The Spanish flu pandemic is considered the largest and most dangerous epidemic at the beginning of the 20th century affecting most of the world today. The Spanish flu pandemic did not bypass the territory of Croatia (at the time, Croatia was part of the Austro-Hungarian Monarchy), nor its southern coastal region of Dalmatia and the city of Split. Using the example of the city Split, the paper analyses the spatial and demographic determinants of population mortality from the Spanish flu between 1918 and 1919, i.e., from March 1918 to April 1919. The paper is based on the data of the Church Death registers kept in the Archbishop’s Archives in Split and newspaper articles. The analysis of the spatial distribution of mortality within urban settlements showed that the number of deaths per urban settlement was significantly influenced by population density but also by the socio-economic conditions of the war and post-war period. The paper analyses the articles of the New Age that refer to the Spanish flu for monitoring the course and spread of the disease, as well as the reading of information but also shaping of public opinion. Analysis of social and demographic aspects of mortality caused by the pandemic in 1918 and 1919 in Split did not indicate any deviations from other areas of Croatia and the rest of the world. In this way, the age-sex, spatial and social framework of mortality and the media framework are analogues to other national and foreign researched areas. [ABSTRACT FROM AUTHOR]