3O4NPs. Also due to the high aggregation degree of Fe3O4NPs, the T2-weighted MRI contrast is greatly enhanced for the SPs with r2relaxivity of 230.5 mM–1s–1, which is ∼2.5 times larger than that of individual Fe3O4NPs. The photothermal stability, physiological stability, and biocompatibility, as well as the photothermal performance of Fe3O4SPs, are further improved by enveloping with PDA shell.

Published
2016
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