1. Delivery of Cargo with a Bioelectronic Trigger.
- Author
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Hemmatian Z, Jalilian E, Lee S, Strakosas X, Khademhosseini A, Almutairi A, Shin SR, and Rolandi M
- Abstract
Biological systems exchange information often with chemical signals. Here, we demonstrate the chemical delivery of a fluorescent label using a bioelectronic trigger. Acid-sensitive microparticles release fluorescin diacetate upon low pH induced by a bioelectronic device. Cardiac fibroblast cells (CFs) uptake fluorescin diacetate, which transforms into fluorescein and emits a fluorescent signal. This proof-of-concept bioelectronic triggered delivery may be used in the future for real-time programming and control of cells and cell systems.
- Published
- 2018
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