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2. Practical Method for Preparation of (S)‑2-Amino-5,5,5-trifluoropentanoic Acid via Dynamic Kinetic Resolution

Author

Hidenori Abe, Hiroki Moriwaki, Toshio Miwa, Vadim A. Soloshonok, Yutaka Minamitsuji, Haibo Mei, Ryosuke Takeda, Jianlin Han, and Tsubasa Sakamoto

Subjects
lcsh:Chemistry, Work (thermodynamics), Materials science, Scale (ratio), lcsh:QD1-999, General Chemical Engineering, General Chemistry, Biological system, Kinetic resolution
Abstract

This work reports an operationally convenient ∼20 g scale synthesis of (S)-2-amino-5,5,5-trifluoropentanoic acid and its Fmoc-derivative via dynamic kinetic resolution of the corresponding racemate.

Published
2019

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