18 results on '"Åke, Svensson"'
Search Results
2. Incidence Rate of Hand Eczema in Different Occupations: A Systematic Review and Meta-analysis
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Wasim, Jamil, Åke, Svensson, Anna, Josefson, Magnus, Lindberg, and Laura, Von Kobyletzki
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Male ,Incidence ,Eczema ,Humans ,Female ,Occupations - Abstract
Hand eczema is a chronic disease that results in economic and psychosocial burdens. The aim of this study was to systematically review and assess the magnitude of the association between exposure related to occupations and the incidence rate of hand eczema. A systematic search in PubMed, EMBASE, CINAHL and Cochrane databases, from inception to September 2017, of full-text observational studies reporting incident cases of hand eczema during employment, and a supplementary search in PubMed to September 2020, were conducted. Among 2,417 screened abstracts, 15 studies fulfilled the inclusion criteria. Incidence rates were reported per 100 person-years. Based on the Newcastle-Ottawa Scale, 9 studies were good quality, 2 fair quality, and 4 poor quality. Hairdressers had a high incidence of hand eczema of 21.4 (95% confidence interval [CI] 15.3-27.4), as did nurses, 16.9 (95% CI 11.2-22.7), and metal workers, 12.4 (95% CI 3.5-21.3). Hairdressers were predominantly women, and metal worker were predominantly men. Office occupations had an incidence rate of hand eczema of 4.9 (95% CI 1.2-9.6). The high risk of hand eczema for hairdressers, nurses, and metal workers, should be considered by healthcare policymakers. Even occupations with low irritant profile, such as office workers, were at risk of developing hand eczema, and more occupations should be investigated regarding the related risk of developing hand eczema.
- Published
- 2022
3. Burden of Atopic Dermatitis in Swedish Adults: A Population-based Study
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Åke Svensson, Grigorios Theodosiou, Florence J Dalgard, Scott Montgomery, Laura von Kobyletzki, and Alexandra Metsini
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Adult ,Male ,medicine.medical_specialty ,Adolescent ,Social Determinants of Health ,Comorbidity ,Dermatology ,Anxiety ,Severity of Illness Index ,Dermatitis, Atopic ,educational status ,Young Adult ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Cost of Illness ,Risk Factors ,Internal medicine ,Epidemiology ,Prevalence ,medicine ,Humans ,030212 general & internal medicine ,Depression (differential diagnoses) ,Aged ,Asthma ,Sweden ,global burden of disease ,atopic dermatitis ,Depression ,business.industry ,General Medicine ,Atopic dermatitis ,Middle Aged ,medicine.disease ,Health Surveys ,Confidence interval ,Population based study ,Cross-Sectional Studies ,Mental Health ,Relative risk ,RL1-803 ,Income ,Female ,epidemiology ,medicine.symptom ,business - Abstract
The burden of atopic dermatitis (AD) was assessed. A population-based, cross-sectional questionnaire study was performed among 34,313 Swedish adults in 2017. The prevalence of AD was 14%. Adults with mild AD had an increased relative risk ratio (RRR) of severe depression (aRRR 1.78, 95% confidence interval (95% CI) 1.50-2.12) and anxiety (aRRR 1.97, 95% CI 1.69-2.30), which was higher for severe AD (aRRR 6.22 95% CI 4.60- 8.42, aRRR 5.62 95% CI 4.10-7.71, respectively). Persons with severe AD were less likely to have a university degree (aRRR 0.55, 95% CI 0.34-0.90) and more likely to have a lower annual income (238,000-324,000 SEK: aRRR 0.51, 95% CI 0.39-0.77; 325,000 SEK or more 0.36; 0.25-0.58) compared with individuals without AD. These results suggest that AD implies an increased prevalence of comorbid mental conditions and an adverse impact on academic achievement and work. These adverse associations increase substantially for patients with severe AD and comorbid asthma.
