1. 2-(4-Fluoroanilino)-3-(2-hydroxyethyl)quinazolin-4(3H)-one
- Author
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Xue-Mei Chen, Qian Zhang, Bin Liu, Ling-Hua Xu, Yuan-Hong Jiao, and Min Ruan
- Subjects
chemistry.chemical_compound ,Hydrogen bond ,Chemistry ,General Materials Science ,General Chemistry ,Crystal structure ,Dihedral angle ,Condensed Matter Physics ,Bioinformatics ,Benzene ,Organic Papers ,Medicinal chemistry - Abstract
The mol-ecular and crystal structures of the title compound, C(16)H(14)FN(3)O(2), are stabilized by intra-molecular N-H⋯O and inter-molecular O-H⋯O hydrogen bonds. The existence of non-classical intra-molecular C-H⋯N hydrogen bonds provides a dihedral angle between the fluoro-substituted benzene and pyrimidinone rings of 7.9 (1)°.
- Published
- 2009
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