1. Multidisciplinary Management of Mastocytosis: Nordic Expert Group Consensus
- Author
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Lene H. Garvey, Charlotte G. Mortz, Gunnar Nilsson, Peter Valent, Thomas Kielsgaard Kristensen, Ole Weis Bjerrum, Leena Ackermann, Trine Torfing, Theo Gülen, Maria Sääf, Eva Stylianou, Carsten Bindslev-Jensen, Ingunn Dybedal, Hanne Vestergaard, Birgitta Sander, Michael Boe Møller, Troels Havelund, Marie Bendix, Sigurd Broesby-Olsen, Anna Bergström, Maria A Karlsson, Lone Agertoft, Kim Brixen, Hans Hägglund, Pernille Hermann, Department of Dermatology, Allergology and Venereology, and Clinicum
- Subjects
Diagnostic criteria ,Disease ,BONE-MARROW HISTOPATHOLOGY ,030207 dermatology & venereal diseases ,0302 clinical medicine ,Multidisciplinary approach ,multidisciplinary management ,Prevalence ,TRYPTASE LEVELS ,Systemic mastocytosis ,CUTANEOUS-MASTOCYTOSIS ,Mast cell activation ,General Medicine ,Classification ,Expert group ,3. Good health ,classification ,030220 oncology & carcinogenesis ,Practice Guidelines as Topic ,GASTROINTESTINAL-TRACT ,MAST-CELL ACTIVATION ,Mastocytosis ,medicine.medical_specialty ,Consensus ,KIT D816V MUTATION ,INDOLENT SYSTEMIC MASTOCYTOSIS ,Dermatology ,systemic mastocytosis ,Scandinavian and Nordic Countries ,World Health Organization ,PEDIATRIC MASTOCYTOSIS ,Mast cell ,EUROPEAN COMPETENCE NETWORK ,Diagnosis, Differential ,03 medical and health sciences ,Multidisciplinary management ,medicine ,Humans ,Intensive care medicine ,RESPONSE CRITERIA ,Urticaria pigmentosa ,business.industry ,Cutaneous Mastocytosis ,Congresses as Topic ,medicine.disease ,3121 General medicine, internal medicine and other clinical medicine ,diagnostic criteria ,Immunology ,Differential diagnosis ,mast cell ,business ,urticaria pigmentosa - Abstract
Mastocytosis is a heterogeneous group of diseases defined by an increased number and accumulation of mast cells, and often also by signs and symptoms of mast cell activation. Disease subtypes range from indolent to rare aggressive forms. Mastocytosis affects people of all ages and has been considered rare; however, it is probably underdiagnosed with potential severe implications. Diagnosis can be challenging and symptoms may be complex and involve multiple organ-systems. In general it is advised that patients should be referred to centres with experience in the disease offering an individualized, multidisciplinary approach. We present here consensus recommendations from a Nordic expert group for the diagnosis and general management of patients with mastocytosis.
- Published
- 2015
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