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- 2019
4. Prevalence and Incidence of Atopic Dermatitis: A Systematic Review
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Åke Svensson, Simon Bylund, Laura B von Kobyletzki, and Marika Svalstedt
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0301 basic medicine ,Adult ,Male ,medicine.medical_specialty ,Adolescent ,Dermatology ,Dermatitis, Atopic ,030207 dermatology & venereal diseases ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Age Distribution ,systematic review ,Epidemiology ,medicine ,Prevalence ,Humans ,Child ,Aged ,Data abstraction ,Aged, 80 and over ,Study quality ,atopic dermatitis ,business.industry ,Incidence (epidemiology) ,Incidence ,Infant, Newborn ,Infant ,General Medicine ,Atopic dermatitis ,Middle Aged ,medicine.disease ,Confidence interval ,030104 developmental biology ,RL1-803 ,Child, Preschool ,Female ,business ,Demography ,Systematic search - Abstract
The primary objective of this study was to systematically review and analyse epidemiological studies of the prevalence and incidence of atopic dermatitis (AD) during childhood and adulthood, focusing on data from the 21st century. A systematic search of PubMed, EMBASE and Google (manual search) was performed in June 2019, followed by data abstraction and study quality assessment (Newcastle–Ottawa Scale). Cross-sectional and longitudinal epidemiological studies of individuals with AD (doctor-diagnosed or standardized definition) were included. Of 7,207 references reviewed, 378 moderate/good-quality studies were included: 352 on prevalence of AD and 26 on incidence of AD. In the 21st century, the 1-year prevalence of doctor-diagnosed AD ranged from 1.2% in Asia to 17.1% in Europe in adults, and 0.96% to 22.6% in children in Asia. The 1-year incidence ranged from 10.2 (95% confidence interval (95% CI) 9.9–10.6) in Italy to 95.6 (95% CI 93.4–97.9) per 1,000 person-years in children in Scotland. There were few recent studies on incidence of AD in the 21st century and no studies on adults only; most studies were conducted in Europe and the USA. Epidemiological studies on childhood and adulthood AD in different continents are still needed, especially on the incidence of AD during adulthood.
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- 2020
5. Subjective and Objective Characteristics of Patients Seen at a Psychodermatology Unit: One-year Experience in Malmö, Sweden
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Johan Fhager, Åke Svensson, Ewa Wallin, Karin Sjöström, Florence J Dalgard, and Inese Dubnika Hauksson
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Adult ,Male ,medicine.medical_specialty ,Pediatrics ,Dermatology ,Anxiety ,Hospital Anxiety and Depression Scale ,Personality Disorders ,Skin Diseases ,030207 dermatology & venereal diseases ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Surveys and Questionnaires ,Epidemiology ,medicine ,lcsh:Dermatology ,Humans ,signs ,Depression (differential diagnoses) ,Aged ,Retrospective Studies ,Psychiatric Status Rating Scales ,Sweden ,Schizophrenia, Paranoid ,Delusional disorder ,business.industry ,Depression ,Mood Disorders ,Mental Disorders ,Pruritus ,healthcare services ,General Medicine ,Psychodermatology ,Dermatology Life Quality Index ,lcsh:RL1-803 ,Middle Aged ,medicine.disease ,psychodermatology ,Mood disorders ,030220 oncology & carcinogenesis ,Quality of Life ,symptoms ,Female ,medicine.symptom ,business - Abstract
Clinical epidemiological knowledge concerning psychodermatology patients is scarce. The objective of this study was to assess morbidity in a new psychodermatology service. Information was gathered from patient records at the psychodermatology unit in Skane University Hospital, Malmo, Sweden, from 1 February 2017 to 31 January 2018. All patients were screened with the Hospital Anxiety and Depression Scale (HADS) and the Dermatology Life Quality Index (DLQI) at baseline and after 12 months. Additional information was collated from the patient records. A total of 50 patients were treated during the 12 months, 86% were women, mean age 44 years (standard deviation (SD) 16 years). Itch was present in 72% of patients. Forty-two percent of patients were diagnosed with mood disorders, 30% with personality disorders, and 16% with delusional disorders. At baseline 40% of patients had a DLQI score >11, clinical depression was present in 14%, and clinical anxiety in 28%. These data emphasize the need for access to a multidisciplinary unit for dermatology patients.
