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Your search keyword '"Lin, Ching-Ting"' showing total 2 results
Start Over Author "Lin, Ching-Ting" Journal acta crystallographica: section f (wiley-blackwell)
2 results on '"Lin, Ching-Ting"'

2. Crystallization and preliminary X-ray diffraction analysis of the DNA-binding domain of the response regulator SaeR from Staphylococcus epidermidis.

Author

Chen, Sheng-Chia, Huang, Chi-Hung, Chen, Yu-Ren, Yang, Chia Shin, Lin, Ching-Ting, and Chen, Yeh

Subjects
*STAPHYLOCOCCUS epidermidis, *CRYSTALS, *DNA-binding proteins, *NOSOCOMIAL infections, *ANTIBIOTICS, *GENOMES
Abstract

SaeR is the response regulator of the SaeRS two-component signal transduction system, which is involved in regulating bacterial autolysis and biofilm formation. SaeR comprises an N-terminal receiver domain and a C-terminal effector domain. The effector domain possesses DNA-binding and transactivation functions. Here, the effector domain of SaeR from Staphylococcus epidermidis was purified and crystallized using the sitting-drop vapour-diffusion method. The crystals diffracted to a resolution of 2.15 Å and belonged to space group P212121, with unit-cell parameters a = 34.20, b = 53.78, c = 111.66 Å. Determining the structure will provide insights into the mechanisms underlying DNA binding. [ABSTRACT FROM AUTHOR]

Published
2013
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