The analytical efficacy of five gas mixers and five stabilizers on signal stabilization and washout time obtained for laser ablation inductively coupled plasma mass spectrometry (LA-ICPMS) was evaluated in the present study. In the case of gas mixers examined, a total of 95 patterns of their attitudes as well as different directions of the gas flows were examined, and it was found that the signal variation and the washout time were strongly dependent on these factors. Even in a simple Y-shaped fitting (Y-mixer), signal stability and washout time had large variations with respect to its different attitudes as well as gas flow directions. The shortest washout time for each gas mixer was almost the same ranging from 1.0 to 1.2 s. The signal variations observed were 11-15% of relative standard deviation (RSD) under optimum conditions for each gas mixer. The optimum condition of a Y-mixer for LA-ICPMS represented 11% RSD and 1.0 s for signal variation and washout time, respectively. In the case of stabilizers examined, almost all stabilizers improved signal variations from 11 to 3.0-9.3%, but washout times became longer than those of the only Y-mixer from 1.0 to 1.2-8.9 s. The important thing is that the signal stability and the washout time are trade-off correlations for gas mixers and stabilizers. A suitable gas mixer or a stabilizer on the trade-off line can be selected with respect to different applications. It was also observed that variations of both signal stability and washout time correlated with the volume of stabilizers despite their different inner structures; that is, a stable signal and longer washout time seemed to be observed when the volume of the chamber became larger. This suggested that the signal stabilization obtained by stabilizers was ascribable to not only elimination of larger particles from laser ablation but also particle mixing effect, which compensated signal variation.