- Published
- 2020
6. Risk Factors for Penile Intraepithelial Neoplasia: A Population-based Register Study in Sweden, 2000-2012
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Åke Svensson, Carina Bjartling, Sinja Kristiansen, Linda Drevin, Ola Forslund, and Christian Torbrand
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Adult ,Male ,medicine.medical_specialty ,Adolescent ,Dermatology ,Risk Assessment ,Organ transplantation ,Genital warts ,030207 dermatology & venereal diseases ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Risk Factors ,medicine ,Penile cancer ,Humans ,Registries ,Risk factor ,Penile Neoplasms ,Aged ,CIS ,Aged, 80 and over ,Sweden ,lichen planus ,business.industry ,penile intraepithelial neoplasia ,Balanitis ,General Medicine ,Odds ratio ,Middle Aged ,penile cancer ,medicine.disease ,PeIN ,RL1-803 ,030220 oncology & carcinogenesis ,Case-Control Studies ,Cohort ,Penile Intraepithelial Neoplasia ,business ,Carcinoma in Situ ,penile cancer in situ - Abstract
Studies on risk factors for penile intraepithelial neoplasia have been small in size, have not distinguished penile intraepithelial neoplasia from invasive cancer, and have relied on self-reported information. This study investigated risk factors for penile intraepithelial neoplasia in a cohort of 580 penile intraepithelial neoplasia cases and 3,436 controls using information from 7 Swedish registers. Cases with penile intraepithelial neoplasia had increased odds ratios (ORs) for inflammatory skin diseases (14.7, 95% CI 6.5–33.4) including lichen planus (12.0, 95% CI 3.0–48.0), indicating lichen planus to be an important risk factor. Increased ORs were also observed for diseases of the prepuce (4.0, 95% CI 2.2–7.4), immunosuppressive drugs (5.0, 95% CI 2.5–9.8), penile surgical procedures (4.8, 95% CI 2.2–10.8), balanitis (9.2, 95% CI 5.0–16.8), genital warts (9.9, 95% CI 4.3−22.7) and organ transplantation (7.0, 95% CI 2.4–20.8). This study demonstrates important risk factors for penile intraepithelial neoplasia, providing knowledge that can help prevent the development of penile cancer.
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- 2018
7. Methotrexate-associated Sexual Dysfunction: Two Case Reports
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Åke Svensson and Grigorios Theodosiou
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musculoskeletal diseases ,Male ,medicine.medical_specialty ,Libido ,MEDLINE ,Dermatology ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Erectile Dysfunction ,Internal medicine ,Medicine ,Humans ,skin and connective tissue diseases ,Aged ,030203 arthritis & rheumatology ,Hardware_MEMORYSTRUCTURES ,business.industry ,General Medicine ,Middle Aged ,Sexual dysfunction ,Methotrexate ,RL1-803 ,Dermatologic Agents ,medicine.symptom ,business ,medicine.drug - Abstract
is missing (Short communication)
- Published
- 2017
8. The Role of Topical Timolol in the Treatment of Infantile Hemangiomas: A Systematic Review and Meta-analysis
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David Prieto-Merino, Carsten Flohr, A.E. Boyce, Maham Khan, Åke Svensson, and Emma Wedgeworth
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medicine.medical_specialty ,Time Factors ,genetic structures ,medicine.drug_class ,Adrenergic beta-Antagonists ,Timolol ,Antineoplastic Agents ,Dermatology ,Administration, Cutaneous ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Infantile hemangioma ,medicine ,Odds Ratio ,Humans ,030212 general & internal medicine ,Age of Onset ,Adverse effect ,Beta blocker ,Response rate (survey) ,business.industry ,Infant, Newborn ,Infant ,General Medicine ,Odds ratio ,eye diseases ,Surgery ,Tumor Burden ,Treatment Outcome ,Meta-analysis ,sense organs ,Age of onset ,business ,Hemangioma ,medicine.drug - Abstract
To date the efficacy and safety of topical timolol in the treatment of infantile hemangioma has not been reviewed and analysed systematically. We collated all published data on the efficacy and safety of topical timolol in the treatment of infantile hemangioma. A total of 31 studies with 691 patients were included. The fixed effects pooled estimate of the response rate defined as any improvement from baseline of infantile hemangioma after treatment with topical timolol was significant (RR = 8.96; 95% CI 5.07-15.47; heterogeneity test p = 0.99), and the treatment was overall well tolerated. However, the quality of evidence was low to moderate. Topical timolol is an effective treatment for small infantile hemangioma, with no significant adverse effects noted. However, there is still a need for adequately powered randomised controlled trials.
