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The title compound N -(4-meth-oxy-phen-yl)-2-[4-(3-oxo-3-phenyl-prop-1-en-1-yl)phen-oxy]acetamide, C 24 H 21 NO 4 , was prepared from reaction of N -(4-meth-oxy-phen-yl)-2-chloro-acetamide and ( E )-3-(4-hy-droxy-phen-yl)-1-phenyl-prop-2-en-1-one, which was obtained from the reaction of 4-hy-droxy-benzaldehyde and aceto-phenone. The structure of the title compound was determined by IR, 1 H-NMR, 13 C-NMR and HR-MS spectroscopic data and further characterized by single-crystal X-ray diffraction. The asymmetric unit contains four mol-ecules, each displaying an E -configuration of the C=C bond. The dihedral angle between the phenyl rings in each mol-ecule varies between 14.9 (2) and 45.8 (2)°. In the crystal, C-H⋯O hydrogen-bonding inter-actions link the mol-ecules into chains running along the [001] direction. In addition, C-H⋯π inter-actions further stabilize the crystal packing. A Hirshfeld analysis indicates that the most important contributions to the surface contacts are from H⋯H (43.6%), C⋯H/H⋯C (32.1%) and O⋯H/H⋯O (18.1%) inter-actions., (© Nguyen Tien et al. 2021.) more...

The title compound, C 18 H 16 N 2 O 3 S, was synthesized by reaction of 2-mercapto-3-phenyl-quinazolin-4(3 H )-one with ethyl chloro-acetate. The quinazoline ring forms a dihedral angle of 86.83 (5)° with the phenyl ring. The terminal methyl group is disordered by a rotation of about 60° in a 0.531 (13): 0.469 (13) ratio. In the crystal, C-H⋯O hydrogen-bonding inter-actions result in the formation of columns running in the [010] direction. Two parallel columns further inter-act by C-H⋯O hydrogen bonds. The most important contributions to the surface contacts are from H⋯H (48.4%), C⋯H/H⋯C (21.5%) and O⋯H/H⋯O (18.7%) inter-actions, as concluded from a Hirshfeld analysis., (© Nguyen Tien et al. 2020.) more...

In the title compound, C 15 H 14 IN 3 O 2 ·CH 3 OH, two aromatic rings are linked by an N -substituted hydrazide function. The dihedral angle between the aromatic rings is 10.53 (8)°. The stereochemistry about the imine function is E . The methanol mol-ecule forms an O-H⋯O hydrogen bond to the hydrazide O atom. In the crystal, chains of mol-ecules running along the c -axis direction are formed by O-H⋯O hydrogen bonds. Adjacent chains are linked through N-H⋯O hydrogen bonds and π-π stacking inter-actions. The inter-molecular inter-actions in the crystal packing were investigated using Hirshfeld surface analysis, which indicated that the most significant contacts are H⋯H (38.2%), followed by C⋯H/H⋯C (20.6%), O⋯H/H⋯O (11.1%) and I⋯H/H⋯I (9.7%). more...

The title compound, C 9 H 8 N 2 O 2 S 3 , crystallizes with two mol-ecules ( A and B ) in the asymmetric unit. Both have similar conformations (overlay r.m.s. deviation = 0.209 Å) and are linked by an N-H⋯O hydrogen bond. In both mol-ecules, the thio-phene rings show orientational disorder, with occupancy factors of 0.6727 (17) and 0.3273 (17) for mol-ecule A , and 0.7916 (19) and 0.2084 (19) for mol-ecule B . The five-membered rings make an angle of 79.7 (2)° in mol-ecule A and an angle of 66.8 (2)° in mol-ecule B . In the crystal, chains of mol-ecules running along the a -axis direction are linked by N-H⋯O hydrogen bonds. The inter-action of adjacent chains through N-H⋯O hydrogen bonds leads to two types of ring structures containing four mol-ecules and described by the graph-set motifs R 4 4 (18) and R 4 2 (14). more...