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- 2017
9. Scoring of Hand Eczema: Good Reliability of Hand Eczema Extent Score (HEES)
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Agneta Gånemo, Ingebjörg Holt, Åke Svensson, Monica Hindsén-Stenström, Hans Stenlund, Berndt Stenberg, Birgitta Meding, Irina Baranovskaya, Christopher D. Anderson, and Annica Carlsson
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Adult ,Male ,medicine.medical_specialty ,Eczema ,severity ,Dermatology ,Hand Dermatoses ,Severity of Illness Index ,Inter observer reliability ,030207 dermatology & venereal diseases ,03 medical and health sciences ,Diagnostic Self Evaluation ,0302 clinical medicine ,Severity of illness ,Medicine ,Humans ,Dermatologi och venereologi ,030212 general & internal medicine ,skin and connective tissue diseases ,intra-observer reliability ,Reliability (statistics) ,dermatitis ,Aged ,Observer Variation ,business.industry ,Reproducibility of Results ,General Medicine ,Middle Aged ,self-assessment ,medicine.disease ,Dermatology and Venereal Diseases ,Chronic disease ,Hand eczema ,Chronic Disease ,Physical therapy ,inter-observer reliability ,Female ,business ,Observer variation - Abstract
There is good agreement between dermatological staff and patients using the Hand Eczema Extent Score (HEES). The aim of this study was to assess inter-and intra-observer reliability of the HEES in dermatologists and intra-observer reliability of the HEES in patients with hand eczema. Six dermatologists assessed 18 patients twice. Only the hands of the patients were visible to the assessors. Patients performed a selfassessment twice. Inter-and intra-observer reliability was tested with intraclass correlation coefficient (ICC). The mean HEES score for all dermatologists assessments was 21.0 (range 3.6-46.3). The corresponding mean scores for all patients own assessments were 24.9 (range 4.0-54.0). Inter-observer reliability in the dermatologists observations ICC classification was very good, median value 0.82 (range 0.56-0.92). The overall intra-observer reliability for the 6 dermatologists ICC classification was very good (range 0.88-0.94). Intra-observer reliability in the patients 2 self-assessments ICC classification was very good (ICC 0.95). In conclusion, HEES is a reliable tool for both dermatologists and patients to grade the extent of hand eczema. Funding Agencies|Edward Welander Foundation; Finsen Foundation; Research and Development Fund of Angelholm Hospital
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- 2016
10. What Factors are Important to Patients when Assessing Treatment Response: An International Cross-sectional Survey
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Laura B, von Kobyletzki, Kim S, Thomas, Jochen, Schmitt, Joanne R, Chalmers, Stefanie, Deckert, Valeria, Aoki, Elke, Weisshaar, Jumoke Ahubelem, Ojo, and Åke, Svensson
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Adult ,Male ,Internationality ,Adolescent ,Reproducibility of Results ,Middle Aged ,Severity of Illness Index ,Dermatitis, Atopic ,Cross-Sectional Studies ,Patient Satisfaction ,Child, Preschool ,Surveys and Questionnaires ,Outcome Assessment, Health Care ,Humans ,Female ,Child ,Aged - Abstract
This study investigated the perspective of international patients on individual symptoms of atopic dermatitis (eczema) in determining treatment response. A questionnaire was developed to evaluate the importance of symptoms from the patient's perspective. Patients were asked: "How important are these features in deciding whether or not a treatment is working?", and rated symptoms on a 5-point Likert scale. Patients were approached via Harmonising Outcome Measures for Eczema (HOME) collaborators and self-selected to take part in the on-line survey. Patients from 34 countries (n = 1,111) completed the survey; of these, 423 (38.3%) were parents of children with eczema. Nine items were rated as being "quite important" or "very important" by more than 80% of the respondents: itch, pain/soreness, skin feels hot or inflamed, bleeding, involvement of visible or sensitive body sites, cracks, sleep difficulties, amount of body affected, and weeping/oozing. These results may be of use in determining the face validity of scales from a cross-cultural patients' perspective.
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- 2016
11. Quality of Life in Swedish Children with Eczema
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Magnus Lindberg, Carl-Fredrik Wahlgren, Agneta Gånemo, and Åke Svensson
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Male ,Pediatrics ,medicine.medical_specialty ,Adolescent ,Urticaria ,Eczema ,Dermatology ,Severity of Illness Index ,Atopy ,Quality of life ,immune system diseases ,Surveys and Questionnaires ,Severity of illness ,medicine ,Humans ,SCORAD ,Child ,Conjunctivitis, Allergic ,Asthma ,Sweden ,medicine.diagnostic_test ,business.industry ,Age Factors ,Rhinitis, Allergic, Seasonal ,General Medicine ,Atopic dermatitis ,Dermatology Life Quality Index ,medicine.disease ,Caregivers ,El Niño ,Child, Preschool ,Quality of Life ,Female ,business ,Food Hypersensitivity - Abstract
The burdens of childhood eczema are many and some can be assessed with quality of life (QoL) questionnaires. Seventy-eight Swedish children with mild-to-severe eczema ("atopic dermatitis", prurigo Besnier), fulfilling established diagnostic criteria, were investigated for the effect of eczema on QoL. This was measured with validated questionnaires: the Infants' Dermatitis Quality of Life Index (IDQOL), the Children's Dermatology Life Quality Index (CDLQI), and the Dermatitis Family Impact Questionnaire (DFI). The study also included scoring of eczema severity. The median score was 7.0 (range 1-18) for IDQOL, 6.0 (range 2-18) for the CDLQI, and 8.0 (range 0-27) for DFI. There was no significant difference in scores between boys and girls. The DFI scores were higher for younger than for older children, and also higher for those with both eczema and asthma, food allergy/intolerance, allergic rhinoconjunctivitis or urticaria. The QoL scores correlated significantly with the Rajka & Langeland score, but not with objective SCORAD. The outcome of the QoL instruments in this study clearly demonstrates that childhood eczema affects the children's and their families' QoL. QoL data offers a patient-oriented outcome measure of importance for understanding the patients' and their families' situation. Such information can also be used in intervention studies and in the allocation of healthcare resources to eczema care.
- Published
- 2007
12. The Occurrence of Atopic Dermatitis in Greenland
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Åke Svensson, Finn Schultz Larsen, Ellis From, and Thomas L. Diepgen
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Male ,medicine.medical_specialty ,Pediatrics ,Allergy ,Cross-sectional study ,Greenland ,Dermatology ,Standard score ,Dermatitis, Atopic ,Atopy ,Surveys and Questionnaires ,Epidemiology ,Prevalence ,medicine ,Humans ,Child ,business.industry ,General Medicine ,Atopic dermatitis ,medicine.disease ,Confidence interval ,body regions ,Cross-Sectional Studies ,El Niño ,Female ,business ,Demography - Abstract
Until recently there was no information available on the prevalence of atopic dermatitis in Greenland. Our objective was to determine the prevalence of atopic dermatitis in younger schoolchildren in Greenland. In the autumn of 2000 we used our previously elaborated questionnaire in a cross-sectional study of 954 schoolchildren aged 7-8 years, who lived in five Greenlandic towns. The findings were compared to data on atopic dermatitis from Denmark. The response rate was 65% (622). The lifetime prevalence of atopic dermatitis was calculated to be 14.0% (95% confidence interval 11.3-16.7) using our standard score criteria with an absolute lower limit estimate of 4.5%. Taking the response rate of 65% into consideration this study indicates that in 2000 the lifetime prevalence of atopic dermatitis among younger schoolchildren in Greenland was in the range of 10-15%.
- Published
- 2005
13. Prevalence of Self-reported Hand Dermatosis in Upper Secondary School Pupils
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Åke Svensson, Å. Isacsson, and M Yngveson
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Male ,medicine.medical_specialty ,Population ,Prevalence ,Hand Dermatoses ,Dermatology ,Hand Dermatosis ,Surveys and Questionnaires ,medicine ,Humans ,Child ,Prospective cohort study ,education ,Sweden ,Secondary level ,education.field_of_study ,business.industry ,Validated questionnaire ,General Medicine ,Surgery ,Data Interpretation, Statistical ,Etiology ,Female ,business ,Demography - Abstract
The purpose of the present study was to estimate the prevalence of self-reported hand dermatosis among upper secondary school pupils. All pupils in grades 1 and 3 from the four upper secondary schools in Vaxjo, southern Sweden, were invited to participate in the study. A previously validated questionnaire was used. Of the 2609 invited pupils, 2572 (98.6%) responded to the questionnaire. The point prevalence of self-reported hand dermatosis was 4.2% (95% CI, 3.4-4.9%) with no significant differences between gender and grades. The overall one-year prevalence of self-reported hand dermatosis was 10.0% (95% CI, 8.8-11.1%), i.e. the corresponding figures for males were 7.3% (95% CI, 5.9-8.8%) and for females 12.5% (95% CI, 10.6-14.6%). There were significant gender differences in grade 1 (p < 0.001) and in grade 3 (p < 0.05). Males and females from the hotel and restaurant course had the highest one-year prevalence in grade 3. It is concluded that the high point and one-year prevalence of hand dermatosis among upper secondary school pupils merits long-term prospective study in order to address the question of which aetiological or trigger factors are most important in the development of hand dermatosis in a population.
- Published
- 1998
14. Factors associated with remission of eczema in children: a population-based follow-up study
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Malin Larsson, Åke Svensson, Carl-Gustaf Bornehag, Cecilia Boman Lindström, Elizabeth Breeze, and Laura B von Kobyletzki
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Male ,Rural Population ,Pediatrics ,medicine.medical_specialty ,Population ,Dermatology ,Logistic regression ,Severity of Illness Index ,Dermatitis, Atopic ,Cohort Studies ,Recurrence ,Surveys and Questionnaires ,Severity of illness ,medicine ,Humans ,Age of Onset ,education ,Sweden ,education.field_of_study ,business.industry ,Infant ,General Medicine ,Odds ratio ,Atopic dermatitis ,medicine.disease ,Confidence interval ,Dermatology and Venereal Diseases ,Child, Preschool ,Cohort ,Female ,business ,Cohort study ,Follow-Up Studies - Abstract
The aim of this study was to analyse factors associated with remission of atopic dermatitis (AD) in childhood. A population-based AD cohort of 894 children aged 1-3 years from a cross-sectional baseline study in 2000 was followed up in 2005. The association between remission, background, health, lifestyle, and environmental variables was estimated with crude and multivariable logistic regression. At follow-up, 52% of the children had remission. Independent factors at baseline predicting remission were: milder eczema (adjusted odds ratio (aOR), 1.43; 95% confidence interval (95% CI) 1.16-1.77); later onset of eczema (aOR 1.40; 95% CI 1.08-1.80); non-flexural eczema (aOR 2.57; 95% CI 1.62-4.09); no food allergy (aOR 1.51; 95% CI 1.11-2.04), and rural living (aOR 1.48; 95% CI 1.07-2.05). Certain aspects of AD and rural living were important for remission, but despite the initial hypotheses to the contrary, the environmental factors examined in this paper were not substantial predictors of remission.
- Published
- 2013
15. Self-reported lifetime prevalence of atopic dermatitis and co-morbidity with asthma and eczema in adulthood: a population-based cross-sectional survey
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Kristina Bingefors, Dag Isacson, Magnus Lindberg, and Åke Svensson
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Male ,Medicin och hälsovetenskap ,Allergy ,Time Factors ,Urticaria ,Cross-sectional study ,Eczema ,Comorbidity ,Medical and Health Sciences ,immune system diseases ,Risk Factors ,Odds Ratio ,Prevalence ,Young adult ,Age of Onset ,skin and connective tissue diseases ,Aged, 80 and over ,education.field_of_study ,atopic dermatitis ,General Medicine ,Atopic dermatitis ,Middle Aged ,epidemiology ,Female ,Adult ,medicine.medical_specialty ,Adolescent ,Population ,Dermatology ,Risk Assessment ,Dermatitis, Atopic ,Young Adult ,otorhinolaryngologic diseases ,medicine ,Humans ,co-morbidity ,education ,Asthma ,Aged ,Sweden ,business.industry ,Odds ratio ,asthma ,medicine.disease ,Health Surveys ,body regions ,Cross-Sectional Studies ,Logistic Models ,Self Report ,Age of onset ,business - Abstract
Atopic dermatitis and its co-morbidity with asthma and allergy is well described in younger age groups. However, population-based studies on adults with atopic dermatitis in childhood are sparse. The aims of this study were to determine: (i) the prevalence of self-reported childhood atopic dermatitis in the population; and (ii) its association with present self-reported hand eczema, eczema, allergy, urticaria and asthma. A questionnaire was sent to a cross-sectional random sample of the Swedish population (n = 7,985), age range 18-84 years (response rate 61.1%). The questionnaire included the question "Have you had childhood eczema?" and questions on 5 other medical problems (hand eczema, other eczema, asthma, urticaria and allergy). Persons reporting eczema in childhood reported increased odds ratios (OR) for hand eczema (4.01), other eczema (3.88), urticaria (2.50), allergy (2.98), and asthma (2.06) as adults. The combination of eczema, allergy and asthma had an OR of 14.10 (95% confidence interval 8.44-23.54). Adults in the age range 18-84 years reporting childhood atopic dermatitis still have high co-morbidity with eczema, asthma, urticaria and allergy.
- Published
- 2013
16. A Double-Blind Study Comparing the Effect of Glycerin and Urea on Dry, Eczematous Skin in Atopic Patients
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Åke Svensson, Thomas Frödin, Tore Särnhult, Eva Pawlik, Hans Ohman, M Lodén, Mari-Helen Sandström, Magnus Lindberg, Christopher D. Anderson, Anna Preisler-Häggqvist, Ing-Marie Bergbrant, Berndt Stenberg, Anna-Carin Andersson, and Ewa Voog
- Subjects
Adult ,Glycerol ,Male ,Allergy ,medicine.medical_specialty ,Administration, Topical ,Skin Absorption ,medicine.medical_treatment ,Eczema ,Dermatology ,Sodium Chloride ,Placebo ,medicine.disease_cause ,Severity of Illness Index ,Drug Administration Schedule ,Statistics, Nonparametric ,Dermatitis, Atopic ,Ointments ,Double-Blind Method ,Reference Values ,Dry skin ,medicine ,Humans ,Urea ,skin and connective tissue diseases ,Aged ,Probability ,Dose-Response Relationship, Drug ,integumentary system ,business.industry ,digestive, oral, and skin physiology ,food and beverages ,General Medicine ,Atopic dermatitis ,Middle Aged ,medicine.disease ,Water Loss, Insensible ,Drug Combinations ,Treatment Outcome ,Itching ,Dryness ,Female ,Dermatologic Agents ,Moisturizer ,medicine.symptom ,Irritation ,business ,Follow-Up Studies - Abstract
Moisturizing creams have beneficial effects in the treatment of dry, scaly skin, but they may induce adverse skin reactions. In a randomized double-blind study, 197 patients with atopic dermatitis were treated with one of the following: a new moisturizing cream with 20% glycerin, its cream base without glycerin as placebo, or a cream with 4% urea and 4% sodium chloride. The patients were asked to apply the cream at least once daily for 30 days. Adverse skin reactions and changes in skin dryness were assessed by the patient and a dermatologist. Adverse skin reactions such as smarting (a sharp local superficial sensation) were felt significantly less among patients using the 20% glycerin cream compared with the urea-saline cream, because 10% of the patients judged the smarting as severe or moderate when using glycerin cream, whereas 24% did so using urea-saline cream (p < 0.0006). No differences were found regarding skin reactions such as stinging, itching and dryness/irritation. The study showed equal effects on skin dryness as judged by the patients and the dermatologist. In conclusion, a glycerin containing cream appears to be a suitable alternative to urea/sodium chloride in the treatment of atopic dry skin.
- Published
- 2002
17. Are treatment satisfaction, quality of life, and self-assessed disease severity relevant parameters for patient registries? Experiences from Finnish and Swedish patients with psoriasis
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Jonas Hjelmgren, Annika Bergman, H. Heikkilä, Catharina Hjortsberg, Åke Svensson, Anton Bjarnason, Gunnel Ragnarson Tennvall, and Department of Dermatology, Allergology and Venereology
- Subjects
Male ,Time Factors ,IMPACT ,Disease ,Severity of Illness Index ,030207 dermatology & venereal diseases ,0302 clinical medicine ,Cost of Illness ,Surveys and Questionnaires ,Registries ,Finland ,GENERAL-POPULATION ,PLACEBO ,General Medicine ,patient registries ,Middle Aged ,3. Good health ,Treatment Outcome ,Patient Satisfaction ,030220 oncology & carcinogenesis ,SAFETY ,disease severity ,Female ,BURDEN ,Adult ,medicine.medical_specialty ,education ,Dermatology ,Placebo ,Treatment satisfaction ,HRQoL ,03 medical and health sciences ,MEMBERSHIP SURVEY ,Diagnostic Self Evaluation ,Young Adult ,Patient satisfaction ,Quality of life (healthcare) ,Disease severity ,Psoriasis ,medicine ,Humans ,Intensive care medicine ,Disease burden ,Aged ,Retrospective Studies ,Sweden ,business.industry ,medicine.disease ,EFFICACY ,3141 Health care science ,Physical therapy ,Quality of Life ,business - Abstract
Patient registries often lack indicators of the disease as experienced by patients, e.g. treatment satisfaction and self-assessed disease severity. There is scarce information about the relationship between these assessments and currently existing instruments used in treatment evaluation. Our objective was to explore the importance of these indicators among patients with psoriasis in Finland and Sweden, in relation to treatment patterns and current measures of health-related quality of life. Data were collected from a patient survey and a retrospective chart review for 273 patients over 12 months. To assess psoriasis treatment completely, it is necessary to consider the impact of the disease on the patient in terms of treatment satisfaction, disease severity and health-related quality of life. The individual disease burden on patients should play a central role in formulating treatment goals. Clinician- and patient-based perspectives of the overall impact of psoriasis can assist clinical decision-making and evaluations of treatments.
- Published
- 2011
18. Prevalence of hand eczema in an adult Swedish population and the relationship to risk occupation and smoking
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Claes-Göran Löfdahl, Åke Svensson, Peter Montnemery, Per Nyberg, and Ulf Nihlén
- Subjects
Adult ,Male ,Pediatrics ,medicine.medical_specialty ,Adolescent ,Population ,Eczema ,Dermatology ,Hand Dermatoses ,Postal questionnaire ,Swedish population ,Epidemiology ,medicine ,Prevalence ,Humans ,Multiple logistic regression analysis ,Risk factor ,Occupations ,education ,Aged ,Response rate (survey) ,Sweden ,education.field_of_study ,business.industry ,Smoking ,General Medicine ,Middle Aged ,medicine.disease ,Dermatitis, Occupational ,Hand eczema ,Female ,business ,Demography - Abstract
Using a postal questionnaire the prevalence of hand eczema was determined in a general population of 11 798 individuals aged 20 - 77 years who were randomly drawn from the population records. The response rate was 78.1%. One-year prevalence of hand eczema among women varied between 1.9% and 10.8%, with the highest figure among those aged 30 - 39 years. The corresponding figures for men were 2.3% and 5.6%, with the highest figure among those aged 20 - 29 years. Lifetime prevalence varied between 5.7% and 16.7% among women and between 5.2% and 9.5% among men. Using multiple logistic regression analysis female sex (OR = 1.91, 95% CI 1.47 - 2.47) and smoking (OR = 1.35, 95% CI 1.04 - 1.75) were independent risk factors for reporting 1-year prevalence of hand eczema, whereas age (OR = 0.99, 95% CI 0.97 - 0.99) was inversely related to the 1-year prevalence of hand eczema. Aggregated risk occupation or categorized occupation such as medical and nursing work, production or service were not significantly associated with 1- year prevalence of hand eczema.
- Published
- 2005
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